Comparison of the Long-term Clinical Results of Hydrophilic and Hydrophobic Acrylic Intraocular Lenses

Suh, Yoon Seok; Oh, Chung-Hoon; Kim, Hyo Myung

doi:10.3341/kjo.2005.19.1.29

Cited by 11 publications

(12 citation statements)

References 24 publications

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“…However, a recent study showed that post-operative refractive values are no different between hydrophobic and hydrophilic acrylic IOLs 3 months post-operatively. 20 In addition, the optic diameters of both types of IOLs used in this study were the same. Long-acting gas may also influence myopic shifts of the IOL.…”

Section: Discussionmentioning

confidence: 99%

Effects of the Intraocular Lens Type on Refractive Error Following Phacovitrectomy with Gas Tamponade

Hwang

Jee

2011

Current Eye Research

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Section: Discussionmentioning

confidence: 99%

Effects of the Intraocular Lens Type on Refractive Error Following Phacovitrectomy with Gas Tamponade

Hwang

Jee

2011

Current Eye Research

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“…Suh et al [32] evaluated the effect of hydrophilic and hydrophobic acrylic IOLs on PCO. Over the 3-year follow-up of cases, the authors reported that PCO developed in 20.3% of those who had undergone hydrophilic acrylic IOL implantation and 6.8% of those who had undergone hydrophobic acrylic IOL implantation, and they performed Nd:YAG laser capsulotomy in all of the cases that developed PCO.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Nd:YAG laser capsulotomy results in patients who underwent cataract extraction and intraocular lens implantation with the endocapsular phacoemulsification method

Yetkin

2023

J Surg Med

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Background/Aim: Posterior capsular opacification (PCO) is a common complication that develops after cataract surgery, and it can be treated neodymium-doped yttrium aluminum garnet (Nd:YAG) laser capsulotomy. In this study, we aimed to investigate the effects of different intraocular lenses (IOLs) on the development of posterior capsule opacification (PCO), to determine the time between surgery and Nd:YAG laser capsulotomy, and to evaluate the efficacy, effectiveness, and complications of capsulotomy in patients who underwent cataract surgery with the phacoemulsification method and subsequently developed PCO. Methods: The cohort study included one eye of each of 153 cases (63 males, 90 females) who underwent cataract surgery with the phacoemulsification method in our clinic from August 1, 2006, through August 1, 2008, and subsequently developed PCO. According to the type of IOL implanted, the cases were divided into three groups: polymethylmethacrylate IOL (Group 1), hydrophilic acrylic IOL (Group 2), and hydrophobic acrylic IOL (Group 3). The control examinations of the patients who underwent Nd:YAG laser capsulotomy were undertaken before capsulotomy and at the first week, first month, and third month after capsulotomy. Results: Visual acuity improvement was detected in 96.7% of the 153 cases. It was determined that 9.1% of the cases had an intraocular pressure (IOP) increase of more than 5 mmHg at the third hour after capsulotomy and approached baseline values at the end of 1 week. The mean total energy used in all the cases was 37.20 (14.70) mjl. The mean total energy used in 14 patients with an IOP elevation of above 5 mmHg was 71.07 (10.59) mjl. Nd:YAG laser capsulotomy was performed at an average of 6.29 (4.91) months in Group 1, 7.81 (4.35) months in Group 2, and 17.7 (12.35) months in Group 3. After capsulotomy, clinically significant cystoid macular edema was observed in 1.9% of the cases, IOL damage in 3.9%, and vitreous hemorrhage in 0.6%. Conclusion: In this study, the incidence of PCO development was found to be lower in the patients who underwent hydrophobic acrylic IOL implantation; therefore, this type of lens should be preferred for implantation. Although Nd:YAG laser capsulotomy is an outpatient treatment method that can be applied quickly and can increase visual acuity, it can also lead to complications. To eliminate most of these complications, it would be beneficial to minimize the energy used during the laser procedure.

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“…Before, during and after pH adjustment of the supersaturated solutions, inert atmosphere over the solution was ensured by pumping through the solutions, pure nitrogen (99.99%, Linde Hellas, Ltd., Schematari, Greece) saturated with water vapor. Following the verification of the stability of the supersaturated solutions, as shown by the stability of the adjusted pH value for at least two hours, a set of hydrophilic IOL lenses (3)(4)(5), mounted firmly on a special holder which allowed exposure of both the anterior and the posterior sides, were immersed in the supersaturated solution. The pH of the solutions was monitored.…”

Section: Constant Composition Reactor (Ccr)mentioning

confidence: 99%

“…Various biomaterials have been used since 1949, for the fabrication of IOL and since then research is intense concerning materials development and biocompatibility. Over the past two decades, calcification has been reported with a few hydrophilic IOLs, and subsequently, a number of these IOLs were explanted [3][4][5][6]. Calcification response after IOL implantation depends on both the composition of the aqueous humor (AH) and on the material of construction of the IOLs.…”

Section: Introductionmentioning

confidence: 99%

Biological Mineralization of Hydrophilic Intraocular Lenses

et al. 2022

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Biomaterials calcify upon implantation in contact with biological fluids, which are supersaturated with respect to more than one crystalline phase of calcium phosphate. The implantation of intraocular lenses (IOLs) for cataract treatment has been hailed as a major advance. Hydrophilic acrylic IOLs, made of Poly(2-hydroxyethyl methacrylate) (PHEMA), upon contact with aqueous humor, exhibit significant incidence of opacification, due to the formation of calcium phosphate crystals, mainly hydroxyapatite (Ca5(PO4)3OH, HAP) on the surface or in their interior. The aqueous humor is supersaturated with respect to HAP. Clinical findings were duplicated by laboratory experiments through the development of appropriate experimental models which included batch reactors, well stirred operating at constant supersaturation (CCR) and reactors simulating anterior eye chamber (ECSR). In both CCR and ECSR, simulated aqueous humor was used. In ECSR the flow rate was the same as in the eye chamber (2.5 mL per 24 h). HAP formed both on the surface and inside the IOLs tested. Induction times preceding the crystallization of HAP on the surface of the IOLs and crystal growth rates were measured. Surface hydroxyl ionized groups favored the development of locally high supersaturation by surface complexation. In the interior of the IOLs, HAP formed by the diffusion of the calcium and phosphate ions inside the polymeric matrix.

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Comparison of the Long-term Clinical Results of Hydrophilic and Hydrophobic Acrylic Intraocular Lenses

Cited by 11 publications

References 24 publications

Effects of the Intraocular Lens Type on Refractive Error Following Phacovitrectomy with Gas Tamponade

Effects of the Intraocular Lens Type on Refractive Error Following Phacovitrectomy with Gas Tamponade

Evaluation of Nd:YAG laser capsulotomy results in patients who underwent cataract extraction and intraocular lens implantation with the endocapsular phacoemulsification method

Biological Mineralization of Hydrophilic Intraocular Lenses

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