Capillaria hepatica

Ewing, G. M.; Tilden, I. L.

doi:10.1016/s0022-3476(56)80261-8

Cited by 18 publications

(1 citation statement)

References 2 publications

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“…This higher incidence in children may be due to their more frequent soil-hand-mouth contact [ 12 ]. Children or adults with the habit of eating soil (geophagia or pica) are especially at risk of infection [ 13 ]. The habit of geophagia has been observed in horses and is considered to indicate nutritional deficiency or boredom [ 14 ].…”

Section: Discussionmentioning

confidence: 99%

Capillaria hepatica (Calodium hepaticum) infection in a horse: a case report

et al. 2017

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Background Capillaria hepatica is a zoonotic parasite in humans and animals and has a worldwide distribution. However, infections in mammals apart from rodents, which are natural hosts of the parasite, have rarely been reported. This report describes the first known case of C. hepatica infection in a horse in Japan.Case presentationA 3-year-old filly without clinical signs was presented at a slaughterhouse in Japan. Gross examination revealed white to tan nodules 0.5 to 1.5 cm in diameter in the parenchyma of the liver. Histologically, the nodules had mature fibrous capsules and consisted of multifocal to coalescing granulomatous inflammations with numerous nematode eggs. The eggs were barrel shaped with an opercular plug on each end and double-layered shells; these findings are consistent with the features of C. hepatica eggs.ConclusionsTo our knowledge, this is the first case of C. hepatica infection in a horse in Japan. The pathological findings confirmed the presence of this pathogen in this part of the world, and they highlight the importance of this nematode in the differential diagnosis of hepatic granulomatous lesions in horses.

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Section: Discussionmentioning

confidence: 99%

Capillaria hepatica (Calodium hepaticum) infection in a horse: a case report

et al. 2017

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Hepatic Capillariasis

and¹,

Singleton²

2001

Parasitic Diseases of Wild Mammals

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Drug treatment of experimentalCapillaria hepatica infection in mice

Cheetham

Markus

1991

Parasitol Res

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This report presents the results obtained using 14 anthelmintic compounds that were tested in experimental white mice of the Swiss-Webster strain for their action against Capilaria hepatica. Four of the drugs effectively prevented deposition of C. hepatica ova in mouse liver. The doses at which these four drugs prevented greater than 99% of egg deposition were: albendazole, 30 mg/kg; febantel, 30 mg/kg; mebendazole, 3.13 mg/kg; and oxfendazole, 12.5 mg/kg. Of these, mebendazole is the only agent for which the application of five daily doses of 3.13 mg/kg lay within the dose range recommended for man.

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Capillaria hepatica

Cited by 18 publications

References 2 publications

Capillaria hepatica (Calodium hepaticum) infection in a horse: a case report

Capillaria hepatica (Calodium hepaticum) infection in a horse: a case report

Hepatic Capillariasis

Drug treatment of experimentalCapillaria hepatica infection in mice

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