Background: The use of antimicrobial chemotherapeutic agent has been proposed as a means of reducing the levels of oral bacteria. Many chemotherapeutic agents claim to have antimicrobial properties. Hence this in vitro study had been undertaken. Methods: This in vitro study comprised of seven toothpastes which have been tested for their antimicrobial activity against three oral pathogens namely, Streptococcus mutans, Escherichia coli and Candida albicans by well agar diffusion assay at the dilution of 1:1, 1:2, 1:4, 1:8 and 1:16. Results: Study results showed that toothpaste 'five' with sodium fluoride and sylodent as main ingredients showed maximum zone of inhibition against Streptococcus mutans where as against Candida albicans, toothpaste 'six' with xylitol and sodium fluoride as main ingredients showed maximum zone of inhibition. And against E. coli, toothpaste 'one' with Triclosan and Zinc sulphate as main ingredients showed maximum zone of inhibition among all toothpastes. It was observed that tooth paste 'six' with sodium fluoride and Neem, Meswak as main ingredient showed minimum zone of inhibition against Streptococcus mutans at 1:1 dilution among seven toothpastes used in the present study. Conclusion: In the present study, it has been demonstrated that triclosan containing toothpastes formulations are more effective in control of oral micro flora.
Background and Objective:Preterm birth (PTB) is an important issue in public health and is a major cause for infant mortality and morbidity. There is a growing consensus that systemic diseases elsewhere in the body may influence PTB. Recent studies have hypothesized that maternal periodontitis could be a high-risk factor for PTB. The aim of the present study was to investigate the relationship between maternal periodontitis on PTB.Materials and Methods:Forty systemically healthy primiparous mothers aged 18–35 years were recruited for the study. Based on inclusion and exclusion criteria, they were categorized into PTB group as cases and full term birth group (FTB) as controls. PTB cases (n = 20) defined as spontaneous delivery before/<37 completed weeks of gestation. Controls (FTB) were normal births at or after 37 weeks of gestation. Data on periodontal status, pregnancy outcome variables, and information on other factors that may influence adverse pregnancy outcomes were collected within 2 days of labor. Data were subjected to Student's t-test and Pearson's correlation coefficient statistical analysis.Results:Statistically significant difference with respect to the gestational period at the time of delivery and birth weight of the infants in (PTB) group (<0.001) compared to (FTB) group was observed. Overall, there was statistically significant poor periodontal status in the (PTB) group compared to (FTB) group. The statistical results also showed a positive correlation between gestational age and clinical parameters.Conclusion:An observable relationship was noticed between periodontitis and gestational age, and a positive correlation was found with respect to PTB and periodontitis. Further studies should be designed to establish periodontal disease as an independent risk factor for PTB/preterm low birth weight.
Key-Messages:Botulinum toxin or popularly known as Botox worldwide, is a neurotoxin which when used in therapeutic doses can produce wonders in cosmetic problems of orofacial regions. Its applications are not just restricted to cosmetic therapy but also has got wide array of uses in the treatment of painful dentalconditions. This article reviews the various applications of Botox in dentistry and its current status in India.
Background: A recent innovation in dentistry is the use of second generation platelet concentrate which is an autologous platelet rich fibrin gel (PRF) with growth factors and cicatricial properties for root coverage procedures. The aim of this study was to determine the addition of an autologous plateletrich fibrin membrane (PRF) to coronally advanced flap (CAF) (site A) would improve the clinical outcome compared to an CAF alone (Site B) for the treatment of isolated Miller's Class I or II gingival recessions. Materials and Methods: Ten subjects, presenting isolated bilateral Miller Class I or II gingival recessions of similar extent were enrolled in the study. The mean recession depth value at baseline was 3.30 ± 0.95 mm for test sites and 3.30 ± 0.95 mm for control sites. Each patient was treated on both sides by CAF technique; the combination treatment (with PRF membrane) was applied on the test side. Probing depth (PD), recession width, clinical attachment level (CAL), keratinized gingival width, and gingival/mucosal thickness (GTH) were measured at baseline, 1 month, 3 months and at 6 months post-surgery. Results: At 6 months, complete root coverage was obtained at 73.86% of the sites treated with the test (site A) procedure but 67.52% of root coverage at the site B. A statistically significant difference between the two sites (A & B) in relation to gingival thickness was observed at 3 and 6 months. At 6 months, the increase in GTH was statistically significant when comparing the test sites (from 1.13 ± 0.08 mm at baseline to 1.58 ± 0.12 mm at 6 months) to the control sites (from 1.13 ± 0.08 mm at baseline to 1.31 ± 0.07 mm at 6 months). In the case of Recession width, PD, CAL and Width of keratinized gingiva (WKG) there was no significant difference. Conclusion: The addition of PRF membrane with CAF provides superior root coverage with additional benefits of gain in CAL and WKG at 6 months postoperatively.
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