Antimicrobial Drug Use in Cattle

Apley, Michael D.; Coetzee, Johann F.

doi:10.1002/9781118675014.ch29

Cited by 14 publications

(14 citation statements)

References 40 publications

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“…While it is clear that the use of antimicrobial agents has broad and significant benefits, the appropriate use of these agents, including their selection, administration, monitoring and assessment, is a highly skilled discipline that incorporates all of the experience and expertise of veterinarians. Valuable sources of information that veterinarians rely on include textbooks and chapters on infectious diseases of multiple livestock species (47,86,97,213,244), or specific species such as cattle (7,10,48,283), sheep and goats (3,175), pigs (33,80,177,298), and poultry (112,142,199,225).…”

Section: Global Sales Of Antimicrobial Products For Use In Livestockmentioning

confidence: 99%

Use of antimicrobial agents in livestock

Page¹,

Gautier²

2012

Rev. Sci. Tech. OIE

195

181

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Antimicrobial agents, especially antibacterial agents, are used throughout the world, across a diverse array of extensive and intensive livestock production systems, to protect the health and welfare of livestock and to improve their performance. While some agents that are used in livestock belong to classes that have no counterpart in human medicine, this is not the case for the most widely used agents: the tetracyclines, penicillins, macrolides and sulphonamides. Many bacterial diseases of livestock cause devastating losses of animal life and productivity. As a result, their keepers can lose their livelihoods and see a dramatic reduction in income, so there is often a great sense of urgency to treat affected animals early. However, there are a large number of bacterial pathogens that cause disease and it is frequently difficult to reach a conclusive diagnosis prior to instituting treatment. There are many ways in which existing uses of antimicrobial agents can be improved, amongst the most important are increased utilisation of veterinary professional services, the introduction of enhanced infection control measures, improved point-of-care diagnostic tests, and the application of physiologically based population pharmacokinetic-pharmacodynamic modelling.

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Section: Global Sales Of Antimicrobial Products For Use In Livestockmentioning

confidence: 99%

Use of antimicrobial agents in livestock

Page¹,

Gautier²

2012

Rev. Sci. Tech. OIE

195

181

View full text Add to dashboard Cite

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“…Mannheimia, Pasteurella, and Haemophilus are three major pathogens responsible for respiratory disease in cattle, and they constitute one of the biggest health challenges for dairy cattle (Barrett, 2000;Rerat et al, 2012). Tetracyclines, especially chlortetracycline and oxytetracycline, are commonly added to feed and water to treat cattle respiratory disease (Apley and Coetzee, 2006). Other approved antibiotics for bovine respiratory disease treatment include aminoglycosides, especially spectinomycin and neomycin, macrolides in the form of tilmicosin and erythromycin, tylosin, penicillins (amoxicillin and ampicillin), cephalosporin especially ceftiofur, and sulfonamides (sulfamethazine and sulfadimethoxine).…”

Section: Approved Antibiotics Against Livestock Diseasesmentioning

confidence: 99%

Animal Health: Global Antibiotic Issues

Peng

Biswas

2014

Encyclopedia of Agriculture and Food Systems

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“…The most widely used antibiotics for treatment of pneumonia in cattle are macrolides and quinolones. Beta lactams and florfenicol are also commonly used antibiotics for the treatment of pneumonia in ruminants (Apley & Coetzee 2013 ). Procaine penicillin, amoxicillin, ampicillin, oxytetracycline, erythromycin, tylosin, enrofloxacin and new molecules such as ceftiofur, tulathromycin and florfenicol are antibiotics widely used in the treatment of pneumonia in goats (Clothier et al 2012 ; Elitok et al 2015 ; Fleming 2009 ; Matthews 2009 ).…”

Section: Introductionmentioning

confidence: 99%

“…Procaine penicillin, amoxicillin, ampicillin, oxytetracycline, erythromycin, tylosin, enrofloxacin and new molecules such as ceftiofur, tulathromycin and florfenicol are antibiotics widely used in the treatment of pneumonia in goats (Clothier et al 2012 ; Elitok et al 2015 ; Fleming 2009 ; Matthews 2009 ). Quinolones are commonly used antibiotics in pneumonia owing to their broad spectrum and higher penetration rates into lung tissue (Apley & Coetzee 2013 ; DeDonder et al 2016 ). A quinolone antibiotic marbofloxacin (MR) has been demonstrated to be effective in the treatment of contagious caprine pleuropneumonia (Balikçi et al 2008 ).…”

Section: Introductionmentioning

confidence: 99%

Comparing clinical effects of marbofloxacin and gamithromycin in goat kids with pneumonia

Kaçar

Batmaz

Yılmaz

et al. 2018

J. S. Afr. Vet. Assoc.

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The aim of this study was to compare the clinical efficacy of a single-dose of gamithromycin (GM) or marbofloxacin (MR) in kids with naturally occurring pneumonia. Thirty-six kids, aged 2–2.5 months, with body weight ranging from 12 kg to 18 kg were presented with clinical signs of pneumonia. The most prominent clinical findings were an increase in the respiratory rate, crackling lung sounds on auscultation, coughing, nasal discharge and an increased rectal temperature. Mannheimia haemolytica and Mycoplasma spp. colonies were isolated from microbiological examination of six transtracheal washes and lung tissues of one necropsied kid. The severity of pneumonia was evaluated by using cumulative clinical score (CCS). The CCS of the 36 kids used in the study were four and above. Kids were randomly divided into two equal groups; the GM group received a single subcutaneous dose of GM at a dosage of 6 mg/kg and the MR group received MR intramuscularly at a dosage of 8 mg/kg as a single-dose. No side effects related to the drugs were detected in either group. All 36 kids were clinically examined 3 weeks after the initiation of the treatment. Clinical signs in both groups were almost completely absent at the end of the study. A single administration of GM or MR was successfully used in the treatment of kids with pneumonia.

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Antimicrobial Drug Use in Cattle

Cited by 14 publications

References 40 publications

Use of antimicrobial agents in livestock

Use of antimicrobial agents in livestock

Animal Health: Global Antibiotic Issues

Comparing clinical effects of marbofloxacin and gamithromycin in goat kids with pneumonia

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