Recent advances in nanomaterials integrated immunosensors for food toxin detection

Abstract

For the management and prevention of many chronic and acute diseases, the rapid quantification of toxicity in food and feed products have become a significant concern. Technology advancements in the area of biosensors, bioelectronics, miniaturization techniques, and microfluidics have shown a significant impact than conventional methods which have given a boost to improve the sensing performance towards food analyte detection. In this article, recent literature of Aflatoxin B 1 (AFB 1 ), worldwide permissible limits, major outbreaks and severe impact on healthy life have been discussed. An improvement achieved in detection range, limit of detection, shelf-life of the biosensor by integrated dimensional nanomaterials such as zero-dimension, one-dimension and two-dimension for AFB 1 detection using electrical and optical transduction mechanism has been summarized. A critical overview of the latest trends using paper-based and micro-spotted array integrated with the anisotropic shape of nanomaterials, portable microfluidic devices have also been described together with future perspectives for further advancements.

Engineered Nanomaterials for Improving the Nutritional Quality of Agricultural Products: A Review

“…Nanotechnology limits the material size to the level of 1~100 nm, which makes it superior to other technologies. At present, it is used in many fields, such as medical treatment [ 4 ], construction [ 5 ], biomaterials [ 6 , 7 ], textile [ 8 ], environmental protection [ 9 ], food processing and packaging, agriculture, which brings new opportunities and challenges to traditional industry technology. Nanotechnology is placed with high hopes to achieve sustainable green development.…”

A Novel Preanalytical Strategy Enabling Application of a Colorimetric Nanoaptasensor for On-Site Detection of AFB1 in Cattle Feed

“…Enzyme-linked immunosorbent assay (ELISA) has been well-studied for AFB1 detection in feedstuffs [ 26 , 27 ] and commercial kits have recently proved to be competitive with HPLC [ 28 ]. Likewise, novel immunosensors are under active development to improve analytical variables and to enable the on-site application of the devices [ 29 , 30 , 31 , 32 , 33 ]. However, despite these signs of progress, several challenges remain to be addressed to avoid under or overestimation of AFB1 concentration in the samples, including factors such as the preanalytical procedures, the composition of the extraction solvent, co-extracted compounds (matrix interference), and cross-reactivity of antibodies with molecules similar to the target [ 34 ].…”

Toxicological studies in poultry consuming fumonisin from corn contaminated with Brazilian Amazonian flora

“…Climate variability and global warming strongly affect agricultural food production in particular regions as tropical and subtropic areas of the world. Brazil is one of the largest producers and exporters of poultry and livestock products globally, and the performance of this market may be affected by variations in the quality of soybean and corn crops, which are primary substrates used in animal feed (Bhardwaj et al, 2021). Increases in the quality and productivity of the corn crop due to geographical expansion and the diffusion of new technologies, combined with a good diet and inherent conditions linked to the species, enhances the development of the avian market (Venkataramana et al, 2014).…”

“…There are reports of corn crops produced at various times of the year with the increasing appearance of phytopathogenic microorganisms that provoke the production of mycotoxins (Shen et al, 2018;Bhardwaj et al, 2021). The primary toxigenic organisms belong to the genera Fusarium, Aspergillus, and Penicillium (Bhardwaj et al, 2021). Fusarium verticillioides produces fumonisin, a toxic secondary metabolite (Priyanka et al, 2015;Shen et al, 2018).…”