Benign schwannoma of the left cervical phrenic nerve

Anatomical study of phrenic nerve using ultrasound

“…Knowledge of the nerve's exact location, which may demonstrate individual variation, may have useful clinical applications, including optimisation of surgical approaches [9], facilitation of the accurate injection of anaesthetics when a regional block is considered and accurate study of phrenic nerve tumours [10][11][12][13]. Phrenic nerve block can indeed be used for the 3 Fig.…”

Phrenic nerve schwannoma presenting as an asymptomatic neck mass

“…While we suspected a neurogenic tumor based on the cytopathology and imaging characteristics, the origin of the tumor was unclear. Benign neurogenic tumors are rare pathologies to begin with, and schwannomas of the phrenic nerve in the head and neck are even rarer 1–3 . In addition, the patient did not have any clinical symptoms associated with the mass with the exception of right neck and shoulder numbness following the second biopsy.…”

“…1 The incidence of schwannomas in the head and neck region is reported to be as high as 45%. 1 However, schwannomas of the phrenic nerve in the head and neck region are exceedingly rare. 2,3 To our knowledge, there have been 4 reports in the English literature of phrenic nerve schwannomas arising from the cervical region over the past 20 years.…”

“…2,3 To our knowledge, there have been 4 reports in the English literature of phrenic nerve schwannomas arising from the cervical region over the past 20 years. 1,2,4,5 Neurogenic tumors of the phrenic nerve tend to be asymptomatic and benign. 1,5 However, they have potential for malignant transformation.…”

Clinicopathologic analysis of 7 cases of oral schwannoma and review of the literature

“…Analysis of the 7 cases studied (Table 1) shows a wide range in patient age for oral schwannomas, which can affect from newborns [13] to the elderly [7,19] (mean age, 31.7 years). Although previous studies have reported a male predominance, a review of the cases published so far revealed a slightly higher frequency of schwannomas among females (53.6%).…”