BACKGROUND Corona Virus Disease 2019 (COVID-19) is spreading worldwide.Effective screening for patients is important to limit the epidemic. However, some defects make the currently applied diagnosis methods are still not very ideal for early warning of patients. We aimed to develop a diagnostic model that allows for the quick screening of highly suspected patients using easy-to-get variables. METHODSA total of 1,311 patients receiving severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleicacid detection were included, whom with a positive result were classified into COVID-19 group. Multivariate logistic regression analyses were performed to construct the diagnostic model. Receiver operating characteristic (ROC) curve analysis were used for model validation. RESULTS After analysis, signs of pneumonia on CT, history of close contact, fever, neutrophil-to-lymphocyte ratio (NLR), Tmax and sex were included in the diagnostic model. Age and meaningful respiratory symptoms were enrolled into COVID-19 early warning score (COVID-19 EWS). The areas under the ROC curve (AUROC) indicated that both of the diagnostic model (training dataset 0.956 [95%CI 0.935-0.977, P < 0.001]; validation dataset 0.960 [95%CI 0.919-1.0, P < 0.001] ) and COVID-19 EWS (training dataset 0.956 [95%CI 0.934-0.978, P < 0.001] ; validate dataset 0.966 [95%CI 0.929-1, P< 0.001]) had good discrimination capacity. In addition, we also obtained the cut-off values of disease severity predictors, such as CT score, CD8 + T cell count, CD4 + T cell count, and so on. CONCLUSIONSThe new developed COVID-19 EWS was a considerable tool for early and relatively accurately warning of SARS-CoV-2 infected patients.

An updated revision of Oriental Dryinidae is presented. Seven subfamilies, 20 genera and 368 species are treated. Eight new species are described: Aphelopus zonalis Xu, Olmi & He, sp. nov. (China, Hainan); Anteon zoilum Xu, Olmi & He, sp. nov. (China, Yunnan), Anteon zonarium Xu, Olmi & He, sp. nov. (China, Yunnan), Anteon zopyrum Xu, Olmi & He, sp. nov. (China, Xizang), Anteon zoroastrum Xu, Olmi & He, sp. nov. (Malaysia, Malaya), Esagonatopus sinensis Xu, Olmi & He, sp. nov. (China, Yunnan), Gonatopus yunnanensis Xu, Olmi & He, sp. nov. (China, Yunnan); Ponomarenkoa ellenbergeri Olmi, Xu & He, sp. nov. (Myanmar amber). Descriptions, geographic distribution, known hosts, natural en-emies and type material of each species are presented, together with illustrations of the main morphological characters and keys to the subfamilies, genera and species. Complete lists of references concerning the Oriental Dryinidae and their hosts are given. New synonymies are proposed for Aphelopus albiclypeus Xu, He & Olmi, 1999 (=A. exnotaulices He & Xu, 2002, syn. nov.), A. orientalis Olmi, 1984 (=A. albopictoides Xu & He, 1999, syn. nov.), A. taiwanensis Olmi, 1991 (=A. compresssus Xu & Yao, 1997, syn. nov.), A. niger Xu & He, 1999 (=A. nigricornis Xu, He & Olmi, 1999, syn. nov.), A. penanganus Olmi, 1984 (=A.olmii He & Xu, 2002, syn. nov.), Anteon cacumen Xu & He, 1997 (=A. longwangshanense Xu & He, 1997, syn. nov.), A. hilare Olmi, 1984 (=A. corax Olmi, 1984, syn. nov., =A. javanum Olmi, 1984, syn. nov., =A. serratum Xu & He, 1999, syn. nov.), A. lankanum Olmi, 1984 (=A. planum Xu & He, 1999, syn. nov.), A. munitum Olmi, 1984 (=A. bauense Olmi, 1984, syn. nov.), A. parapriscum Olmi, 1991 (=A. alpinum He & Xu, 2002, syn. nov.), A. peterseni Olmi, 1984 (=A. scrupulosum He & Xu, 2002, syn. nov.), A. yuani Xu, He & Olmi, 1998 (=A. yuae He & Xu, 2002, syn. nov.), Lonchodryinus bimaculatus Xu & He, 1994 (=L. niger He & Xu, 2002, syn. nov.), L. ruficornis (Dalman, 1818) (=L. melaphelus Xu & He, 1994, syn. nov.), Dryinus indicus (Kieffer, 1914) (=Chlorodryinus koreanus Móczár, 1983, syn. nov., =Dryinus masneri Olmi, 2009, syn. nov.), D. stantoni Ashmead, 1904 (=D. undatomarginis Xu & He, 1998, syn. nov., =D. wuyishanensis He & Xu, 2002, syn. nov.), Adryinus jini Xu & Yang, 1995 (=A. platycornis Xu & He, 1995, syn. nov.), Gonatopus nigricans (R. Perkins, 1905 (=G. fulgori Nakagawa, 1906, syn. nov., =G. insulanus He & Xu, 1998, syn. nov., Pseudogonatopus sogatea Rohwer, 1920, syn. nov.; P. pusanus Olmi, 1984, syn. nov.), G. nudus (R. Perkins, 1912) (=G. yangi He & Xu, 1998, syn. nov.), G. pedestris Dalman, 1818 (=Epigonatopus sakaii Esaki & Hashimoto, 1933, syn. nov.), G. rufoniger Olmi, 1993 (=Neodryinus hishimonovorus Xu & He, 1997, syn. nov.), G. schen-klingi Strand, 1913 (=G. euscelidivorus Xu & He, 1999, syn. nov.). New combinations are proposed for Deinodryinus con-strictus (Olmi, 1998), comb. nov. (from Anteon), Dryinus asiaticus (Olmi, 1984), comb. nov. (from Alphadryinus), D. barbarus (Olmi, 1984), comb. nov. (from Mesodryinus),...

Few complete mitochondrial genomes representing limited families in the order Hymenoptera have been sequenced. Here, we sequenced the complete mitochondrial genome of Diadegma semiclausum (Hymenoptera: Ichneumonidae). This genome is 18 728 bp long, the second largest hexapod mitochondrial genome sequenced in its entirety and that with the highest A+T content at 87.4%. Four tRNAs are rearranged compared with the ancestral arrangement. Gene rearrangement mechanisms are different among all three rearranged regions. Six tRNAs have a large variable loop, which is not found in other metazoan mitochondrial genomes. trnS(AGY) uses the abnormal anticodon TCT but trnK uses the normal CTT. The A+T-rich region is very long (2161 bp). An extremely A+T-rich (99.1%) 1515 bp tandem repeat region with three types of repeat elements is located between cox1 and cox2, and the most likely ancestral element originated from the 3' end of cox1. Independent tandem duplications followed by mutation-insertion-deletion is the best model to explain the formation of this region. These results indicate that independent evolutionary events occurred extensively, such as gene rearrangement events, gene rearrangement mechanisms, derivation of tRNA variable loops, and tandem repeat region evolutionary processes, all of which likely contribute to the diversified features of hymenopteran mitochondrial genomes.

An investigation of insect parasitoids of the diamondback moth, Plutella xylostella (Linnaeus), in brassica vegetable crops in the suburbs of Hangzhou was conducted during five periods from 1989 to 1997. Eight species of primary parasitoids were recorded: Trichogramma chilonis Ishii, Cotesia plutellae Kurdjumov, Microplitis sp., Oomyzus sokolowskii Kurdjumov, Diadromus collaris (Gravenhorst), Itoplectis naranyae (Ashmead), Exochus sp. and Brachymeria excarinata Gahan. Seven species of hyperparasitoids were also collected. Rates of parasitism of eggs of P. xylostella were usually very low. However, rates of parasitism of larvae and pupae were substantial and showed two peaks each year, around June-July and September-November respectively. Rates of parasitism during peaks were usually 10-60% and reached over 80% on a few occasions. Cotesia plutellae, O. sokolowskii and D. collaris were the major larval, larval-pupal and pupal parasitoids respectively. In the field, C. plutellae was active throughout the year. Oomyzus sokolowskii was active from May to October, entered a quiescent pupal stage in October-November to overwinter and did not emerge until next April-May. Diadromus collaris was recorded from April to July and October. Rates of parasitism of P. xylostella in radish and mustard fields were usually higher than those in cabbage and Chinese cabbage fields in the same locality. Negative correlations of parasitism rates between C. plutellae and O. sokolowskii indicate a competitive relationship for host larvae between these two larval parasitoids.

The relations among infant anger reactivity, approach behavior, and frontal EEG asymmetry, and their relations to inhibitory control and behavior problems in early childhood were examined within the context of a longitudinal study of temperament. Two hundred and nine infants’ anger expressions to arm restraint were observed at 4 months of age. Infants’ approach behaviors during play with an unpredictable toy and baseline frontal electroencephalogram (EEG) asymmetry were assessed at 9 months of age. Inhibitory control during a Go/No-Go task and parent-report of behavior problems were evaluated at 4 years of age. High anger-prone infants with left, but not right, frontal EEG asymmetry showed significantly more approach behaviors and less inhibitory control relative to less anger-prone infants. Although a link between anger proneness in infancy and behavior problems in early childhood was not found, a combination of low approach behaviors and poor inhibitory control was predictive of internalizing behaviors.

These findings indicate associations between threat bias and pediatric anxiety symptoms, and suggest that vigilance to external threats manifests more prominently in symptoms of social anxiety and school phobia, regardless of age and gender. These findings point to the role of attention bias to threat in anxiety, with implications for translational clinical research. The significance of applying standardized methods in multi-site collaborations for overcoming challenges inherent to clinical research is discussed.

Social working memory (WM) has distinct neural substrates from canonical cognitive WM (e.g., color). However, no study, to the best of our knowledge, has yet explored how social WM develops. The current study explored the development of social WM capacity and its relation to theory of mind (ToM). Experiment 1 had sixty-four 3- to 6-year-olds memorize 1-5 biological motion stimuli, the processing of which is considered a hallmark of social cognition. The social WM capacity steadily increased between 3- and 6-year-olds, with the increase between 4 and 5 years being sharp. Furthermore, social WM capacity positively predicted preschoolers' ToM scores, while nonsocial WM capacity did not; this positive correlation was particularly strong among 4-year-olds (Experiment 2, N = 144).

A checklist of all confirmed species of the family Scoliidae (Hymenoptera) from China is made based on the Chinese specimens in the Naturalis Biodiversity Center (RMNH, Leiden) and on additional specimens from the Chinese Academy of Insect Science (IOZ, Beijing), the Zhejiang University (ZJUH, Hangzhou), and the Sun Yat-sen University (SYSUBM, Guangzhou). The Scoliid species from China belong to one subfamily, two tribes, 11 genera and 52 species. Two species are deleted from the fauna of China: Campsomeriella ilanensis (Tsuneki, 1972) and Scolia (Discolia) quadripustulata Fabricius, 1782. One subspecies, i.e., Carinoscolia vittifrons nipponensis Uchida, 1933, status nov., is elevated to species rank. Scolia (Discolia) formosicola Betrem, 1928, status nov. and S. (D.) inouyei Okamoto, 1924 are re-instated valid species.