Cardiovascular effects of an aqueous fraction of the ethanol extract of the leaves of Cissampelos Eichl. in the rat

Medeiros, Isac A.; Pires, S.L.S.; Almeida, Reinaldo Nóbrega de; Thomas, George P.

doi:10.1016/s0944-7113(98)80004-4

Cited by 6 publications

(3 citation statements)

References 15 publications

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“…The results has demonstrated that the extract significantly increased blood pressure of awake, unrestrained and anesthetized rats, and improved heart rate and contractility of isolated atrial perfusion formulations. [85] In Freitas et al's study, the extract of C. pareira root can alleviate cardiac dysfunction induced by Isoproterenol, and its mechanism may be related to the improvement of the calcineurin activity and free radical formation, and may also be related to the enhancement of antioxidant enzyme activity. [111]…”

Section: Cardiovascular Activitymentioning

confidence: 95%

“…After cardiac autonomic nerve block, the hypertensive effects produced by the ethanol extract of C. sympodialis (2 and 4 mg/kg) were enhanced. The study demonstrated that the ethanol extract of C. sympodialis markedly increased blood pressure in conscious anesthetized and unrestrained rats and improved contractility and heart rate in isolated perfused atrial preparations [85] . Vascular effects caused by milonine ( 60 ) of C. sympodialis dried leaves were also evaluated.…”

Section: Pharmacological Activitiesmentioning

confidence: 99%

“…The study demonstrated that the ethanol extract of C. sympodialis markedly increased blood pressure in conscious anesthetized and unrestrained rats and improved contractility and heart rate in isolated perfused atrial preparations. [85] Vascular effects caused by milonine (60) of C. sympodialis dried leaves were also evaluated. In normotensive rats, milonine injections produced tachycardia and hypotension.…”

Section: Antihypertensive Activitymentioning

confidence: 99%

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Phytochemical Constituents and Biological Activities of Plants from the GenusCissampelos

Yan

et al. 2021

Chemistry & Biodiversity

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Cissampelos is a significant genus comprising of approximately 21 species of the medicinal plants (Menispermaceae). The plants of this genus are used in traditional medicine for the treatment of various ailments such as asthma, arthritis, dysentery, hyperglycemia, cardiopathy, hypertension and other related problems. These plants are rich in bioactive dibenzylisoquinoline and aborphine as well as small amounts of other ingredients. In recent years, the chemical constituents and pharmacological activities of Cissampelos genus have been paid more and more attention due to their diversity. Herein, we compile the chemical constituents and biological activities on this genus, and summarize the 13C‐NMR data of the main bioactive ingredients. All information comes from scientific databases such as Google Scholar, PubMed, Sci‐Finder, ScienceDirect, Web of Science and CNKI. It provides valuable data for the future research and development of Cissampelos genus.

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Section: Cardiovascular Activitymentioning

confidence: 95%

Section: Pharmacological Activitiesmentioning

confidence: 99%

Section: Antihypertensive Activitymentioning

confidence: 99%

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Phytochemical Constituents and Biological Activities of Plants from the GenusCissampelos

Yan

et al. 2021

Chemistry & Biodiversity

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Anorectic and behavioural effects of chronic Cissampelos sympodialis treatment in female and male rats

Almeida

Melo‐Diniz

Medeiros

et al. 2005

Phytotherapy Research

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Male and female rats were treated daily for 13 weeks with an ethanol extract of Cissampelos sympodialis leaves (9, 45 and 225 mg[sol ]kg). The food consumption, body weight and behavioural effects in the open-field test were evaluated by weekly monitoring. The results showed that the extract chronic treatment in female rats (45 and 225 mg[sol ]kg) reduced significantly the food intake and the body weight, and produced several alterations in the open-field test. These findings indicate that repeated oral administration of the extract may produce a sex-dependent difference in anoretic and behavioural effects.

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Cissampelos genus: biological activities, ethnobotanical and phytochemical aspects

et al. 2020

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Cardiovascular effects of an aqueous fraction of the ethanol extract of the leaves of Cissampelos Eichl. in the rat

Cited by 6 publications

References 15 publications

Phytochemical Constituents and Biological Activities of Plants from the GenusCissampelos

Phytochemical Constituents and Biological Activities of Plants from the GenusCissampelos

Anorectic and behavioural effects of chronic Cissampelos sympodialis treatment in female and male rats

Cissampelos genus: biological activities, ethnobotanical and phytochemical aspects

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