2009
DOI: 10.3109/13880200903062606
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Antimicrobial activity of the extracts and physalin D fromPhysalis alkekengiand evaluation of antioxidant potential of physalin D

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Cited by 70 publications
(39 citation statements)
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References 39 publications
(55 reference statements)
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“…It was shown that the dichloromethane extract and physalin D had low activity against fungi, at MIC values ranging from 256 to 512 µg/ml. Additionally, the antioxidant activity of physalin D was evaluated by qualitative DPPH radical-scavenging and thiobarbituric acid-reactive substance (TBARS) assays, showing low antioxidant activity with an IC 50 value of ≥10 ± 2.1 μg/mL [79]. …”
Section: Resultsmentioning
confidence: 99%
“…It was shown that the dichloromethane extract and physalin D had low activity against fungi, at MIC values ranging from 256 to 512 µg/ml. Additionally, the antioxidant activity of physalin D was evaluated by qualitative DPPH radical-scavenging and thiobarbituric acid-reactive substance (TBARS) assays, showing low antioxidant activity with an IC 50 value of ≥10 ± 2.1 μg/mL [79]. …”
Section: Resultsmentioning
confidence: 99%
“…Physalin D yielded a quasimolecular ion with an m/z 544. 9 [M+H] + , while the IS molecule showed a quasi-molecular ion with m/z 286.7 [M+H] + and these ions were chosen as parent ions for fragmentation in the MRM mode. The product ions m/z 508.8 and m/z 152.8 were selected as the target ions of physalin D and IS, respectively.…”
Section: Optimization Of Ms Conditionsmentioning
confidence: 99%
“…Januário et al's research showed that physalin D plays a relevant role in the antimycobacterial activity [2]. Other studies showed that physalin D also has immune depression [6], cytotoxic [1,7,8] and antimicrobial [9] activities. All these activities suggested that physalin D may be a good lead compound for further new drug studies.…”
Section: Introductionmentioning
confidence: 99%
“…middle ear infection, sore throat, abscesses, and urinary problems (Helvaci et al, 2010). Research has found that PA contains physalins, flavonoids, alkaloids and megastigmane glycosides (Qiu et al, 2008).…”
Section: Introductionmentioning
confidence: 99%