2010
DOI: 10.1016/j.anndiagpath.2010.02.009
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Clinicopathologic analysis of 7 cases of oral schwannoma and review of the literature

Abstract: Schwannomas, also known as neurilemmomas, are uncommon neoplasms apparently derived from Schwann cells. The growth of these tumors causes displacement and compression of the nerve of origin. Schwannomas are usually solitary lesions but can be multiple when associated with neurofibromatosis. Anti-S100 protein is the most widely used antibody for the identification of this neoplasm. Surgical excision is the treatment of choice for schwannomas, with few and controversial reports of recurrence or malignant transfo… Show more

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Cited by 43 publications
(36 citation statements)
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“…Immunohistochemical analysis is essential for the diagnosis of schwannomas and a positive reaction to protein S100 is typical [8]. Pathologists classify schwannomas into 7 subtypes; classical, celluler, plexiform, cranial nerve, melanotic, degenerated, and granular cell schwannoma [9].…”
Section: Discussionmentioning
confidence: 99%
“…Immunohistochemical analysis is essential for the diagnosis of schwannomas and a positive reaction to protein S100 is typical [8]. Pathologists classify schwannomas into 7 subtypes; classical, celluler, plexiform, cranial nerve, melanotic, degenerated, and granular cell schwannoma [9].…”
Section: Discussionmentioning
confidence: 99%
“…the inferior alveolar nerve [3,12,21]. Two types of schwannomas have been identified: peripheral neurogenic tumors located in soft tissues and central ones (intra) situated inside the bone [21].…”
Section: Discussionmentioning
confidence: 99%
“…In 1908, José Verocay discovered Schwannoma. [6] Etiology is said to be unknown; however, it is assumed that the lesion arises from the propagation of Schwann cells at a point inside the perineurium, which causes compression and displacement of the surrounding normal nerve. [7] It is most often difficult to find out the nerve of origin.…”
Section: Discussionmentioning
confidence: 99%
“…[4] However, about 1-2% occurs intraorally with tongue being the most common site followed by the palate, floor of mouth, oral mucosa, and mandible. [5,6] Ancient Schwannoma is an uncommon Schwannoma variant which is a slow growing encapsulated painless benign neoplasm. [3] Case Report…”
Section: Introductionmentioning
confidence: 99%