2019
DOI: 10.1590/1678-7757-2018-0348 View full text |Buy / Rent full text
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Abstract: Association of the co-expression of SOX2 and Podoplanin in the progression of oral squamous cell carcinomas -an immunohistochemical study SOX2 is a transcription factor related to the maintenance of stem cells in a pluripotent state. Podoplanin is a type of transmembrane sialoglycoprotein, which plays an important role in tumor progression and metastasis. This study aims to determine association of SOX2 and podoplanin expression in the progression of oral squamous cell carcinomas and to elucidate the associati… Show more

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“…Nuclear and cytoplasmic localization of SOX2 was reported in buccal SCC 20 and ameloblastic carcinoma 21 . On the other hand, nuclear localization of SOX2 was reported in oral SCC 22 …”
Section: Discussionmentioning
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“…Nuclear and cytoplasmic localization of SOX2 was reported in buccal SCC 20 and ameloblastic carcinoma 21 . On the other hand, nuclear localization of SOX2 was reported in oral SCC 22 …”
Section: Discussionmentioning
“…Em relação ao grau de diferenciação do tumor, o estudo de Pradhan et al (2019) apontou associação da maior expressão a maior grau histopatológico. O estudo de Liu et al Variáveis como grau de diferenciação, tamanho e estágio clínico do tumor são importantes fatores ao analisar o prognóstico do paciente com CECP.…”
Section: Discussionunclassified
“…Also, expression of SOX2 was found in 63% of OC cases. 27 Analysis of PPN thus can be an aid to prognosis and treatment of OSCC.…”
Section: + =Upregulation -=Downregulationmentioning