A review of the literature and latest advances in research of<i>Piper sarmentosum</i>

Hussain, Khalid; Hashmi, Furqan K.; Latif, Ayesha; Ismail, Zhari; Sadikun, Amirin

doi:10.3109/13880209.2011.654229

Cited by 34 publications

(21 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is known as daun kaduk, wild pepper, wild betel or sirih duduk in Malaysia; karuk or sirih tanah in Indonesia; cha plu in Thailand; bo la lot in Vietnam; phak i leut in Laos and jia ju, xi ye qing wei teng or qing ju in China. The plant easily grows in shady areas (Hussain et al 2012). It is glabrous and creeping with 40-50 cm height of procumbent branches (Rahman et al 2016).…”

Section: Introductionmentioning

confidence: 99%

Piper sarmentosum as an Antioxidant: A Systematic Review

Ismail

Chua²,

Aminuddin³

et al. 2018

JSM

View full text Add to dashboard Cite

Piper sarmentosum (PS) is an herb with various medicinal properties. The antioxidant activity of PS contributes to many of its pharmacological effects such as anti-hypertension, anti-cancer and anti-diabetes. This systematic review provides information regarding the antioxidant activity of PS. The review was conducted systematically to identify relevant published articles on the antioxidant activity of PS. The collected data was based on the searched articles through PubMed, Science Direct and Scopus databases between the years 1946 until March 2018. Only articles written in English and related to antioxidant activity of PS were included in this review. Based on the literature searched, 130 potential articles were identified and 19 articles met the inclusion criteria. Ten studies related to chemical assays, five studies combined in vivo animal and chemical assays, three studies combined chemical assays and in vitro studies and a single study combined chemical assay, in vitro and in vivo studies were included in this review. All studies showed positive effects of PS against oxidation, indicating the potential of PS as a source of natural antioxidant.

show abstract

Section: Introductionmentioning

confidence: 99%

Piper sarmentosum as an Antioxidant: A Systematic Review

Ismail

Chua²,

Aminuddin³

et al. 2018

JSM

View full text Add to dashboard Cite

show abstract

“…In Malaysia and Indonesia, this plant is used in traditional medicine for treating toothache, pleuritis, asthma, diabetes, hypertension, joint pain and fungal infections. Phytochemicals of Ps indicate that the methanol extracts of this plant contain naringenin, a flavonoid [ 23 , 29 , 54 ]. Flavonoids are known to reduce bone loss and increase bone strength in ovariectomised rats [ 55 ].…”

Section: Discussionmentioning

confidence: 99%

The Role of Piper sarmentosum Aqueous Extract as a Bone Protective Agent, a Histomorphometric Study

Asri

Soelaiman

Moklas

et al. 2020

IJMS

View full text Add to dashboard Cite

Glucocorticoids are one of the causes of secondary osteoporosis. The aqueous extract of Piper sarmentosum contains flavonoids that possess antioxidant effects. In this study, we determined the effects of aqueous Piper sarmentosum leaf extract on structural, dynamic and static histomorphometric changes from osteoporotic bones of rats induced with glucocorticoids. Thirty-two Sprague-Dawley rats were divided equally into four groups—Sham control group given vehicles (intramuscular (IM) olive oil and oral normal saline); AC: Adrenalectomised (Adrx) control group given IM dexamethasone (DEX) (120 μg/kg/day) and vehicle (oral normal saline); AP: Adrx group administered IM DEX (120 μg/kg/day) and aqueous Piper sarmentosum leaf extract (125 mg/kg/day) orally; and AG: Adrx group administered IM DEX (120 μg/kg/day) and oral glycyrrhizic acid (GCA) (120 mg/kg/day). Histomorphometric measurements showed that the bone volume, trabecular thickness, trabecular number, osteoid and osteoblast surfaces, double-labelled trabecular surface, mineralizing surface and bone formation rate of rats given aqueous Piper sarmentosum leaf extract were significantly increased (p < 0.05), whereas the trabecular separation and osteoclast surface were significantly reduced (p < 0.05). This study suggests that aqueous Piper sarmentosum leaf extract was able to prevent bone loss in prolonged glucocorticoid therapy. Thus, Piper sarmentosum has the potential to be used as an alternative medicine against osteoporosis and osteoporotic fractures in patients undergoing long-term glucocorticoid therapy.

show abstract

“…monnieri (Srivastava et al, , ), Cassia angustifolia (Goppel and Franz, ), Carum carvi (Sachan et al, ), C . officinalis (Hiegl and Franz, ), Crataegus oxyacantha (Bilia et al, ), Hieracium pilosella (Bilia et al, ), Mentha piperita (Sachan et al, ), Piper longum (Srivastava et al, ), Piper sarmentosum (Hussain et al, ), Sesbania grandiflora (Dwivedi and Gupta, ), Solanum nigrum (Hiegl and Franz, ), Verbena officinalis (Goppel and Franz, ) and W . somnifera (Patil et al, ).…”

Section: Conformity and Contravention With Recommended Stability Condmentioning

confidence: 99%

“…Among these, the studies by Hussain et al . () and Bankoti et al () have actually followed the regulatory guidelines for storage condition and duration.…”

Section: Conformity and Contravention With Recommended Stability Condmentioning

confidence: 99%

Stability Testing of Herbal Drugs: Challenges, Regulatory Compliance and Perspectives

et al. 2016

View full text Add to dashboard Cite

Stability testing is an important component of herbal drugs and products (HDPs) development process. Drugs regulatory agencies across the globe have recommended guidelines for the conduct of stability studies on HDPs, which require that stability data should be included in the product registration dossier. From the scientific viewpoint, numerous chemical constituents in an herbal drug are liable to varied chemical reactions under the influence of different conditions during its shelf life. These reactions can lead to altered chemical composition of HDP and consequently altered therapeutic profile. Many reports on stability testing of HDPs have appeared in literature since the last 10 years. A review of these reports reveals that there is wide variability in temperature (-80 to 100 °C), humidity (0-100%) and duration (a few hours-36 months) for stability assessment of HDPs. Of these, only 1% studies are conducted in compliance with the regulatory guidelines for stability testing. The present review is aimed at compiling all stability testing reports, understanding key challenges in stability testing of HDPs and suggesting possible solutions for these. The key challenges are classified as chemical complexity and biochemical composition variability in raw material, selection of marker(s) and influences of enzymes. Copyright © 2016 John Wiley & Sons, Ltd.

show abstract

A review of the literature and latest advances in research ofPiper sarmentosum

Cited by 34 publications

References 39 publications

Piper sarmentosum as an Antioxidant: A Systematic Review

Piper sarmentosum as an Antioxidant: A Systematic Review

The Role of Piper sarmentosum Aqueous Extract as a Bone Protective Agent, a Histomorphometric Study

Stability Testing of Herbal Drugs: Challenges, Regulatory Compliance and Perspectives

Contact Info

Product

Resources

About