Body Temperature Enhanced Adhesive, Antibacterial, and Recyclable Ionic Hydrogel for Epidermal Electrophysiological Monitoring (Adv. Healthcare Mater. 15/2022)

Abstract

Electrophysiological Monitoring A multifunctional ionic hydrogel based on dual physical cross‐linked networks helps build a highly compliant and gapless interface with the skin, as described by Tailang Yin, Zhou Li, and co‐workers in article number 2200653. When applied as the epidermal electrode, it shows good capability to record multifarious electrophysiological signals with high signal‐to‐noise ratio and ultra‐low detection limit.

Smart Skin‐Adhesive Patches: From Design to Biomedical Applications

“…For instance, Liu et al developed an ionic hydrogel using polyvinyl alcohol (PVA) and branched polyethyleneimine (b‐PEI) composited with calcium chloride (CaCl 2 ) to formulate skin‐adhesive epidermal electrodes for real‐time health monitoring. [ 25 ] This hydrogel exhibited body temperature‐enhanced superior stretchability of 1291% with skin‐matched Young's modulus ≈10 kPa with an adhesive energy of ≈60 J m −2 , a stable ionic conductivity of 3.09 S m −1 , and outstanding antibacterial ability. The hydrogel crosslinking strategy was achieved by which hydroxyl groups (OH) of PVA formed hydrogen bonds (H‐bond) with amino groups (NH 2 ) of b‐PEI and CaCl 2 helped construct the coordination between OH/NH 2 and Ca 2+ within the polymer chains to well support adhesion to the skin.…”

Recent advances in adhesive materials used in the biomedical field: adhesive properties, mechanism, and applications

“…92,93 However, the defects of chemical synthetic adhesives often result in the poor elasticity of the adhesive sites, rejection of living tissues, and potential chemical toxicity, which are not conducive to their application in the biomedical field. 32,94 Therefore, after modifying some of their functional sites using chemical or bioengineering methods, an increasing number of composite adhesive materials have been prepared, including composites formed between viscous biomolecules, composites between biomolecules, and chemical modification. 95 There are many methods used to prepare composite adhesive materials, which can be roughly divided into physical mixing, modular gene, and chemical grafting methods.…”

Skin-like hydrogels: design strategy and mechanism, properties, and sensing applications

“…Temperature perception is the basic function of human skin, which can sense high and low temperatures. 178 The skin-like hydrogel with temperature sensing characteristics has the same ability as skin. 179 Skin-like hydrogels can feel temperature changes over a wide range of areas just like skin, and they can quantitatively analyze temperature to show real-time data.…”