Characterizations of nano-zinc doped hydroxyapatite to use as bone tissue engineering

Abdel-Ghany, Basma E.; Abdel-Hady, Bothaina M; El-Kady, Abeer M.; Beheiry, Hanan H.; Guirguis, Osiris W.

doi:10.12989/amr.2015.4.4.193

Cited by 5 publications

(5 citation statements)

References 18 publications

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“…For HAP powder, there were crystalline peaks at 2θ = 26.2°, 30.02°, 32.32°, 35.68°, 45.28°, and 50.42°, which were assigned to (002), (211, 112), (300), (130), and (222), respectively, and were attributed to the apatite composition and matched the ICDD standard for HA (JCPDS No. 76‐0694) 61 . The HAP‐CS scaffold showed the same predominant HAP peaks.…”

Section: Resultsmentioning

confidence: 85%

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Hydroxyapatite/hyperbranched polyitaconic acid/chitosan composite scaffold for bone tissue engineering

et al. 2023

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In this study, a promising modified composite scaffold (hydroxyapatite/hyperbranched polyitaconic acid/chitosan) was synthesized for bone tissue engineering. Novel hyperbranched polyitaconic acid was prepared through the polymerization of itaconic acid using reversible addition fragmentation chain transfer using a macro‐RAFT agent. The chemical structure of the prepared hyperbranched polyitaconic acid was characterized by FTIR and 1HNMR and was subsequently embedded into hydroxyapatite/chitosan composite. The obtained modified composite scaffold was evaluated by characterizing its porosity, mechanical properties, bioactivity and cytotoxicity. The results showed that the modified composite scaffold had higher mechanical strength (i.e., 0.56 ± 0.03 MPa) in comparison to chitosan/hydroxyapatite scaffold only (i.e., 0.31 ± 0.01 MPa) and also showed higher bioactivity. In addition, the modified composite scaffold (HAP/HBP‐RAFT‐PI/CS) showed anticancer properties and enhanced human skin fibroblasts proliferation.

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Section: Resultsmentioning

confidence: 85%

“…76-0694). 61 The HAP-CS scaffold showed the same predominant HAP peaks. In the case of HAP/HBP-RAFT-PI/CS, a different peak appeared at 2θ = 20.8 due to the presence of HBP-RAFT-PI which agreed with the previously reported results.…”

Section: Characterization Of Cs Hap Hap/cs and Hap/hbp-raft-pi/cs Sca...mentioning

confidence: 89%

Hydroxyapatite/hyperbranched polyitaconic acid/chitosan composite scaffold for bone tissue engineering

et al. 2023

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“…Results revealed that the “c” lattice parameter decreased with increasing ZnO fraction, while the “a” lattice parameter enhanced with increasing ZnO fraction upon 8 wt% and consequently decreased. Such behavior was due to the difference in the ionic radius of Ca and Zn . The zinc ions could be sited in three positions in the structure of FA consisting of Ca(I), Ca(II) and P positions.…”

Section: Resultsmentioning

confidence: 99%

“…Such behavior was due to the difference in the ionic radius of Ca and Zn. 32 The zinc ions could be sited in three positions in the structure of FA consisting of Ca(I), Ca(II) and P positions. While Ca(I) atoms formed an octahedral structure with O 2− atoms, Ca(II) atoms with surrounding O 2− and P 5− ions organized a tetrahedral structure.…”

Section: Characterization Of Fa-zno Nanopowdermentioning

confidence: 99%

In situ synthesis of fluorapatite‐ZnO nanocomposite powder via mechanical alloying for biomedical applications

Salehi

Kharaziha

Salehi

et al. 2020

Int J Applied Ceramic Tech

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This research aimed to synthesize of fluorapatite(FA)–ZnO (FAZ) nanocomposite powder using a one‐step mechanical alloying process without any post‐calcification process. Furthermore, the role of various concentrations of ZnO (0, 4, 8, 11, and 15 wt.%) on the chemical and biological characteristics of FA was examined. Our research confirmed the successful synthesize of FAZ nanopowders with irregular‐shaped particles and particle size of 38‐52 nm. The crystallinity, crystallite size, and c‐axes parameter of FA decreased with increasing ZnO content. Moreover, while all FAZ powders revealed superior bioactivity than FA, FA‐8 wt.% ZnO nanopowder significantly enhanced MG63 cell proliferation. Besides, between various samples, FA‐11 wt.% ZnO nanopowder revealed drastically greater antibacterial activity. It could be concluded that the in‐situ synthesis of FAZ powder meaningfully improved the biological activity of FA making it a promising coating for orthopedic and dental implants.

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“…TCP/silver/PLGA scaffolds (TCP/Ag/PLGA) with a proven prolonged antibacterial effect against E. coli [ 151 ] have also been reported. Some researchers developed HAp scaffolds with Ag/TiO 2 /PA66 [ 154 ], Sr, Zn [ 164 , 177 ], or Ti6Al4V (pTi), CS and selenium (Se) (pTi/CS/HAp-Se) [ 186 ]. They observed osteoblast proliferation, tumor cell growth inhibition and bacterial viability with pTi/CS/HAp-Se scaffolds.…”

Section: Antimicrobial Scaffolds For Tissue Engineeringmentioning

confidence: 99%

Scaffolds in the microbial resistant era: Fabrication, materials, properties and tissue engineering applications

Serrano‐Aroca

Cano-Vicent

Serra

et al. 2022

Materials Today Bio

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Characterizations of nano-zinc doped hydroxyapatite to use as bone tissue engineering

Cited by 5 publications

References 18 publications

Hydroxyapatite/hyperbranched polyitaconic acid/chitosan composite scaffold for bone tissue engineering

Hydroxyapatite/hyperbranched polyitaconic acid/chitosan composite scaffold for bone tissue engineering

In situ synthesis of fluorapatite‐ZnO nanocomposite powder via mechanical alloying for biomedical applications

Scaffolds in the microbial resistant era: Fabrication, materials, properties and tissue engineering applications

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