Biosynthesis and characterization of copper oxide nanoparticles from indigenous fungi and its effect of photothermolysis on human lung carcinoma

Saravanakumar, Kandasamy; Shanmugam, Sabarathinam; Varukattu, Nipun Babu; MubarakAli, Davoodbasha; Kathiresan, K.; Wang, Myeong‐Hyeon

doi:10.1016/j.jphotobiol.2018.11.017

Cited by 139 publications

(29 citation statements)

References 44 publications

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“…Environmental pollution and cigarette smoking habits have significantly increased the incidence of lung and cardiovascular diseases 24,25 . Chemotherapeutics, radiation, and surgical approaches for curing the diseases are expensive, often toxic to normal cells and also causing side effects 1,26 .…”

Section: Introductionmentioning

confidence: 99%

Unveiling the potentials of biocompatible silver nanoparticles on human lung carcinoma A549 cells and Helicobacter pylori

Saravanakumar

Chelliah

MubarakAli

et al. 2019

Sci Rep

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Silver nanoparticles (AgNPs) are gaining importance in health and environment. This study synthesized AgNPs using the bark extract of a plant, Toxicodendron vernicifluum (Tv) as confirmed by a absorption peak at 420 nm corresponding to the Plasmon resonance of AgNPs. The AgNPs were spherical, oval-shaped with size range of 2–40 nm as evident by field emission transmission electron microscopy (FE-TEM) and particle size analysis (PSA). The particles formed were crystalline by the presence of (111), (220) and (200) planes, as revealed by X ray diffraction (XRD) and energy dispersive spectroscopy (EDS). The presence of amine, amide, phenolic, and alcoholic aromatics derived from Tv extract was found to be capping and or reducing agents as evident by Fourier-transform infrared spectroscopy (FTIR) spectra. The Tv-AgNPs were observed to be biocompatible to chick embryonic and NIH3T3 cells at various concentrations. Interestingly, Tv-AgNPs at the concentration of 320 µg. mL −1 induced 82.5% of cell death in human lung cancer, A549 cells and further 95% of cell death with annexin V FITC/PI based apoptosis. The Tv-AgNPs selectively targeted and damaged the cancer cells through ROS generation. The Tv-AgNPs displayed minimal inhibitory concentration (MIC) of 8.12 µg.mL −1 and 18.14 µg.mL −1 against STEC and H. pylori respectively. This multi-potent property of Tv-AgNPs was due to shape and size specific property that facilitated easy penetration into the bacterial and cancer cells for targeted therapy.

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Section: Introductionmentioning

confidence: 99%

Unveiling the potentials of biocompatible silver nanoparticles on human lung carcinoma A549 cells and Helicobacter pylori

Saravanakumar

Chelliah

MubarakAli

et al. 2019

Sci Rep

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“…The high growth rate of the oxide monomers in polarity solvents often results in the formation of large sized oxide particle aggregates with irregular shapes For controlling the shape and monodispersity of the oxide particles, the addition of the capping molecules to the reaction mixture at high temperature and pressure is achieved The mechanisms controlling the reactions are not well understood [109,[204][205][206][207][208][209][210][211][212][213][214][215][216][217][218][219] The particle size can be modulated by tuning synthesis parameters (the medium pH, temperature, concentration, incubation time, reaction time), in turn, their morphology by changing the organism (bacteria, fungi, yeast) or plants extracts used as stabilizing or reducing agents…”

Section: Hydro/solvothermalmentioning

confidence: 99%

Controlling the morphology of metal–organic frameworks and porous carbon materials: metal oxides as primary architecture-directing agents

et al. 2020

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“…Fungal mediated, cell free extract of Trichoderma asperellum was used to synthesize 10-190 nm range of copper oxide nanoparticles where in amide and aromatic groups of secondary metabolite was found to be as encapsulating or reducing agent determined by IR spectroscopy. This nanoparticle was also studied in vitro photothermal induced therapy of human lung carcinoma-A549 cancer cells [46]. Agaricus bisporus (fungus) mediated green synthesis of copper NPs of size range 2-10 nm which showed antimicrobial, antioxidant and cytotoxic activity against SW 620 colon cancer cells (Table 1) [47].…”

Section: Bacterial and Fungal Mediated Synthesismentioning

confidence: 99%

Copper Nanoparticles: A Review on Synthesis, Characterization and Applications

Harishchandra¹,

Pappuswamy

Pu³

et al. 2020

Asian Pac J Cancer Biol

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An emerging field of science “Nanotechnology” which is involved in manipulation of atoms and molecules has shown great potential in all fields of sciences. Nanotechnology deals with nanoparticles ranging from size 1 to 100 nm in diameter, due to small size and high surface area eventually increases the state of activity. This review focuses on metal and metal oxide nanoparticles and mainly on green synthesis, characterization and application of copper nanoparticles. Green synthesis of copper and copper oxide (Cu and CuO) is economically beneficial and ecofriendly. Copper nanoparticles are used in diverse fields such as biomedicine, pharmaceuticals, bioremediation, molecular biology, bioengineering, genetic engineering, dye degradation, catalysis, cosmetics and textiles. Structural properties and biological effects of copper nanoparticles have promising effectivity in field of life sciences.

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Biosynthesis and characterization of copper oxide nanoparticles from indigenous fungi and its effect of photothermolysis on human lung carcinoma

Cited by 139 publications

References 44 publications

Unveiling the potentials of biocompatible silver nanoparticles on human lung carcinoma A549 cells and Helicobacter pylori

Unveiling the potentials of biocompatible silver nanoparticles on human lung carcinoma A549 cells and Helicobacter pylori

Controlling the morphology of metal–organic frameworks and porous carbon materials: metal oxides as primary architecture-directing agents

Copper Nanoparticles: A Review on Synthesis, Characterization and Applications

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