Clinical outcomes of extended esophagectomy with three-field lymph node dissection for esophageal squamous cell carcinoma

Tachibana, Mitsuo; Kinugasa, Shoichi; Yoshimura, Hiroshi; Shibakita, Muneaki; Tonomoto, Yasuhito; Dhar, Dipok Kumar; Nagasue, Naofumi

doi:10.1016/j.amjsurg.2004.10.001

Cited by 160 publications

(123 citation statements)

References 47 publications

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“…Several clinical investigations show that depth of infiltration and lymph-node metastasis are independent risk factors of poor prognosis (Rice et al, 1998;Kunisaki et al, 2005;Tachibana et al, 2005). Hu et al (2010) used the number of lymph node metastasis, the degree of metastasis, and the number of involved lymphatic regions to stratify the patients.…”

Section: Discussionmentioning

confidence: 99%

Prognostic Significance of CYFRA21-1, CEA and Hemoglobin in Patients with Esophageal Squamous Cancer Undergoing Concurrent Chemoradiotherapy

Zhang

Wang²,

Huang³

et al. 2012

Asian Pacific Journal of Cancer Prevention

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Section: Discussionmentioning

confidence: 99%

Prognostic Significance of CYFRA21-1, CEA and Hemoglobin in Patients with Esophageal Squamous Cancer Undergoing Concurrent Chemoradiotherapy

Zhang

Wang²,

Huang³

et al. 2012

Asian Pacific Journal of Cancer Prevention

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“…Radical esophagectomy is the primary curative therapy for patients with esophageal cancer, and recent progress in surgical and postoperative management techniques has improved treatment outcomes (1). However, esophageal resection is associated with considerable morbidity and mortality.…”

Section: Introductionmentioning

confidence: 99%

Risk factors for postoperative respiratory complications following esophageal cancer resection

et al. 2012

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Abstract. The development of surgical and postoperative management techniques has improved the treatment outcomes of esophageal cancer resection. However, respiratory morbidity is still the most frequent complication after esophagectomy. The objective of the present study was to identify risk factors for respiratory complications following resection for esophageal cancer. This study included 96 patients with esophageal cancer who had undergone esophagectomy with lymph node dissection. The patients were divided into 2 groups according to the presence (20 patients, 17 had pneumonia and 3 had acute respiratory distress syndrome) or absence (76 patients) of postoperative respiratory complications (PRC). The two groups were compared with respect to their preoperative clinical variables, such as age, body mass index, smoking history, serum albumin, serum C-reactive protein (CRP), number of lymphocytes, %VC, FEV1.0% and FEV1.0. Furthermore, multiple logistic regression analyses were used to estimate relative risk factors for respiratory complications. Results of the univariate analysis showed that smoking history (+/-, patients with PRC, 19/1 and without PRC, 53/23), serum CRP (≥1.0 mg/ dl/<1.0 mg/dl, patients with PRC, 6/14 and without PRC, 6/70) and FEV1.0% (≥60%/<60%, patients with PRC, 16/4 and without PRC, 73/3) were significantly different between the two groups. Multiple logistic regression analysis showed that FEV1.0% was the strongest predictor of PRC. FEV1.0%, serum CRP and smoking history are reliable predictors of the risk of respiratory complications following esophageal cancer resection. For patients with these factors, perioperative management for the prevention of postoperative respiratory complications should be considered.

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“…Many previous reports have shown the superiority of 3FLD as compared with twofield LN dissection (2FLD). [20][21][22][23][24][25][26][27] The discussion regarding the extent of LN dissection has mainly centered on thoracic esophageal SCC in Japan.…”

Section: Surgical Treatmentmentioning

confidence: 99%

Current Status and Future Prospects for Esophageal Cancer Treatment

Sohda

Kuwano

2017

ATCS

158

126

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Clinical outcomes of extended esophagectomy with three-field lymph node dissection for esophageal squamous cell carcinoma

Cited by 160 publications

References 47 publications

Prognostic Significance of CYFRA21-1, CEA and Hemoglobin in Patients with Esophageal Squamous Cancer Undergoing Concurrent Chemoradiotherapy

Prognostic Significance of CYFRA21-1, CEA and Hemoglobin in Patients with Esophageal Squamous Cancer Undergoing Concurrent Chemoradiotherapy

Risk factors for postoperative respiratory complications following esophageal cancer resection

Current Status and Future Prospects for Esophageal Cancer Treatment

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