Aspiration Biopsy of the Spleen in Patients with Sarcoidosis

Taavitsainen, M.; Koivuniemi, A; Helminen, Johanna; Bondestam, S.; Kivisaari, Leena; Pamilo, M.; Tierala, E.; Tiitinen, Hannu

doi:10.1177/028418518702800613

Cited by 38 publications

(19 citation statements)

References 3 publications

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“…Dysfunction of liver and spleen is uncommon, although evidence of liver and spleen involvement is frequently obtained at microscopic examination. Needle biopsy of the liver demonstrated granuloma in 24%-79%of patients (3,4) and similar studies in the spleen showed sarcoid lesions in 24%-59%of…”

Section: Discussionmentioning

confidence: 54%

Hepatic and Splenic Sarcoidosis Evaluated by Multiple Imaging Modalities.

et al. 1998

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Wepresent a case of hepatosplenic sarcoidosis. A 51-year-old Japanese male, who was diagnosed to have sarcoidosis 4 years previously, was presented to our hospital because of dry cough and anorexia with weight loss. He had tender hepatosplenomegaly. A dynamic abdominal computed tomography (CT) revealed multiple small low-density areas in both liver and spleen, as well as in magnetic resonance imaging (MRI). The laparoscopic photographs showed many small whitish nodules surfacing on the liver and several tumorous nodules on the spleen. Multiple imaging modalities including dynamic CT and MRI are valuable for detecting focal hepatic and splenic lesions of sarcoidosis. (Internal Medicine 37: 449-453, 1998)

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Section: Discussionmentioning

confidence: 54%

Hepatic and Splenic Sarcoidosis Evaluated by Multiple Imaging Modalities.

et al. 1998

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“…6 The spleen is more frequently involved than the liver in systemic sarcoidosis. Splenic involvement is conrmed in 24 to 59z of patients by biopsy 7,8 and in 38 to 77z of patients by autopsy, 9 and one previous study showed splenic lesions in 69z of patients with hepatic sarcoidosis. 10 Hepatosplenic sarcoidosis most commonly manifests as organomegaly.…”

Section: Hepatosplenic Sarcoidosismentioning

confidence: 90%

Hepatosplenic and Muscular Sarcoidosis: Characterization with MR Imaging

Sekine¹,

Amano²,

Hidaka³

et al. 2012

magn reson med sci

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Sarcoidosis is a multisystem disorder of unknown etiology that involves multiple organs. Computed tomography is theˆrst-line imaging modality for diagnosing sarcoidosis because of its capacity to detect hilar lymphadenopathy and pulmonary lesions. Magnetic resonance (MR) imaging provides good soft tissue contrast that is useful for detecting sarcoidosis in some body parts, including skeletal muscle. Signal intensity on pre-and postcontrast T 1 -and T 2 -weighted imaging may re‰ect disease activity and the pathological appearance of sarcoidosis. In this review, we demonstrate these conventional MR imaginĝ ndings of hepatosplenic and muscular sarcoidosis and describe the usefulness of diŠusion-weighted imaging for detecting sarcoidosis.

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“…8 The most recent literature on this procedure comes from Europe. 2,4,[9][10][11] Although there are limited North American reports from the 1950s on utilization of sFNA for hematologic diseases and storage disorders, 12,13 the procedure has not gained much popularity. This paper reviews our experience with sFNA and splenic core biopsy (sCB) in 49 patients.…”

Section: Or Diffuse Splenomegaly (4) the Cytologic Diagnosis Was Neomentioning

confidence: 99%