Biosensors for Food Toxin Detection: Carbon Nanotubes and Graphene

Malhotra, Bansi D.; Srivastava, Saurabh; Augustine, Shine

doi:10.1557/opl.2015.165

Cited by 18 publications

(8 citation statements)

References 43 publications

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“…In recent years combining nanotechnology with the various available bio sensing techniques is bringing to life the so-called “nano-biosensors” which demonstrate rapid responses combined with high sensitivities. [67,68•,69•]…”

Section: Introductionmentioning

confidence: 99%

Nanotechnology to the rescue: using nano-enabled approaches in microbiological food safety and quality

Eleftheriadou

Pyrgiotakis²,

Demokritou³

2017

Current Opinion in Biotechnology

137

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Food safety and quality assurance is entering a new era. Interventions along the food supply chain must become more efficient in safeguarding public health and the environment and must address numerous challenges and new consumption trends. Current methods of microbial control to assure the safety of food and minimize microbial spoilage have each shown inefficiencies. Nanotechnology is a rapidly expanding area in the agri/feed/food sector. Nano-enabled approaches such as antimicrobial food-contact surfaces/packaging, nano-enabled sensors for rapid pathogen/contaminant detection and nano-delivered biocidal methods, currently on the market or at a developmental stage, show great potential for the food industry. Concerns on potential risks to human health and the environment posed by use of engineered nanomaterials (ENMs) in food applications must, however, be adequately evaluated at the developmental stage to ensure consumer's acceptance.

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Section: Introductionmentioning

confidence: 99%

Nanotechnology to the rescue: using nano-enabled approaches in microbiological food safety and quality

Eleftheriadou

Pyrgiotakis²,

Demokritou³

2017

Current Opinion in Biotechnology

137

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“…As shown in Figure 5 above, dispense-printing and functionalization improved the sensitivity, since the inhibiting effect was higher than for the unfunctionalized electrode. SWCNTs helped to increase the surface area of the WE [1], which led to attachment of more specific antibodies, consequently improving the sensitivity of the electrode.…”

Section: Resultsmentioning

confidence: 99%

“…The growth of different fungal genii like Aspergillus , Fusarium , Penicillium , Claviceps , and Alternania under favorable conditions in a variety of food products and in animal feed leads to the synthesis of their secondary metabolites, called mycotoxins [1,2,3]. It is estimated that approximately 25% of crops worldwide are contaminated with mycotoxin [4,5].…”

Section: Introductionmentioning

confidence: 99%

“…The best known mycotoxins are aflatoxins, ochratoxins, fumonisins, patulin, and trichothecenes. These toxins can represent potential hazards to human beings [1], since they are carcinogenic, teratogenic, mutagenic, nephrotoxic, hepatotoxic, immunotoxic, and may also damage the nerve system [2]. In particular, aflatoxin M1 (AFM1), a metabolic product of aflatoxin B1 (AFB1), is present in milk and milk products [6] and is the most toxic compound in this group [7,8].…”

Section: Introductionmentioning

confidence: 99%

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Development of Flexible Dispense-Printed Electrochemical Immunosensor for Aflatoxin M1 Detection in Milk

Abera

Falco

Ibba

et al. 2019

Sensors

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Detection of mycotoxins, especially aflatoxin M1 (AFM1), in milk is crucial to be able to guarantee food quality and safety. In recent years, biosensors have been emerging as a fast, reliable and low-cost technique for the detection of this toxin. In this work, flexible biosensors were fabricated using dispense-printed electrodes, which were functionalized with single-walled carbon nanotubes (SWCNTs) and subsequently coated with specific antibodies to improve their sensitivity. Next, the immunosensor was tested for the detection of AFM1 in buffer solution and a spiked milk sample using a chronoamperometric technique. Results showed that the working range of the sensors was 0.01 µg/L at minimum and 1 µg/L at maximum in both buffer and spiked milk. The lower limit of detection of the SWCNT-functionalized sensor was 0.02 µg/L, which indicates an improved sensitivity compared to the sensors reported so far. The sensitivity and detection range were in accordance with the limitation values imposed by regulations on milk and its products. Therefore, considering the low fabrication cost, the ease of operation, and the rapid read-out, the use of this sensor could contribute to safeguarding consumers’ health.

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“…Malhotra et al have reviewed the applications of nanomaterials based biosensor for food toxin detection and also on carbon nanotubes-graphene based biosensor for food toxin detection exclusively utilizing carbon nanomaterials for the electrochemical biosensor for mycotoxins detection (Malhotra et al 2014(Malhotra et al , 2015. These involve overview about the utilization of graphene, fullerenes, carbon nanotubes and their derivatives for the fabrication of electrochemical biosensor for AFB 1 detection.…”

Section: Introductionmentioning

confidence: 99%

Recent advances in nanomaterials integrated immunosensors for food toxin detection

2021

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For the management and prevention of many chronic and acute diseases, the rapid quantification of toxicity in food and feed products have become a significant concern. Technology advancements in the area of biosensors, bioelectronics, miniaturization techniques, and microfluidics have shown a significant impact than conventional methods which have given a boost to improve the sensing performance towards food analyte detection. In this article, recent literature of Aflatoxin B 1 (AFB 1 ), worldwide permissible limits, major outbreaks and severe impact on healthy life have been discussed. An improvement achieved in detection range, limit of detection, shelf-life of the biosensor by integrated dimensional nanomaterials such as zero-dimension, one-dimension and two-dimension for AFB 1 detection using electrical and optical transduction mechanism has been summarized. A critical overview of the latest trends using paper-based and micro-spotted array integrated with the anisotropic shape of nanomaterials, portable microfluidic devices have also been described together with future perspectives for further advancements.

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Biosensors for Food Toxin Detection: Carbon Nanotubes and Graphene

Cited by 18 publications

References 43 publications

Nanotechnology to the rescue: using nano-enabled approaches in microbiological food safety and quality

Nanotechnology to the rescue: using nano-enabled approaches in microbiological food safety and quality

Development of Flexible Dispense-Printed Electrochemical Immunosensor for Aflatoxin M1 Detection in Milk

Recent advances in nanomaterials integrated immunosensors for food toxin detection

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