Chemical Constituents of Snake Fruit (Salacca zalacca (Gaert.) Voss) Peel and in silico Anti-aging Analysis

Abstract

Background: Skin aging is a condition where skin is unable to retain both its physiological and structural integrity. Plants is the main source of phtytochemicals compound with wide range of biological activities. Through the efforts of ongoing scientific researches, an increasing number of plant extracts and phytochemicals have been showed promising result as anti-aging agent. Snake fruit (Salacca zalacca (Gaert.) Voss) is tropical plant belongs to the palm tree family (Arecaceae) that served as important crop in Indonesia. Despite its utilization, the phytochemical compound available in snake fruit, especially its peel have not been well documented. Present study aimed to elucidate the phytochemical constituent of snake fruit peel and its anti-aging potency.Materials and Methods: Snake fruit peel extract (SPE) was subjected to qualitative phytochemical assay, high performance liquid chromatography, and molecular docking towards protein related in skin aging.Results: The screening showed SPE contained phytochemical compound belong to flavonoid, tannin, phenol, triterpenoid, saponin and alkaloid. Thus, based on the analysis only chlorogenic acid was present in SPE whilst rutin and caffeic acid were not detected. The SPE was contained chlorogenic acid around 1.074 mg/g dry weight. Chlorogenic acid had the high binding affinity towards matrix metalloproteinase (MMP)-1 (-9.4 kcal/mol).Conclusion: Current findings may provide scientific evidence for possible usage of SPE and its compounds as antioxidant and anti-aging agent.Keywords: Salacca zalacca, phytochemical compound, high performance liquid chromatography, anti-aging

Potentials of rose (Rosa damascena) petals and receptacles extract as antioxidant and antihyaluronidase

“…RPE and RRE yields were 88.56 g and 2.72 g, respectively. The extracts were stored at -20°C (Asan et al, 2019;Girsang et al, 2019;Liana et al, 2019;Vrianty et al, 2019;Widowati et al, 2018b).…”

Antioxidant and Elastase Inhibitor Potential of Petals and Receptacle of Rose Flower (Rosa damascena)

“…The both extract RPE and RRE were later diluted in dimethyl sulfoxide (DMSO) with following concentrations: 5000, 2500, 1250, 625, 312.50, 156.25, 1000, 500, 250, 125, 62.50, and 31.25 µg/mL. This dilution are later called working concentrations (Mahadi et al, 2019;Vrianty et al, 2019;Siregar et al, 2019;Girsang et al, 2019;Liana et al, 2019;Asan et al, 2019;Prahastuti et al, 2020).…”

“…(Utami et al, 2018), black soybeans (Glycine max [L.] Merr) (Asan et al, 2019), dragon fruit peel (Hylocereus polyrhizus) (Liana et al, 2019), pineapple (Vrianty et al, 2019), and zalacca skin (Salacca zalacca (Gaert.) Voss) (Girsang et al, 2019). Sources of antioxidants are mangosteen peel (Garcinia mangostana L.) (Widowati et al, 2014), black tea, green tea, oolong tea (Camelia sinensis L.) (Widowati et al, 2015), green meniran (Phyllanthus niruri) (Rusmana et al, 2017), black soybean (Glycine max L. Merr) (Asan et al, 2019), dragon fruit peel (Hylocereus polyrhizus) (Liana et al, 2019), pineapple (Vrianty et al, 2019), and zalacca bark (Salacca zalacca (Gaert.)…”

“…Sources of antioxidants are mangosteen peel (Garcinia mangostana L.) (Widowati et al, 2014), black tea, green tea, oolong tea (Camelia sinensis L.) (Widowati et al, 2015), green meniran (Phyllanthus niruri) (Rusmana et al, 2017), black soybean (Glycine max L. Merr) (Asan et al, 2019), dragon fruit peel (Hylocereus polyrhizus) (Liana et al, 2019), pineapple (Vrianty et al, 2019), and zalacca bark (Salacca zalacca (Gaert.) Voss) (Girsang et al, 2019). In addition, plants that are beneficial for health and skin are Aloe vera plants (Surjushe et al, 2008).…”

Struktur Morfoanatomi Bunga, Daun dan Akar Salak Pondoh (Salacca edulis Reinw.) pada Beberapa Daerah di Kabupaten Magelang

“…Salak juga memiliki kandungan antioksidan yang tinggi (Saleh et al, 2018). Tanaman salak merupakan tanaman asli Indonesia (Girsang et al, 2019). Salah satu jenis salak adalah salak pondoh Salak pondoh mulai dikembangkan tahun 1980an, salak yang manis dan garing ini menjadi buah primadona yang penting di wilayah DIY (Hastuti, 2013) dan sekitarnya.…”