2013
DOI: 10.1590/s1984-82502013000300003
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Best herbs for managing diabetes: a review of clinical studies

Abstract: Diabetes mellitus is a public health problem which leads to serious complications over time. Experimentally, many herbs have been recommended for treating diabetes. In most cases, however, the recommendations are based on animal studies and limited pieces of evidence exist about their clinical usefulness. This review focused on the herbs, the hypoglycemic actions of which have been supported by three or more clinical studies. The search was done in Google Scholar, Medline and Science Direct databases using the… Show more

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Cited by 94 publications
(62 citation statements)
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“…These include Allium sativa, Gymnema sylvestre, Ocimum sanctum, Pterocarpus marsupium, Trigonella foenum graecum and Tinospora cordifolia. Moreover, most of these plants were clinically tested; the results were recommendation that physicians can depend on herbs in alleviating diabetes and its complications (Ghorbani, 2013;Pandey et al, 2011). Therefore, these herbal plants could be an alternative therapy for diabetes and its complications (Khan et al, 2012).…”
Section: Introductionmentioning
confidence: 99%
“…These include Allium sativa, Gymnema sylvestre, Ocimum sanctum, Pterocarpus marsupium, Trigonella foenum graecum and Tinospora cordifolia. Moreover, most of these plants were clinically tested; the results were recommendation that physicians can depend on herbs in alleviating diabetes and its complications (Ghorbani, 2013;Pandey et al, 2011). Therefore, these herbal plants could be an alternative therapy for diabetes and its complications (Khan et al, 2012).…”
Section: Introductionmentioning
confidence: 99%
“…The beneficial effects of estradiol on glucose homeostasis and body weight were mimicked by T. foenum-graecum. Hypoglycemic effect of T. foenumgraecum has been demonstrated previously in several experimental and clinical studies (27). This effect may be achieved by inhibition of intestinal glucose absorption, enhancing insulin actions on tissues, and activation of hepatic enzymes (28,29).…”
Section: Discussionmentioning
confidence: 69%
“…[2] Pathophysiology of diabetic vascular disease referred mainly to an abnormality in endothelial and smooth muscle cells related directly with the low level of some biologically active substances such as nitric oxide under the effect of hyperglycemia. [3] Current drug treatment of diabetes besides insulin is oral hypoglycemic drugs including insulin sensitizers (biguanides, thiazolidinediones), insulin secretagogues (sulfonylureas, meglitinides), α-glucosidase inhibitors, incretin agonists, and dipeptidyl peptidase-4.…”
Section: Introductionmentioning
confidence: 99%
“…[4] Therefore, the search for new antidiabetic agent alternatives with more effectiveness and less side effects has been continued. [2,[9][10][11][12] It was reported that their effects were due to the existence of many phytochemicals including alkaloids, flavonoids, glycosides, glycolipids, polysaccharides, peptidoglycans, carbohydrates, amino acids, and saponins. [9] The present study was planned to overlook the effect of a medicinal plant rosemary (R. officinalis) on fasting blood glucose (FBG), hemoglobin A1c (HbA1c), and Vitamin B12 levels in healthy human compared to Type 2 diabetic patients incorporated to glucomid and/or metformin treatment.…”
Section: Introductionmentioning
confidence: 99%