Benign cephalic histiocytosis

Barsky, B. L.

doi:10.1001/archderm.120.5.650

Cited by 10 publications

(1 citation statement)

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“…Its clinical manifestations are small, red-to-yellow papules distributed mainly on the head, face, neck, and shoulders, although it may become generalized. Cases involving fused papules and formation of reticulated patterns have also been reported3,4. The case discussed in this report displayed clinical characteristics of BCH with papules and plaques on the right cheek.…”

Section: Discussionmentioning

confidence: 59%

A Case of Benign Cephalic Histiocytosis

et al. 2011

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Benign cephalic histiocytosis (BCH) is a rare non-Langerhans cell histiocytosis of unknown etiology. Clinically, lesions are characterized by small, red-to-yellow papules distributed mainly on the head, face, neck, and shoulders of infants and children. Histopathological specimens show massive histiocytic infiltration of the superficial dermis. Immunohistochemically, they are positive for CD68, but negative for CD1a and S-100. Two cases have been reported so far in the relevant work published in Korean literature. Herein, we report on an additional case of BCH.

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Section: Discussionmentioning

confidence: 59%

A Case of Benign Cephalic Histiocytosis

et al. 2011

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Benign Cephalic Histiocytosis with Diabetes Insipidus

Weston

Travers

Mierau

et al. 2000

Pediatric Dermatology

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Benign cephalic histiocytosis is a rare skin condition consisting of small tan papules on the face and upper trunk that is believed not to be associated with internal organ involvement. The infiltrating histiocytes are not Langerhans' cells (LCs). We report a 5-year-old girl who presented with diabetes insipidus 1 year after developing multiple small brown asymptomatic skin papules. Histologic examination revealed a non-LC histiocytic proliferation in the dermis without epidermal invasion. She had infiltration of the pituitary stalk on brain imaging. Diabetes insipidus has heretofore been associated with LC histiocytosis and xanthoma disseminatum but not benign cephalic histiocytosis.

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