Chemical constituents, in vitro anti-inflammatory, antioxidant and hemostatic activities of the n-butanol extract of Hyacinthoides lingulata (Poir.) Rothm

Hanfer, Mourad; Benramdane, Zeyneb; Cheriet, Thamere; Sarri, Djamel; Mustafa, Ahmed M.; Mancini, Ines; Seghiri, Ramdane; Ameddah, Souad

doi:10.1080/14786419.2021.1937153

Cited by 5 publications

(2 citation statements)

References 14 publications

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“…It is well known that phenolics-rich plant extracts are good scavengers of free-radicals in this assay, and the extracts containing luteolin derivatives are no exception. The examples include the extracts of Thymus serpyllum [ 49 ] and Hyacinthoides lingulata [ 50 ].…”

Section: Resultsmentioning

confidence: 99%

Glycerol and Natural Deep Eutectic Solvents Extraction for Preparation of Luteolin-Rich Jasione montana Extracts with Cosmeceutical Activity

et al. 2022

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Jasione montana is a plant from the family Campanulaceae rich in phenols with health-beneficial properties such as luteolin (LUT) derivatives. In this work, a glycerol-based ultrasound-assisted extraction method was developed and optimized for in total phenol (TP) and LUT content, as well as antiradical activity (RSA). The best conditions (glycerol content, temperature, plant material weight, and ultrasonication power) for the preparation of J. montana extracts richest in TP (OPT-TP), LUT (OPT-LUT), and having the best RSA (OPT-RSA) were determined. Furthermore, numerous natural deep eutectic solvents (NADES), containing proline, glycerol, betaine, urea, and glucose were prepared and used for the extraction of J. montana. Contents of TP, LUT, and RSA in the prepared extracts were established. Antioxidant and cosmeceutical activity of the prepared extracts was tested. The OPT-TP, OPT-LUT, and OPT-RSA, as well as the most efficient NADES-based extract, PG-50-TP, were excellent antioxidants and Fe2+ ion chelators. In addition, they were potent inhibitors of collagenase and hyaluronidase, as well as good significant anti-elastase and -lipoxygenase activity. The observed antioxidant- and enzyme-inhibiting activity of J. montana extracts prepared using environmentally friendly methods and non-toxic solvents makes them promising ingredients of cosmeceutical products.

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Section: Resultsmentioning

confidence: 99%

Glycerol and Natural Deep Eutectic Solvents Extraction for Preparation of Luteolin-Rich Jasione montana Extracts with Cosmeceutical Activity

et al. 2022

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“…Recent studies have found that APG has good anticoagulant and hemostatic effects. 90,91 In human serum albumin, APG can replace warfarin, a widely used anticoagulant drug but with a narrow therapeutic window. This shows the anti-coagulant potential of APG.…”

Section: Anticoagulationmentioning

confidence: 99%