Chemical constituents and bioactivity of Piper sarmentosum

Rukachaisirikul, Thitima; Siriwattanakit, Puttan; Sukcharoenphol, Kanchanawadee; Wongvein, Chanika; Ruttanaweang, Phongpan; Wongwattanavuch, Phaopong; Suksamrarn, Apichart

doi:10.1016/j.jep.2004.01.022

Cited by 123 publications

(89 citation statements)

References 19 publications

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“…Seven isolated compounds-pellitorine, sarmentine, 1-piperettyl pyrrolidine, pellitorine, guineensine, brachyamide B and 1-(3,4-methylenedioxyphenyl)-1E-tetradecene-from hexane extract of fruit have exhibited antimycobacterial activity, MIC ranging 25-200 µg/mL (Rukachaisirikul et al, 2004). There are other two reports of antimycobacterial activity whereby ethanol extracts of various parts of the plant have shown promising activity and synergistic effect on the activity of isoniazid (Hussain et al, 2008b(Hussain et al, , 2009a.…”

Section: Antibacterial Activitiesmentioning

confidence: 99%

“…Subcutaneous administration of aqueous extracts of the plant has exhibited a dose-dependent anti-nociceptive and antiinflammatory activity (Rukachaisirikul et al, 2004). Vaghasiya et al (2007) have also investigated the antiinflammatory activity of methanol extracts of leaves at a dose 300 mg/kg and noticed 47.41 and 24.78% reduction in paw edema in 1 and 3 h, respectively.…”

Section: Anti-inflammatory and Antipyretic Activitymentioning

confidence: 99%

“…In a comparative study, chloroform and methanol extracts of leaves have shown complete inhibition of plasmodium in 48 h at a doses 0.05 and 0.08 mg/mL, respectively (Najib, 1999). Rukachaisirikul et al (2004) have reported that two isolated amides, sarmentine and 1-piperettyl pyrrolidine, from hexane extracts of fruit have also exhibited antiplasmodial activity with IC 50 18.9 and 6.5 µg/mL, respectively.…”

Section: Antiprotozoal Activitymentioning

confidence: 99%

See 2 more Smart Citations

A review of the literature and latest advances in research ofPiper sarmentosum

Hussain

Hashmi

Latif

et al. 2012

Pharmaceutical Biology

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Section: Antibacterial Activitiesmentioning

confidence: 99%

Section: Anti-inflammatory and Antipyretic Activitymentioning

confidence: 99%

Section: Antiprotozoal Activitymentioning

confidence: 99%

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A review of the literature and latest advances in research ofPiper sarmentosum

Hussain

Hashmi

Latif

et al. 2012

Pharmaceutical Biology

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“…The plant has been investigated for a number of pharmacological activities such as hypoglycemic [2], anti-amoebic [3], antibacterial [4], neuromuscular blocking [5], anti-malarial [6], antioxidant [7], anti-tuberculosis [8], anticancer [9] and anti-angiogenic activity [10].…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Determination of Two Isomers of Asarone in <i>Piper sarmentosum</i> Roxburgh (Piperaceae) Extracts using Different Chromatographic Columns

Hamil¹,

Memon²,

Majid³

et al. 2016

Trop. J. Pharm Res

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“…Several plants of this genus are largely used in folk medicine in several parts of the world and have been reported to produce compounds with diverse biological and pharmacological properties. [2][3][4][5][6][7][8] Many Piper species are aromatic and as a consequence the chemical composition of the essential oils of several of them has been the subject of incessant studies, revealing a diverse range of volatile components, including monoterpenes, sesquiterpenes, arylpropanoids, aldehydes, ketones and long chain alcohols. [9][10][11][12][13][14][15][16] Pursuing the determination of the chemical composition of essential oils from aromatic and medicinal plants from Northeast of Brazil flora, especially from the State of Ceará, we are reporting now the results of the investigation of four Piper species: P. dilatatum L.C.…”

Section: Introductionmentioning

confidence: 99%

Leaf essential oils of four Piper species from the State of Ceará - Northeast of Brazil

Cysne

Canuto

Pessoa

et al. 2005

J. Braz. Chem. Soc.

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Os óleos essenciais obtidos por hidrodestilação das folhas de quatro espécies de Piper (P. arboreum, P. crassinervium, P. dilatatum and P. tuberculatum), coletadas no estado do Ceará, foram analisados por CG-EM. Os rendimentos dos óleos, calculados sobre o peso do material fresco, variaram entre 0,03 -0,11% (p/p). Os óleos foram caracterizados pela presença de mono-e sesquiterpenos, exceto o óleo de P. arboreum, no qual foram identificados apenas sesquiterpenos. β-Elemeno (0,58-3,03%), (E)-cariofileno (2,71-37,78%), germacreno D (3,43-11,81%), biciclogermacreno (2,83-25,07%) e δ-cadineno (0,52-2,44%) foram detectados em todas as amostras analisadas. Os monoterpenos majoritários identificados foram α-pineno (11,27%), β-pineno (20,01%), 1,8-cineol (10,81%) e linalol (28,61%) para P. crassinervium, e α-felandreno (22,53%) e ∆-3-careno (10,20%) para P. dilatatum. Biciclogermacreno (25,03 e 25,07%) para P. arboreum e P. dilatatum, (E)-nerolidol (11,12%) para P. arboreum, germacreno D (11,81%) para P. tuberculatum e (E)-cariofileno (10,26 e 37,78%) para P. dilatatum e P. tuberculatum, foram os principais sesquiterpenos. Este trabalho descreve, pela primeira vez, a composição química dos óleos essenciais de P. crassinervium e P. tuberculatum.The essential oils, obtained by hydrodistillation, from leaf samples of four Piper species (P. arboreum, P. crassinervium, P. dilatatum and P. tuberculatum), harvested at the State of Ceará, were analyzed by GC-MS. The oil yields ranged from 0.03 to 0.11% (w/w), on fresh weight basis. The oils were characterized by mono-and sesquiterpenes, except the oil of P. arboreum to which only sesquiterpenes were identified. β-Elemene (0.58-3.03%), (E)-caryophyllene (2.71-37.78%), germacrene D (3.43-11.81%), bicyclogermacrene (2.83 and 25.07%) and δ-cadinene (0.52-2.44%) were detected in all oil samples. The major identified monoterpenes were α-pinene (11.27%), β-pinene (20.01%), 1,8-cineole (10.81%) and linalool (28.61%) for P. crassinervium and, α-phellandrene (22.53%) and ∆-3-carene (10.20%) for P. dilatatum. The major sesquiterpenes were bicyclogermacrene (25.03 and 25.07%) for P. arboreum and P. dilatatum, (E)-nerolidol (11.12%) for P. arboreum, germacrene D (11.81%) for P. tuberculatum and, (E)-caryophylene (10.26 and 37.78%) for P. dilatatum and P. tuberculatum. To the best of our knowledge this is the first report about the chemical composition of the leaf essential oils of P. crassinervium and P. tuberculatum.

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Chemical constituents and bioactivity of Piper sarmentosum

Cited by 123 publications

References 19 publications

A review of the literature and latest advances in research ofPiper sarmentosum

A review of the literature and latest advances in research ofPiper sarmentosum

Simultaneous Determination of Two Isomers of Asarone in <i>Piper sarmentosum</i> Roxburgh (Piperaceae) Extracts using Different Chromatographic Columns

Leaf essential oils of four Piper species from the State of Ceará - Northeast of Brazil

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