“…Previous studies have focused on the isolation and characterization of secondary metabolites, whereas it has been demonstrated that some of the extracts or active principles obtained from Physalis species have a broad spectrum of biological activities, including antileukemic, antitumor, immunomodulator, cytotoxic, antimycobacterial, antimicrobial, molluscicidal, antihepatoma, and antinociceptive activities in recent studies (Chiang et al, 1992a(Chiang et al, , 1992bJanuário et al, 2002;Shim et al, 2002;Su et al, 2002;Dos Santos et al, 2003;Soares et al, 2003;Wu et al, 2004;Choudhary et al, 2005;Lee & Houghton, 2005;Silva et al, 2005;Bastos et al, 2006;Magalhaes et al, 2006;Damu et al, 2007;Castro et al, 2008). It has been previously reported that the crude extract (i.e.…”