Changes in serum biochemical and lipid profile, and fatty acid composition of breast meat of broiler chickens fed supplemental grape seed extract

Abstract

A study was conducted to evaluate the changes in serum biochemical and lipid profile, and fatty acid composition of breast meat of broiler chickens fed supplemental grape seed extract (GSE). A total of 240 1-day-old male broiler chickens were randomly allocated to 4 groups, each consisting of 4 replicate pens having 15 birds/replicate pen. One group served as control group fed basal diets and other groups received 100, 200, and 400 ppm GSE supplemented to the basal diets. Liver weight was greater in broilers fed 200 ppm GSE compared to the other groups (P = 0.004, L = 0.024, C = 0.010). Serum AST and ALT levels decreased (P < 0.001) whereas ALP levels increased with increasing dietary GSE levels (P < 0.001). Serum albumin and total protein levels were lower in control in comparison with other groups (P < 0.001). Serum cholesterol, triglyceride, and LDL levels declined (P < 0.001) while HDL levels increased with increasing supplemental GSE levels (P < 0.001). MUFA levels were greater in breast meat of broiler chickens fed diets supplemented with 100 ppm GSE. On the other hand, PUFA (including n-3 and n-6) were greater in broiler chickens fed control diets or 400 ppm GSE supplemented diets. In general, essential fatty acids such as α-linolenic acid (n-3 C18:3), arachidonic acid (n-6 C20:4), eicosapentaenoic acid (n-3 C20:5), and docosahexaenoic acid (n-3 C22:6) were greater in breast meat of broiler chickens fed supplemental GSE (100, 200, or 400 ppm) while overall UFA concentration in breast meat remained unaffected. In conclusion, findings of this study suggest that dietary supplementation of up to 400 ppm GSE in broilers may improve serum biochemical and lipid profile. It may also improve the fatty acid composition of breast meat to varying extent despite no effect on overall UFA concentration.

Dietary Phytogenic Extracts Favorably Influence Productivity, Egg Quality, Blood Constituents, Antioxidant and Immunological Parameters of Laying Hens: A Meta-Analysis

“…Meanwhile, HDL transports cholesterol from peripheral tissues to the liver before excreting it via the bile pathway [ 65 ]. In addition, polyphenols induce the expression of the cholesterol enzyme 7-alpha hydroxylase, which controls the bile synthesis and homeostasis of cholesterol and inhibits the activity of hydroxyl-3-methyl-glutaryl-CoA as a limiting enzyme for cholesterol synthesis [ 66 , 67 ]. Moreover, egg cholesterol deposition is closely related to plasma triglyceride level, total cholesterol, and LDL [ 68 ].…”

Growth Performance, Histological Changes and Functional Tests of Broiler Chickens Fed Diets Supplemented with Tribulus Terrestris Powder

“…The analysis of TT powder was performed in duplicate to determine the content of nutrients (dry matter, crude protein, ash, and total fiber) according to the methods of AOAC [ 27 ]. The fatty acids composition of TT powder was performed using the method of extraction with a mixture of chloroform and methanol, and then the total fat (g/100 g of TT) was calculated [ 28 ]. Fatty acid profiles were analyzed using a gas chromatograph mass spectrometer (GC-MS) [ 29 ].…”

Aceite esencial de orégano (Lippia origanoides) mejora parámetros productivos y metabólitos sanguíneos en lechones

“…La glucosa es un metabolito indispensable en los procesos fisiológicos de animales monogástricos, ya que representa una fuente de energía esencial para el mantenimiento y desarrollo de tejidos (Thongsong et al, 2019). Sin embargo, factores asociados al desarrollo de las vellosidades intestinales y la expresión de transportadores intestinales de glucosa afectan la absorción de dicho nutriente, y por tanto su disponibilidad a nivel sanguíneo, afectando el crecimiento de los animales (Gao et al, 2020;Karadağoğlu et al, 2020). Estudios realizados en aves y cerdos respaldan los resultados presentados en el cuadro 4, pues se ha reportado que el uso de AEO en la dieta incrementa las concentraciones séricas de glucosa en comparación al uso de antibióticos promotores del crecimiento (Patiño et al, 2019).…”

“…La disminución en los niveles séricos de colesterol y triglicéridos libres está directamente relacionada con una menor tasa de problemas cardiacos (Madrid et al, 2018) y una menor deposición de grasa muscular en los animales (Karadağoğlu et al, 2020), lo cual se verá reflejado en una menor tasa de mortalidad en granja y una mejor aceptación del producto final por parte de los consumidores. Acorde a los resultados encontrados en la…”

“…Dicha disminución ha sido asociada a un incremento en la concentración sérica de lipoproteínas de alta densidad (HDL) que facilitan el transporte de colesterol y triglicéridos libres nuevamente al hígado (Li et al, 2017), y una consecuente reducción en la concentración de lipoproteínas de baja densidad (LDL) inducida bajo el uso de AEO (Madrid et al, 2018). Además, ha sido propuesto que los fenoles presentes en los aceites esenciales tienen la capacidad de regular la homeostasis del colesterol mediante un aumento en la expresión de la enzima colesterol 7 alfa-hidrolasa implicada en la síntesis de sales biliares, y la inhibición en la actividad de la 3-hidroximetil glutaril-COA cuya función es limitante en la síntesis de colesterol (Karadağoğlu et al, 2020).…”