Antimicrobial activity of four different dental gel formulas on cariogenic bacteria evaluated using the linear regression method

Bou‐Chacra, Nádia Araci; Gobi, Sandra Sayuri; Ohara, Mitsuko Taba; Pinto, Terezinha de Jesus Andreoli

doi:10.1590/s1516-93322005000300005

Cited by 15 publications

(13 citation statements)

References 15 publications

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“…Antimicrobial agents kill microorganisms by disrupting their cell wall and inhibiting their enzymatic activity. They also slow multiplication and prevent bacterial aggregation (Bou-Chacra et al 2005). Data from the present study support the assertion from several clinical studies that demonstrated the inhibitory effects of antimicrobial toothpastes on oral bacteria and gingiva (Fine et al 2006) All toothpastes in the study have shown antimicrobial effect (table 5).…”

Section: Antimicrobial Testsupporting

confidence: 88%

Formulation, physicochemical evaluation and antimicrobial activity of green toothpaste on streptococcus mutans

Ogboji

Chindo

Jauro

et al. 2018

IJAC

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Background: Toothpaste is a cosmetic product with increasing relevance and demand. However most commercial toothpaste consist of complex chemicals whose health safety remain unclear.Objectives: The present work involves the formulation, and comparative physicochemical evaluation and antimicrobial activity of green toothpaste and three commercial toothpastes (Close-Up, Oral-B and Dabur-Herbal)Methods: The green toothpaste were formulated using Tumeric (Curcuma longa), Aloe Vera (Aloe barbadensis miller), Guava (Psidium guajava), Mint (Mentha piperita), Neem (Azadirachta indica), and Lemon (Citrus lemon) as the active ingredients and comparatively evaluated for various properties like colour, taste, odor, texture, abrasivity, spreadability, cleansing ability, foaming ability, stability, homogeneity, moisture content, gritty matter and pH. The antimicrobial activity of the formula was comparatively tested on Streptococcus mutans (the major causative organism of dental caries).Results: Cold extracts of plant materials with ethanol showed a relative low (3.6% - 6.8%) percentage recovery of bioactive compounds. Physico-chemical tests revealed that the spreadability, pH, foam, gritty matter and homogeneity gave favourable results that compares well with commercial ones. The result of the antimicrobial test shows significant difference between the mean zones of inhibition of the various toothpastes.Conclusion: The results of the study agree with traditional application of the herbaceous plants and showed that the formulated toothpaste contains phytochemicals which possess antimicrobial properties and may be safer compared to toothpaste consisting of synthetic chemicals.

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Section: Antimicrobial Testsupporting

confidence: 88%

Formulation, physicochemical evaluation and antimicrobial activity of green toothpaste on streptococcus mutans

Ogboji

Chindo

Jauro

et al. 2018

IJAC

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“…They also prevent bacterial aggregation, slow multiplication and release endotoxins. 8 Data from the present study is in support of this assertion as all the investigated dental care products exhibited wide variations in their effectiveness against the three test microorganisms, a feature that may have been largely due to their antimicrobial active ingredients (Table 1). Among all the investigated toothpastes, Toothpaste 1 emerged as the most effective, based on the mean diameter of the zone of microbial inhibition produced by the toothpastes in agar well diffusion method, against E coli.…”

Section: Discussionsupporting

confidence: 76%

Antimicrobial Efficacy of Commercially Available Toothpastes – An In vitro Study

Roopavathi¹,

Gopal²,

Govindaraju³

et al. 2015

JYP

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Background: The use of antimicrobial chemotherapeutic agent has been proposed as a means of reducing the levels of oral bacteria. Many chemotherapeutic agents claim to have antimicrobial properties. Hence this in vitro study had been undertaken. Methods: This in vitro study comprised of seven toothpastes which have been tested for their antimicrobial activity against three oral pathogens namely, Streptococcus mutans, Escherichia coli and Candida albicans by well agar diffusion assay at the dilution of 1:1, 1:2, 1:4, 1:8 and 1:16. Results: Study results showed that toothpaste 'five' with sodium fluoride and sylodent as main ingredients showed maximum zone of inhibition against Streptococcus mutans where as against Candida albicans, toothpaste 'six' with xylitol and sodium fluoride as main ingredients showed maximum zone of inhibition. And against E. coli, toothpaste 'one' with Triclosan and Zinc sulphate as main ingredients showed maximum zone of inhibition among all toothpastes. It was observed that tooth paste 'six' with sodium fluoride and Neem, Meswak as main ingredient showed minimum zone of inhibition against Streptococcus mutans at 1:1 dilution among seven toothpastes used in the present study. Conclusion: In the present study, it has been demonstrated that triclosan containing toothpastes formulations are more effective in control of oral micro flora.

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“…Pan et al (19), Riep et al (22), and Pitten and Kramer (20) evaluated the rate of microbial death after contact with antiseptic mouthrinses and observed that products containing essential oils were more effective. BouChacra et al (6), who evaluated the antimicrobial activity of dental gel formulas on cariogenic bacteria using the linear regression method, noticed that formulas containing essential oils showed higher bactericidal activity . Meiller et al (15), who evaluated the antifungal efficacy of three formulas containing essential oils and one containing chlorhexidine, observed that all products presented activity against yeasts in the commercially available concentration and, the formulas containing essential oils showed better results.…”

Section: Resultsmentioning

confidence: 99%

Antimicrobial efficacy of Curcuma zedoaria extract as assessed by linear regression compared with commercial mouthrinses

Bugno¹,

Nicoletti²,

Almodóvar³

et al. 2007

Braz. J. Microbiol.

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The antimicrobial activity of Curcuma zedoaria (Christm) Roscoe extract against some oral microorganisms was compared with the antimicrobial activity of five commercial mouthrinses in order to evaluate the potential of the plant extract to be incorporated into formulas for improving or creating antiseptic activity. The in vitro antimicrobial efficacy of plant extracts and commercial products were evaluated against Streptococcus mutans, Enterococcus faecalis, Staphylococcus aureus and Candida albicans using a linear regression method to evaluate the microbial reduction obtained in function of the exposure time, considering as effectiveness a 99.999% reduction in count of standardized microbial populations within 60 seconds. The results showed that the antimicrobial efficacy of Curcuma zedoaria (Christm) Roscoe extract was similar to that of commercial products, and its incorporation into a mouthrinse could be an alternative for improving the antimicrobial efficacy of the oral product.

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Antimicrobial activity of four different dental gel formulas on cariogenic bacteria evaluated using the linear regression method

Cited by 15 publications

References 15 publications

Formulation, physicochemical evaluation and antimicrobial activity of green toothpaste on streptococcus mutans

Formulation, physicochemical evaluation and antimicrobial activity of green toothpaste on streptococcus mutans

Antimicrobial Efficacy of Commercially Available Toothpastes – An In vitro Study

Antimicrobial efficacy of Curcuma zedoaria extract as assessed by linear regression compared with commercial mouthrinses

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