Castor polyurethane used as osteosynthesis plates: microstructural and thermal analysis

Abstract

Bone fractures to be corrected need stabilization of their extremities, which is achieved with the use of plates and screws. This research aimed to produce castor bean polyurethane (Ricinus communis), to make resorbable plate, structural and thermal analysis. The production was made by the glycerolysis of the triglycerides present in the oil, after addition of polyol/glycerol and hexamethylene diisocyanate (HDI) to form urethane structures, with and without addition of hydroxyapatite. The characterization was by FTIR spectroscopy, scanning electron microscopy (SEM), X-ray diffraction, differential scanning calorimetry and thermogravimetry. Plates with dimensions of 40 mm X 10 mm X 2 mm were obtained. The SEM showed flat and homogeneous surface. DRX analysis showed the semi-crystallinity of the biomaterial. Glass transition and thermal stability up to 50 °C were observed, followed by thermal decomposition up to 450 °C. The produced polyurethane showed it is possible to be applied in the manufacture of plate.

Polyurethane derived from castor oil monoacylglyceride (Ricinus communis) for bone defects reconstruction: characterization and in vivo testing

“…1c ) between 1739 and 1736 cm −1 , which does not appear in the glycerol spectrum. The absorption bands at 1241 cm −1 and 1047 cm −1 denote C–O and C–C coupling, present in glycerol and monoglyceride [ 15 ]. Highlighted in Fig.…”

“…Hexamethylene diisocyanate (HDI) was added to the monoacylglyceride to obtain polyurethane after the curing process occurred. HDI was chosen because it is less toxic and does not contain benzene, and contributes to improving its properties [ 15 ]. Obtained by a different method, the polyurethane produced by Poliquil® is marketed under the name of Ricinus Bone Compound (COR).…”

“…We have obtained the MAG and polyurethane as described by Cunha and coworkers [14], Moura Neto and coworkers [15], and Nascimento and coworkers [16].…”

“…The reaction lasted for 5 h and occurred in the absence of solvent, following a stoichiometric ratio of 1: 4 (MAG: HDI). The ratios used here have been chosen based on our previous studies [14][15][16], in which a broader review was possible.…”

“…The FTIR spectra of MAG and polyurethane samples were obtained in a Thermo Fisher SCIENTIFIC NICOLET iS5 spectrophotometer with a purge pump and wavelength between 400 and 4000 cm −1 , 128 accumulated scans, 4 cm −1 resolution, in ATR, in Transmittance module. The method has been used to verify the curing reaction of polyurethane and free isocyanate functional groups (NCO) after the response [14][15][16][17]. The TG/DTG curves were obtained simultaneously in the SD Instruments Q 600, from TA Instruments, using a heating rate of 10°C/min, between 25°C and 600°C, in N2 atmosphere, with a sample mass of 10 mg [14].…”