Basaloid squamous cell carcinoma of the uterine cervix: a rare aggressive variant of cervical malignancy

Sharma, JC; Kochar, Sps; Arora, Devandra; Vasudeva, Shalini; Prasad, Urmila; Talukdar, Rupa; Sandhu, Namrita; Sinha, P. P.

doi:10.21276/apjhs.2015.2.1.22

Cited by 3 publications

(3 citation statements)

References 18 publications

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“…The finding of involvement of the uterine cervix is exceptionally rare. 5 Regardless of its location; it has a specific morphological picture. It includes nests or cords of small basaloid cells, hyperchromatic epithelial cells with high nucleocytoplasmic ratios, foci of comedonecrosis, a tendency to palisade at the periphery of the tumour islands, having prominent peripheral palisading of cells in the tumour cell nests, and absence of significant stromal reaction.…”

Section: Discussionmentioning

confidence: 99%

“…There are data in the literature of several cases at an age younger than the standard for this disease. 5,16 The youngest female patient with this disease found by us was 35-year-old. 16 In this case, the tumour had exceptionally rapid growth.…”

mentioning

confidence: 90%

“…4 It is thought that the tumour has a more aggressive course than the classical cervical squamous cell carcinoma (SCC), higher metastatic potential, and poorer prognosis. 5 We present a case of a young woman with an asymptomatic course of BSCC, diagnosed on a prophylactic examination, which underwent radical surgical treatment performed thereafter.…”

Section: 3mentioning

confidence: 99%

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Basaloid squamous cell carcinoma of uterine cervix in a young adult - A case report

Yordanov¹,

Slavchev²,

Nanev³

et al. 2019

amj

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Basaloid squamous cell carcinoma of the uterine cervix is an extremely rare and aggressive malignancy. It has poorer clinical outcomes than squamous cell carcinoma of the uterine cervix. The tumour has specific microscopic features, and usually affects patients in their late 60s and 70s. We present a very rare case of a 30-year-old woman, who was diagnosed on a prophylactic examination and was treated with radical hysterectomy and pelvic lymph node dissection. The follow-up of the patient is ongoing.

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Section: Discussionmentioning

confidence: 99%

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confidence: 90%

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Basaloid squamous cell carcinoma of uterine cervix in a young adult - A case report

Yordanov¹,

Slavchev²,

Nanev³

et al. 2019

amj

View full text Add to dashboard Cite

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Basaloid Squamous Cell Carcinoma Cervix: A Case Report

Dewan,

Shrivastav,

Shrivastav

et al. 2024

Indian J Gynecol Oncolog

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Non-Metastatic Basaloid Squamous Cell Carcinoma of the Uterine Cervix in a Woman with History of Subtotal Hysterectomy

et al. 2017

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Introduction: Basaloid squamous cell carcinoma (BSCC) of the cervix is an uncommon tumor in female genital tract. The aggressive clinical behavior makes this entity distinguished from other SCC subtypes. Case Presentation: We described a case of basaloid squamous cell carcinoma in uterine cervix in a 62-year old woman with previous subtotal hysterectomy. Clinical and radiologic examination suggested a 3 cm mass in cervical stump involving left parametrium. She underwent trachelectomy and lymph node dissection followed by adjuvant radiochemotherapy. The light microscopy and immunohistochemistry warranted the basaloid SCC diagnosis that was suspected in pre-operational biopsy. The small, round to ovalshaped cells with scant cytoplasm and hyperchromatic nuclei were positive for cytokeratin AE1/AE3 (CK AE1/AE3) and negative for p63, C-KIT, chromogranin and synaptophysin. Conclusions: Although this tumor has an aggressive behavior, this is not enough to substantiate that BSCC has a poorer medical outcome as compared to conventional SCC of the cervix.

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Basaloid squamous cell carcinoma of the uterine cervix: a rare aggressive variant of cervical malignancy

Cited by 3 publications

References 18 publications

Basaloid squamous cell carcinoma of uterine cervix in a young adult - A case report

Basaloid squamous cell carcinoma of uterine cervix in a young adult - A case report

Basaloid Squamous Cell Carcinoma Cervix: A Case Report

Non-Metastatic Basaloid Squamous Cell Carcinoma of the Uterine Cervix in a Woman with History of Subtotal Hysterectomy

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