Bioactivity studies and chemical profile of the antidiabetic plant Genista tenera

In vitro studies to assess the antidiabetic, anti-cholinesterase and antioxidant potential of Spergularia rubra

“…This fact is corroborated by the works of Rauter et al (2009) and Aquino et al (2001) who reported DPPH scavenging by rich C-glycosyl flavones fractions of Genista tenera and Anthurium versicolor, respectively. Furthermore, the second major phenolic compound in S. rubra, 6,8-diC-glucosyl apigenin had already shown a strong anti-radical activity (Velozo et al, 2009).…”

“…In addition, some di-C-glycosyl-flavones were isolated from this species and their structures elucidated by spectroscopic means (Bouillant et al, 1979(Bouillant et al, , 1984 and more recently the identification of 36 C-glycosyl-flavones, including acylated derivatives, was reported by our group (Ferreres et al, 2011). This kind of compound shows a broad spectrum of activities, such as antibiotic, pancreatic lipase inhibitors (Lee et al, 2010), radical scavenging (Aquino et al, 2001;Lin, Chen, Lee, & Lin, 2002;Rauter et al, 2009), cholinesterase inhibition and anti-hyperglycaemic (Rauter et al, 2009).…”

Identification of phenolic constituents of Cytisus multiflorus

“…The assignment of these compounds to orientin (fraction 3) (Kazuno et al, 2005), luteolin-5-O-glucoside (fraction 6) and luteolin-7-O-glucoside (fraction 7) (Rauter et al, 2009), which was based on the HPLC-DAD and MS n data, will not be discussed in detail, as they were previously described to occur in Fabaceae.…”

Assessment of the Antidiabetic Potential of the Ethanolic Extract of Date Palm (Phoenix Dactylifera) Seed in Alloxan-Induced Diabetic Rats

“…There was a significant (P<0.05) increase in the values obtained for superoxide dismutase, GSH and catalase in the diabetic group treated with P. dactylifera seed extract as compared to the diabetic control group which suggests an in vivo antioxidant activity of P. dactylifera seed. This might be attributed to the presence of considerable amounts of active flavonoids, phenols, steroids, and saponins resident in the seed as those compounds may scavenge free radicals liberated by alloxan in diabetic rats [66,67]. Moreover, since the seed contains a high amount of fiber, fiber might also play a role in the enhanced in-vivo antioxidant effect observed because it includes various types of complex carbohydrates that can influence the absorption and metabolism of carbohydrate and fat, leading to a lowered glucose level and consequently; a reduced auto-oxidation of glucose that generates more free radicals and thereby conserving and enhancing the endogeneous antioxidant parameters [48].…”