Applications of Nanomaterials in Cell Stem Therapies and the Onset of Nanomedicine

Iancu, Cornel; Ilie, Ioana; Georgescu, Carmen Emanuela; Ilie, Razvan; Biriş, Alexandru R.; Mocan, Teodora; Mocan, Lucian; Zaharie, Florin; Todea-Iancu, Dana; Şuşman, Sergiu; Ciucă, D Rus; Biris, Alexandru S.

doi:10.1080/02726350903328985

Cited by 13 publications

(15 citation statements)

References 60 publications

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“…These nanoparticles can potentially be engineered as drug-delivery tools. 8 During the last decade, advances in functionalization chemistry have been one of the driving forces in the development of new classes of novel nanomaterials for applications in biology and medicine. [9][10][11][12][13][14][15] Gold nanoparticles (GNPs) with their physiochemical malleability and large surface area can strongly absorb near-infrared (NIR) radiance in the visible region by inducing coherent collective oscillation of conduction band electrons in strong resonance with visible frequencies of light.…”

Section: Mocan Et Almentioning

confidence: 99%

Surface plasmon resonance-induced photoactivation of gold nanoparticles as bactericidal agents against methicillin-resistant Staphylococcus aureus

Mocan¹,

Ilie²,

Matea³

et al. 2014

IJN

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Systemic infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and other bacteria are responsible for millions of deaths worldwide, and much of this mortality is due to the rise of antibiotic-resistant organisms as a result of natural selection. Gold nanoparticles synthesized using the standard wet chemical procedure were photoexcited using an 808 nm 2 W laser diode and further administered to MRSA bacteria. Flow cytometry, transmission electron microscopy, contrast phase microscopy, and fluorescence microscopy combined with immunochemical staining were used to examine the interaction of the photoexcited gold nano-particles with MRSA bacteria. We show here that phonon–phonon interactions following laser photoexcitation of gold nanoparticles exhibit increased MRSA necrotic rates at low concentrations and short incubation times compared with MRSA treated with gold nanoparticles alone. These unique data may represent a step forward in the study of bactericidal effects of various nanomaterials, with applications in biology and medicine.

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Section: Mocan Et Almentioning

confidence: 99%

Surface plasmon resonance-induced photoactivation of gold nanoparticles as bactericidal agents against methicillin-resistant Staphylococcus aureus

Mocan¹,

Ilie²,

Matea³

et al. 2014

IJN

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“…In addition, carbon nanotubes (CNTs) possess strong optical absorption in the near infrared (NIR) region and convert the absorbed light into heat, which provides the opportunity to create a new generation of immunoconjugates for cancer photothermal therapy. Earlier studies have shown the promise of using CNTs for the photothermal treatment of cancer cells in vivo [8,9].…”

Section: Introductionmentioning

confidence: 99%

Photothermal effects of multi-walled carbon nanotubes on the viability of BT-474 cancer cells

Chou

Wang

Lee

et al. 2013

Materials Science and Engineering: C

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“…Phototherapy is an emerging technique as an alternative for treating malignant tissues, in which inorganic particles (such as carbon nanotube, gold nanoparticles, and fullerenes) are usually utilized to produce heat or reactive oxygen species sufficient to ablate malignant cells . This treatment is a feasible method to generate localized thermal/dynamic damage to malignant cells when surgical resection is not possible.…”

Section: Introductionmentioning

confidence: 99%

Poly(ethylene glycol)‐crosslinked fullerenes for high efficient phototherapy

Lee

Ahn

Youn

et al. 2012

Polymers for Advanced Techs

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Poly(ethylene glycol)‐crosslinked multimeric C60 was developed for use in photothermal/photodynamic therapy of malignant cells. We showed that: (i) the tumor surface temperature on KB tumor‐bearing nude mice treated with multimeric C60 reached about 44 °C; (ii) this hyperthermic condition and tremendous singlet oxygen generation from multimeric C60 resulted in significant tumor volume regression in KB tumor‐bearing nude mice; and (iii) multimeric C60 also efficiently inhibited arthritic progress in the arthritis‐induced DBA/1 J mice model. This multimeric C60 may be useful for photothermal/photodynamic cell ablation in various malignant cells. Copyright © 2012 John Wiley & Sons, Ltd.

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Applications of Nanomaterials in Cell Stem Therapies and the Onset of Nanomedicine

Cited by 13 publications

References 60 publications

Surface plasmon resonance-induced photoactivation of gold nanoparticles as bactericidal agents against methicillin-resistant Staphylococcus aureus

Surface plasmon resonance-induced photoactivation of gold nanoparticles as bactericidal agents against methicillin-resistant Staphylococcus aureus

Photothermal effects of multi-walled carbon nanotubes on the viability of BT-474 cancer cells

Poly(ethylene glycol)‐crosslinked fullerenes for high efficient phototherapy

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