Stability Testing of Herbal Drugs: Challenges, Regulatory Compliance and Perspectives

Bansal, Gulshan; Suthar, Nancy; Kaur, Jasmeen; Jain, Astha

doi:10.1002/ptr.5618

Cited by 25 publications

(17 citation statements)

References 72 publications

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“…12 Other study conducted in Jordan among pharmacists documented that the majority of pharmacists believed that advanced educational courses about pharmacological and toxic effects of herbal medicine products were essential. 13 In 2010, other study conducted among the pharmacists in Abu Dhabi reported that the use of herbal medicine is more prevalent, and they were aware of the uses of these products, but they had similar results regarding herbal side effects and herbal-drug interactions. 14 Another study that opposed our study finding had previously evaluated the prevalence of using herbal medicine among pharmacist was at Kuwait in 2007 recorded that most pharmacists preferred herbal products instead of conventional pharmaceuticals.…”

Section: Discussionmentioning

confidence: 99%

The Prevalence, Attitude and Awareness of Herbal Medicine Products Use Among Pharmacy Practitioner in Jordan

Younis¹

2019

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Conventional medicine is any agent that largely used by most healthcare professionals to treat any disease that infects humans and animals or to decrease the severity of any condition or diagnosis or prevention. 1 Herbal medicine considered to be the oldest form of healing and treating different diseases. The history of herbal medicine is part of the history of medicine itself and herbal knowledge came to Europe from the Middle East during the crusades. Herbal medicine is classified as 'complementary' or 'alternative' in most countries, it stills the only type of medicine that widely available to much of the world's population. Herbal medicines have been utilized in most traditional cultures and have had a vital impact on many systems, including Ayurvedic (Indian) medicine, traditional Chinese medicine, and conventional medicine. There was a written record of Egyptian, Roman, Persian and Hebrew cultures reported that they were used herbs to cure every complaint and diseases. 2 Although herbal medicine is classed as 'alternative' or 'complementary' in most Western countries, it remains the only form of medicine widely available to much of the world's population. Although herbal medicine is classed as 'alternative' or 'complementary' in most Western countries, it remains the only form of medicine widely available to much of the world's population. 3 These medicines play a major part in the pharmaceutical market in all world contourites. Many of these products are currently sold in pharmaceutical forms such as tablets, capsules, syrups, etc.… prescribed by physicians or over the counter for curing different conditions. It became a good business for several companies to produce and market safe and effective herbal preparations. Most patients go to complementary medicines produced from a natural herbal source because they believe that they are safer, more effective and have fewer side effects than traditional synthetic medicine. In the other hand, consumers believed ABSTRACT Background: There has been a universal increase in the use of herbal medicine products (HMPs). Herbal medicine considered to be the oldest form of healing and treating different diseases. Objective: The aim of this study is to determine the prevalence, attitude of HMPs use and awareness among pharmaceutical practitioner in Jordan. Methods: A descriptive cross-sectional survey was conducted using a self-administered questionnaire on a sample of 230 Jordanian pharmacy practitioner (pharmacist and pharmacy assistant), within 90 different private pharmacies in different cities of Jordan during the period of 6 months in the mid of 2018. The survey questionnaire included: the socio-demographic characteristics of participants, the source of information of the use of the HMPs, the attitude towards the use and safety of the HMPs and their combination with conventional drugs. Results: Out of 230 pharmacy practitioners interviewed in this study, the utilization rate of the HMPs use was just 41.7%. A large number of practitioners (58.3%) preferred conventiona...

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Section: Discussionmentioning

confidence: 99%

The Prevalence, Attitude and Awareness of Herbal Medicine Products Use Among Pharmacy Practitioner in Jordan

Younis¹

2019

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“…After a few months, the sample analyzed associated clarity, pH, viscosity, drug content, rheological, and in vitro dissolution. The storage conditions and the length of the study chosen should be sufficient to cover the storage, shipment, and subsequent use [121,122].…”

Section: Stability Studiesmentioning

confidence: 99%

A Comprehensive Review on in Situ Gels

Padmasri

Nagaraju

Prasanth³

2020

Int J App Pharm

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The current review on in situ gelling systems becomes one of the most popular and prominent. It had a tremendous potential advantage of delivery systems due to many benefits like easy to use simple manufacturing; improve both adherence and patient comfort by minimizing the frequency of drug administration by its unique characteristics feature of sol to gel transition. It also provides in situ gelling nanoemulsions, nanosphere, microspheres, and liposomes. The drawbacks associated with conventional systems of both solutions and gels, such as accurate dosing, ease of administration overcome by using in situ gelling systems. This review focused on definitions, types, advantages, disadvantages, polymers used, and suitable characteristics of polymers, including the preparation of in situ gels covered in the introduction. Approaches, applications, and evaluation of in situ gels were explained with examples.

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“…The WHO (2006) has also recommended for stability studies on herbal drugs and finished herbal formulations. The stability testing of herbal drugs, challenges, regulatory compliance and perspectives has been recently reviewed (Bansal, Suthar, Kaur, et al, 2016). In India, for a phytopharmaceutical drug, there is a provision in Drugs and Cosmetics Rules, 1945 (notified vide GSR 918(E) (2015), Ministry of Health and Family Welfare) for requirement of stability data.…”

Section: Stability Testing Of Herbal Drugsmentioning

confidence: 99%

Current Status of Herbal Drug Standards in the Indian Pharmacopoeia

Prakash

Srivastava

Ray

et al. 2017

Phytotherapy Research

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The benefits of herbal drugs were well understood way back. They have been used for the promotion of health and medical purposes – in disease conditions. It is a conventional belief that herbal drugs have no side effects, are cheaper and locally available. Among Indian systems of medicines, herbs/herbal formulations are used to a larger extent. The quality control of the marketed herbs/herbal formulations is important for acquiring optimum therapeutic benefit as well as for expanding global outreach. Therefore, herbal drug standards are important. Reference standards, the Indian Pharmacopoeia Reference Substances especially the botanical reference substances and the phytochemical reference substances are required for comparison of quality of herbal drugs. The Indian Pharmacopoeia Commission has initiated the process of providing Indian Pharmacopoeia Reference Substances to the stakeholders. Therefore, this article provides an overview of the history and the status of herbal drug standards in the current and forthcoming issues of Indian Pharmacopoeia. In Indian Pharmacopeia, efforts have been made for the harmonization of standards with international counterparts wherever possible. Copyright © 2017 John Wiley & Sons, Ltd.

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Stability Testing of Herbal Drugs: Challenges, Regulatory Compliance and Perspectives

Cited by 25 publications

References 72 publications

The Prevalence, Attitude and Awareness of Herbal Medicine Products Use Among Pharmacy Practitioner in Jordan

The Prevalence, Attitude and Awareness of Herbal Medicine Products Use Among Pharmacy Practitioner in Jordan

A Comprehensive Review on in Situ Gels

Current Status of Herbal Drug Standards in the Indian Pharmacopoeia

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