Antioxidant and Antimicrobial Activities of Essential Oil and Extracts of Saurauia lantsangensis Hu Root

Abstract

Antioxidant and antimicrobial activities of the essential oil and n-hexane (HEE), chloroform (CHE), ethyl acetate (EAE), and methanol (MEE) extracts, respectively, from the root of Saurauia lantsangensis Hu were investigated. The GC-MS analysis revealed 39 compounds representing 96.41% of the oil containing T-muurolol (13.85%), acetophenone (7.46%), α-cadinol (6.26%), methyl palmitate (5.36%), n-hexadecanoic acid (4.31%), torreyol (3.69%), and isospathulenol (3.48%) as major components. Antioxidant activities determined by three various testing systems, i. e. DPPH radical scavenging, superoxide anion radical scavenging, and reducing power assay, increased in the order: HEE < CHE < oil < MEE < EAE. CHE, EAE, MEE and oil exhibited a promising antimicrobial effect determined as the diameter of zones of inhibition (13.3 -16.2, 16.5 -20.4, 13.5 -16.6, and 16.5 -22.7 mm), respectively, along with their respective MIC values (500 -1000, 125 -500, 250 -500, and 250 -500 μg/ml) against Gram-negative bacteria (Pseudomonas aeruginosa, Escherichia coli), Gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus), and a yeast (Hansenula anomala).

A Review on Genus Saurauia: Chemical Compounds and their Biological Activity

“…Major components of the oil were T-muurolol (13.85%), followed in the decreasing order by consecutively acetophenone (7.46%), α-cadinol (6.26%), methyl palmitate (5.36%), n-hexadecanoic acid (4.31%), torreyol (3.69%), and isospathulenol (3.48%). 37 Chemical constituents in Saurauia excelsa plant species have been reported by particular researchers. They examined that Saurauia excelsa species was originated from Venezuela and belonged to the family Accinidaceae.…”

“…At 100 μg/ml, the superoxide anion radical scavenging activities of the ethyl acetate extract, methanol extract, and BHT were (92.4±3.2), (83.6±2.8), and (76.7±3.3) %, respectively. 37 Parts of plants used and their bioactivity are presented in Table 2. Lovena et al .2018 reported that the antioxidant activity value of the water extract from Saurauia vulcani IC 50 values was 22,9182±1.32μg/ mL, whereas the IC 50 value of the produced-quercetin was 4.96±0.02 μg/ml.…”

“…negative bacteria (Pseudomonas aeruginosa, Escherichia coli), Grampositive bacteria (Bacillus subtilis, Staphylococcus aureus), and a yeast (Hansenula anomala). 37 Ahmed et al 2015 reported in vitro the role of antibacterial activity isolated from the leaves of Saurauia roxburghii (Table 4). The crude extracts and isolated pure compounds of the leaves posed the potential antibacterial activities which might provide support for some of their uses in ethnomedicine treatment.…”