Biological Activities of Polyphenols from Grapes

Abstract

The dietary consumption of grape and its products is associated with a lower incidence of degenerative diseases such as cardiovascular disease and certain types of cancers. Most recent interest has focused on the bioactive phenolic compounds in grape. Anthocyanins, flavanols, flavonols and resveratrol are the most important grape polyphenols because they possess many biological activities, such as antioxidant, cardioprotective, anticancer, anti-inflammation, antiaging and antimicrobial properties. This review summarizes current knowledge on the bioactivities of grape phenolics. The extraction, isolation and identification methods of polyphenols from grape as well as their bioavailability and potential toxicity also are included.

Evaluation of the Antioxidant Potential and Antioxidant Enzymes of Some Yemeni Grape Cultivars

“…7,39 Catechin and gallic acid act as free radical scavengers, and epicatechin has also demonstrated antibacterial activity and protective effects against membrane oxidation. 8 Grape juices are rich in phenolic compounds and different studies have demonstrated that these substances possess biologi cal activity related to health benefits for the consumers. 9,10 The phenolic compounds in grape juices, mainly the flavonoids flavanols, flavonols and anthocyanins, are associated with improved health, along with other compounds which are not flavonoids, such as phenolic acids and the stilbene resveratrol.…”

“…9,10 The phenolic compounds in grape juices, mainly the flavonoids flavanols, flavonols and anthocyanins, are associated with improved health, along with other compounds which are not flavonoids, such as phenolic acids and the stilbene resveratrol. [11][12][13][14] The flavonols are represented mainly by kaempferol, quercetin and myricetin and simple orthomethylated derivatives such as isorhamnetin, which have received considerable interest due to their antioxidant properties. 15 Among the flavanols, (+)-catechin, (-)-epicatechin and procyanidins have gained attention due to their antioxidant, antimicrobial and bactericidal activity.…”

“…15 Among the flavanols, (+)-catechin, (-)-epicatechin and procyanidins have gained attention due to their antioxidant, antimicrobial and bactericidal activity. 14 The principal anthocyanins found in juices are malvidin, cyanidin, delphinidin, petunidin, peonidin and pelargonidin. The consumption of these anthocyanins is associated to biological activities, such as antioxidant capacity and prevention of cardiovascular diseases.…”

Establishing the Equipment-Methodical Support for Determining the Properties of Extracts of Grape Pomace Extracts Produced in the Subcreative Water Environment

“…Extraction of SCW provides more complete extraction, there is a selectivity of the process in relation to different target products and the ecological purity of the extract obtained [4][5][6]9].…”

Screening of Ethanolic Extracts of Medicinal Herbal Drugs Against Oral Microbes

“…9 It has a grater action towards free radical scavenging, on comparison to others such as vitamin C and E. 9 Flavanols, flavonols, stilbenes and phenolic acids are the other phenolic compounds present in grape seed extract. [10][11][12][13] These phenolics are mainly distributed in the skin, stem, leaf and seed of grape.…”