Camel colostrum: Nutritional composition and improvement of the antimicrobial activity after enzymatic hydrolysis

Abstract

Camel colostrum collected within 24 h after parturition was analyzed for physicochemical and microbiological composition. The average contents of fats, dry matter, mineral matter and proteins were 1.71±0. 51, 199.55±16.93, 9.75±0.5 and 143.42±36.42 gL -1 , respectively. Microbiological analysis of colostrum samples showed richness in yeasts and Lactic acid bacteria and absence of coliforms. The good microbial quality of camel colostrum is due to a number of antimicrobial molecules such as immunoglobulins and lactoferrin. The antimicrobial activity was evaluated against the pathogens Bacillus cereus, Staphylococcus aureus, Enterococcus faecium and Pseudomonas aeruginosa. At concentration of 20 g L -1 , colostrum caused an important inhibition of growth of all tested bacteria. It therefore seemed interesting to assess whether the compounds inhibit the growth of tested strains present in camel colostrum are resisting to the action of digestive enzymes. An in vitro hydrolysis by pepsin and pancreatin was then conducted. Hydrolyzed camel colostrum was still active against all pathogenic strains with inhibition rate ranging from 15.8% to 24.18%. This finding highlights the presence of antimicrobial fragments/peptides released during proteolytic hydrolysis that may contribute to the antimicrobial activity in camel colostrum and play a significant role in the host defence system.

Antibacterial Activity of Trypsin-Hydrolyzed Camel and Cow Whey and Their Fractions

“…Camel milk displayed a higher antibacterial effect compared with that of CaWH-III and CoWH-III; however, the results did reach statistical significance. This result is similar to that of Jrad [29]. Many studies have shown that hydrolysates with high biological activity comprise low molecular weight peptides [30,31].…”

Histological evaluation of camel colostrum extracts effects as a new biological therapy on auricular cartilage defect healing.

“…Camel is the desert ship in our country; it is one among the animals mentioned in Quran as a miracle of the God (16). The nutrients, immunoglobulins and growth factors that present in the camel colostrum are very essential for regeneration of defect tissues, especially the bioactive factors (3). For all these reasons, we design this project to evaluate histologically the effect of camel colostrum extract as a biological treatment for healing of auricular cartilage defects.…”

“…Colostrum is differ from mature milk by its nutritional contain and immunological composition. In the matter of fact, camel colostrum contains more protein, nonprotein nitrogen, vitamins, minerals, and ash than milk (3). IgG1, IgG2, and IgG3 are the main sub-classes' immunoglobulins which are presented in camel colostrum (4).…”

Antioxidant capacity of egg, milk and soy protein hydrolysates and biopeptides produced by Bromelia pinguin and Bromelia karatas-derived proteases

“…BP interfere in the metabolic regulation and modulation, and they are used as potential nutraceutics and as ingredients of functional foods. Also, they present important properties such as antioxidants, chelators, anticoagulant, antimicrobial, hypocholesterolemic, growth stimulating of probiotic bacteria and antihypertensive (Sun et al, 2014;Zeineb et al, 2015;Przybylski et al, 2016;Sabbione et al, 2016;Marques et al, 2015;Titov et al, 2016;Lafarga et al, 2016).…”