Cancer Therapy-Related Cardiovascular Complications in Clinical Practice: Current Perspectives

Bohdan, Michał; Kowalczys, Anna; Mickiewicz, Agnieszka; Gruchała, Marcin; Lewicka, Ewa

doi:10.3390/jcm10081647

Cited by 15 publications

(11 citation statements)

References 113 publications

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“…По некоторым данным распространенность преходящих изменений на ЭКГ по типу ишемических достигает 68%, а в сочетании с повышением маркеров повреждения миокарда -43%. Летальность от кардиальных осложнений 5-ФУ составляет от 2,2 до 13% [138,141,135,139,136].…”

Section: патофизиология и клинические проявления ибс связанной с прот...unclassified

“…До начала терапии с потенциальной сосудистой токсичностью следует определить риск развития ИБС. К факторам риска ишемических осложнений относятся [137,134,139] Низкий риск -отсутствие ФР или наличие одного среднего ФР -1 балл (Low risk = no risk factor OR one medium1 risk factor); Средний риск -наличие средних ФР в сумме 2-4 балла (Medium risk = medium risk factors with a total of 2-4 points);…”

Section: диагностика ибс ассоциированной с противоопухолевой терапией...unclassified

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Eurasian clinical guidelines for cardiovascular complications of cancer treatments: diagnosis, prevention and treatment (2022)

Чазова

Агеев²,

Аксенова

et al. 2022

Evrazijskij kardiologičeskij žurnal

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Disclaimer. The EAC Guidelines represent the views of the EAC, and were produced after careful consideration of the scientific and medical knowledge, and the evidence available at the time of their publication. The EAC is not responsible in the event of any contradiction, discrepancy, and/or ambiguity between the EAC Guidelines and any other official recommendations or guidelines issued by the relevant public health authorities, in particular in relation to good use of healthcare or therapeutic strategies. Health professionals are encouraged to take the EAC Guidelines fully into account when exercising their clinical judgment, as well as in the determination and the implementation of preventive, diagnostic, or therapeutic medical strategies; however, the EAC Guidelines do not override, in any way whatsoever, the individual responsibility of health professionals to make appropriate and accurate decisions in consideration of each patient’s health condition and in consultation with that patient and, where appropriate and/or necessary, the patient’s caregiver. Nor do the EAC Guidelines exempt health professionals from taking into full and careful consideration the relevant official updated recommendations or guidelines issued by the competent public health authorities, in order to manage each patient’s case in light of the scientifically accepted data pursuant to their respective ethical and professional obligations. It is also the health professional’s responsibility to verify the applicable rules and regulations relating to drugs and medical devices at the time of prescription.

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Section: патофизиология и клинические проявления ибс связанной с прот...unclassified

Section: диагностика ибс ассоциированной с противоопухолевой терапией...unclassified

Eurasian clinical guidelines for cardiovascular complications of cancer treatments: diagnosis, prevention and treatment (2022)

Чазова

Агеев²,

Аксенова

et al. 2022

Evrazijskij kardiologičeskij žurnal

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“…The primary phenolic compounds in the three plant extracts employed to study liver detoxification treatment dandelion-leaf and root extracts, as well as a commercial root powder-were identified by HPLC analysis 9 . Oil Red O staining and triglyceride levels study both revealed lower lipid and triglyceride buildup.…”

Section: Herbal Detox Agents For Livermentioning

confidence: 99%

Herbodetox agents

Yadav

Monika

Rani

2022

ijhs

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From the skin to the liver, the human body has a built-in detoxification mechanism that keeps it running properly on a daily basis. The natural system has been undermined by our contemporary way of life, which includes increased levels of stress, pollution, and poor eating habits. The identification of naturally occurring herbs that may aid in the cleaning of the urinary system and/or other organs is urgently needed. These plants can be found in abundance in the wild. The actions of herbal agents and pollutants increase the body's vigour while also detoxifying the critical organs. The capacity of nature's detox herbs to cleanse the kidney, liver, intestines, skin, and blood of toxins has been revived in this study that aids the lungs, kidneys, digestive system, and skin.

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“…Increased radiation-related cardiotoxicity has been observed in some patients with solid tumors during long-term follow-up, with an incubation period of more than 10 years ( 3 , 4 ). This increased risk of CVD begins within the first 5 years after radiotherapy and increases over time, lasting more than 20 years ( 5 , 6 ).…”

Section: Introductionmentioning

confidence: 99%

Association between radiotherapy and risk of death from cardiovascular diseases in lung and bronchus cancer

Zhong

Wang

Gao

et al. 2023

Front. Cardiovasc. Med.

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BackgroundRadiotherapy plays an important role in the treatment of lung cancer. However, radiation-related deaths from cardiovascular disease (CVD) are a concern in these patients, and few studies have examined CVD-related death associated with lung cancer. We aimed to evaluate the risk of CVD-related death after radiotherapy in patients with lung and bronchus cancer.MethodsData were extracted from the surveillance, epidemiology, and end results database. Propensity score matching (PSM) was applied to reduce possible bias between patients who received radiotherapy and those who did not. The Kaplan–Meier method was used to estimate cardiovascular-specific survival (CVSS), and the log-rank test was used to compare CVSS between the radiotherapy and no radiotherapy groups. Cox proportional hazards regression analysis was performed to estimate the hazard ratio (HR) of CVD-related death.ResultsA total of 225,570 patients with lung and bronchus cancer were included, and 201,282 patients remained after PSM. Radiotherapy was identified as an independent risk factor for CVSS among patients with lung and bronchus cancer before PSM (HR: 1.18, P < 0.001) and after PSM (HR: 1.18, P < 0.001). Patients treated with radiotherapy had a significantly worse CVSS than those who did not receive radiotherapy before PSM (25-year CVSS: 49.9 vs. 56.4%, P = 0.002) and after PSM (25-year CVSS: 48.4 vs. 56.7%, P < 0.001). Radiotherapy was associated with more deaths from heart disease before PSM (81.9 vs. 77.2%, P < 0.001) and after PSM (83.0 vs. 78.7%, P < 0.001).ConclusionRadiotherapy is associated with an increased risk of CVD-related death, especially death from heart disease, in patients with lung and bronchus cancer. More efforts are needed to monitor cardiovascular health after radiotherapy.

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Cancer Therapy-Related Cardiovascular Complications in Clinical Practice: Current Perspectives

Cited by 15 publications

References 113 publications

Eurasian clinical guidelines for cardiovascular complications of cancer treatments: diagnosis, prevention and treatment (2022)

Eurasian clinical guidelines for cardiovascular complications of cancer treatments: diagnosis, prevention and treatment (2022)

Herbodetox agents

Association between radiotherapy and risk of death from cardiovascular diseases in lung and bronchus cancer

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