Chemical constituents and their biological activities from Taunggyi (Shan state) medicinal plants

Abstract

Medicinal plants are essential aspects of readily available primary healthcare remedies. Phytochemical constituents of medicinal plants cover a broad variety of chemical fields to explore medicines. This review highlights selected empirical data on traditional uses, phytochemistry, and pharmacological properties of Taunggyi medicinal plants, Andrographis paniculata, Physalis peruviana, and Cassia fistula. Historically, these plants have been used for many infections and diseases in Taunggyi. More than 361 chemical compounds have been isolated and identified from the selected plants. Some of the chemical constituents have substantial pharmacological properties. It is clear that these herbs have significant potential for useful natural supplements in many contemporary diseases. Thus, the aim of this review compiles an ethnobotanical survey and documentation of medicinal plants in Taunggyi (Myanmar). This review will also inspire Myanmar researcher's to further investigate the potential of these plants in their future work into new compound and new drugs.

Pharmacological Activities of Rhododendron afghanicum; an Endemic Species of Khyber Pakhtunkhwa, Pakistan

“…Significant mortality of brine shrimps was found at 10 g/ml, while highly significant findings were seen for all samples at 100 and 1000 g/ml as recorded in (Table 3). Similar studies have been described by other workers such as [20,21,22] on Andrographis paniculata, Physalis peruviana and Cassia fistula respectively having strong cytotoxic effects. These findings showed that this species may contain certain active components having significant therapeutic potentail.…”

Andrographis paniculata (Burm. f.) Wall. ex Nees: An Updated Review of Phytochemistry, Antimicrobial Pharmacology, and Clinical Safety and Efficacy

“…The identified secondary metabolites included 78 ent-labdane diterpenoids, 41 flavonoids, eight quinic acid derivatives, four xanthones, five rare noriridoids, three steroids and three other compounds (Supplementary Table S2). A recent study also reported a similar number of unique secondary metabolites [169]. Among these compounds, about 80 compounds showed different types of pharmacological activities, including antibacterial [109,139,[170][171][172][173][174][175], anti-biofilm [88,176], antiviral (i.e., chikungunya virus [91], Anti-HIV [177][178][179], anti-influenza [99,180], Herpes simplex virus 1 [83,99,181], dengue virus serotype 1 [92][93][94]182], anti-Epstein Barr virus [97], pestivirus and flavivirus [90], human papillomavirus type 16 [96]), anti-fungal [109,183], antiparasitic (i.e., antimalarial [95,184,185], anti-Leishmaniasis [98]), antiproliferative [85][86][87]120,122,124,127,128,177,…”

Estimation the protective role of Andrographis paniculata aqueous extracts on nephrotoxicity in male rabbits treated with butylated hydroxytoluene (BHT)

“…It was also used in ancient traditional medicine around the world (Sharma & Sharma, 2018), Andrographis contains a high percentage of saponins, alkaloids, terpenoids, phenols, flavonoids, and tannins (Nagajothi et al, 2018). About 135 compounds have been isolated from this plant, including 40 flavonoids, 82 terpenes, and three steroids, in addition to 10 other compounds in the plant (Aminah et al, 2021). Andrographolide contains many phytochemicals, Including andrographolide.…”