Clinacanthus nutans : A review of the medicinal uses, pharmacology and phytochemistry

Abstract

Clinacanthus nutans Lindau is known as snake grass belonging to the Acanthaceae family. This plant has diverse and potential medicinal uses in traditional herbal medicine for treating skin rashes, insects and snake bites, lesions caused by herpes simplex virus, diabetes, and gout in Malaysia, Indonesia, Thailand and China. Phytochemical investigations documented the varied contents of bioactive compounds from this plant namely flavonoids, glycosides, glycoglycerolipids, cerebrosides and monoacylmonogalatosylglycerol. The pharmacological experiment proved that various types of extracts and pure compounds from this species exhibited a broad range of biological properties such as anti-inflammatory, antiviral, antioxidant, and anti-diabetic activities. The findings of toxicity study showed that extracts from this plant did not show any toxicity thus it can be used as strong therapeutic agents for specific diseased conditions. However, further experiments on chemical components and their mode of action showing biological activities are required to elucidate the complete phytochemical profile and assess to confirm their suitability for future drugs. This review summarizes the medicinal uses, phytochemistry and pharmacology of this plant in order to explore its therapeutic potential and gaps necessitating for prospected research work.

Evaluation on the effects of P. ostreatus spent mushroom compost and BAP hormone towards C. nutans in vitro culture

“…The commercial benefits of the C. nutans leaves in pharmaceutical and health products [23] had led to numerous study focuses on high production of leaves via in vitro culture. Thus, the number of leaves in each successfully regenerated explant is also one of the parameter that is…”

“…It was found that by ion of BAP together with SMC percentage had generated longer 8, the most optimum media for shoots growth is media treated with 1 mg/L BAP and 2% SMC as it increase the shoot length up to 1.6 ±0.36 cm. The 22] in their studies that propose SMC is a this further explained on the result nutans leaves in pharmaceutical and health products [23] had led to numerous study focuses on high production of leaves via in vitro culture. Thus, the number of leaves in each successfully regenerated explant is also one of the parameter that is recorded having similarity with study done by [24].…”

Phytochemical Evaluation of Polyherbal Formulation of Clinacanthus nutans and Elephantopus scaber to Identify Flavonoids

“…This plant has diverse and potential medicinal uses in traditional herbal medicine for treating skin rashes, insects and snake bites, lesions caused by herpes simplex virus, diabetes, and gout in Malaysia, Indonesia, Thailand, and China. 4 Elephantopus scaber Linn. is known as Prickly-leaves elephant's foot, tutup bumi in Malay or di dan tou in Chinese.…”

Clinacanthus nutans Aqueous Extract But Not Ethanolic Extract Inhibits the Release of Preformed Mediators in In Vitro Model of IgE-Mediated Mast Cell Degranulation

“…f.) Lindau (C. nutans) is a perennial shrub that can be found in Malaysia, Indonesia, Thailand and has been used traditionally by the locals to cure a variety of illnesses [1] . Traditionally consumed as an…”

“…Original Research Article herbal tea in Malaysia or as blended raw material in juice or used as an external treatment [1] , this plant has gained much popularity as an anti-cancer treatment option among Malaysians [2,3] . The fresh leaves of C. nutans have also been used traditionally to relieve insect bites and skin rashes [2,[4][5][6] .…”