Photothermal effects of multi-walled carbon nanotubes on the viability of BT-474 cancer cells

Chou, Hung-Tao; Wang, Tsung-Pao; Lee, Chi-Young; Tai, Nyan‐Hwa; Chang, Hwan‐You

doi:10.1016/j.msec.2012.11.035

Cited by 28 publications

(14 citation statements)

References 30 publications

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“…Amide bond formation on the surface of nanocarriers is achieved via a stable and simple chemical reactions. Minimal activity loss, high stability and dispersion of resulting complexes in an aqueous environment, prolonged biodistribution, and large accumulation in cancer cells, as well as enhanced therapeutic outcomes, can be obtained using modified targeted delivery systems [47,[64][65].…”

Section: Essential Bonding In Carrier-systemsmentioning

confidence: 99%

Nano-Mediated Photodynamic Therapy for Cancer: Enhancement of Cancer Specificity and Therapeutic Effects

Tynga

Abrahamse

2018

Preprint

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Deregulation of cell growth and development lead to cancer, a severe condition that claims millions of lives worldwide. Targeted or selective approaches used during cancer treatment determine the efficacy and outcome of the therapy. In order to enhance specificity and targeting and better treatment options for cancer, novel and alternative modalities are currently under development. Photodynamic therapy has the potential to eradicate cancer and combination therapy would yield even greater outcomes. Nanomedicine-aided cancer therapy shows enhanced specificity for cancer cells and minimal side-effects coupled with effective cancer destruction both in vitro and in vivo. Nanocarriers used in drug-delivery systems are well able to penetrate cancer stem cell niche, simultaneously killing cancer cells and eradicate drug-resistant cancer stem cells, yielding therapeutic efficiency up to 100 fold against drug-resistant cancer in comparison with free drugs. Safety precautions should be considered when using Nano-mediated therapy as the effects of extended exposure to biological environments are still to be determined.

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Section: Essential Bonding In Carrier-systemsmentioning

confidence: 99%

Nano-Mediated Photodynamic Therapy for Cancer: Enhancement of Cancer Specificity and Therapeutic Effects

Tynga

Abrahamse

2018

Preprint

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“…Briefly, iron oxide (Fe 3 O 4 ) nanoparticles were characterized using a simple precipitation reaction: NaOH (1.030 g) and KNO 3 (1.820 g) in deionised water (H 2 O, 180 mL) was refluxed under nitrogen (N 2 ) for 1 h. ) polymer in deionised water rendering Fe 3 0 4 -PEI. Gold seeds (2 nm) were attached to the PEI surface (Fe 3 O 4 -PEI-Au seed ) followed by reduction of HAuCl 4 forming a complete shell [26]. The HNPs were washed extensively with deionised water and stored at room temperature.…”

Section: Synthesis Of Hybrid Nanoparticlesmentioning

confidence: 99%

“…These include nanoparticles composed of iron oxide [1], gold [2], quantum dots [3], carbon nanotubes [4], silver nanoparticles [5] and many more. Hybrid nanoparticles (HNPs) composed of an iron oxide core surrounded by a gold shell have shown potential for image guided cancer therapy [6].…”

Section: Introductionmentioning

confidence: 99%

Heat Dissipation of Hybrid Iron Oxide-Gold Nanoparticles in an Agar Phantom

Curtis

Malekigorji

Holman

et al. 2015

J Nanomed Nanotechnol

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Hybrid iron oxide-gold nanoparticles (HNPs) have shown potential in cancer therapy as agents for tumour ablation and thermal switches for targeted drug release. Heat generation occurs by exploitation of the surface plasmon resonance of the gold coating, which usually occurs at the maximum UV absorption wavelength. However, lasers at such wavelength are often expensive and highly specialised. Here, we report the heating and monitoring of heat dissipation of HNPs suspended in agar phantoms using a relatively inexpensive Ng: YAG pulsed 1064 nm laser source. The particles experience heating of up to 40°C with a total area of heat dissipation up to 132.73 mm 2 from the 1 mm diameter irradiation point after 60 seconds. This work reports the potential and possible drawbacks of these particles for translation into cancer therapy based on our findings.

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“…Lastly, the photothermal conversion materials are placed in lesions to enhance the light absorption and heat conversion in the tumors. The rapid development of biotechnology and nanotechnology provides several kinds of photothermal conversion materials including metallic nanoparticles 21,22 , magnetic nanoparticles 23 , semiconductor quantum dots (CdSe, CdTe) 24,25 , carbon-based nanomaterials (graphene, carbon nanotubes) 26,27 , organic nanoparticles (dyes, polymer, biomacromolecule) 28–30 for PTT. Despite the effective conversion from light energy to heat, these photothermal conversion materials still exhibit some limitations such as weak biological compatibility and long-term toxicity in clinical applications 31 .…”

Section: Introductionmentioning

confidence: 99%

Dually functioned core-shell NaYF4:Er3+/Yb3+@NaYF4:Tm3+/Yb3+ nanoparticles as nano-calorifiers and nano-thermometers for advanced photothermal therapy

Zhang

Chen

et al. 2017

Sci Rep

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To realize photothermal therapy (PTT) of cancer/tumor both the photothermal conversion and temperature detection are required. Usually, the temperature detection in PTT needs complicated instruments, and the therapy process is out of temperature control in the present investigations. In this work, we attempt to develop a novel material for achieving both the photothermal conversion and temperature sensing and control at the same time. To this end, a core-shell structure with NaYF4:Er3+/Yb3+ core for temperature detection and NaYF4:Tm3+/Yb3+ shell for photothermal conversion was designed and prepared. The crystal structure and morphology of the samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Furthermore, the temperature sensing properties for the NaYF4:Er3+/Yb3+ and core-shell NaYF4:Er3+/Yb3+@NaYF4:Tm3+/Yb3+ nanoparticles were studied. It was found that the temperature sensing performance of the core-shell nanoparticles did not become worse due to coating of NaYF4:Tm3+/Yb3+ shell. The photothermal conversion behaviors were examined in cyclohexane solution based on the temperature response, the NaYF4:Er3+/Yb3+@NaYF4:Tm3+/Yb3+ core-shell nanoparticles exhibited more effective photothermal conversion than that of NaYF4:Er3+/Yb3+ nanoparticles, and a net temperature increment of about 7 °C was achieved by using the core-shell nanoparticles.

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Photothermal effects of multi-walled carbon nanotubes on the viability of BT-474 cancer cells

Cited by 28 publications

References 30 publications

Nano-Mediated Photodynamic Therapy for Cancer: Enhancement of Cancer Specificity and Therapeutic Effects

Nano-Mediated Photodynamic Therapy for Cancer: Enhancement of Cancer Specificity and Therapeutic Effects

Heat Dissipation of Hybrid Iron Oxide-Gold Nanoparticles in an Agar Phantom

Dually functioned core-shell NaYF4:Er3+/Yb3+@NaYF4:Tm3+/Yb3+ nanoparticles as nano-calorifiers and nano-thermometers for advanced photothermal therapy

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