Antibiotic Resistance — A Cause for Reemergence of Infections

Subramaniam, Girish; Girish, Meenakshi

doi:10.1007/s12098-019-03180-3

Cited by 61 publications

(43 citation statements)

References 31 publications

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“…Due to the overuse of antibiotics, many bacteria have developed resistance to antibiotics, which greatly reduces the antibacterial effect (Kuehn, 2018;Durand et al, 2019;Subramaniam and Girish, 2020). For the sake of finding new antibacterial agents that are not easy to produce drug resistance and have excellent antibacterial effect to replace antibiotics, people have focused on inorganic antibacterial agents, including various metal/metal oxide nanoparticles, carbon nanomaterials and nanosilicate materials.…”

Section: Combination With Inorganic Antimicrobialsmentioning

confidence: 99%

Latest Advances on Bacterial Cellulose-Based Antibacterial Materials as Wound Dressings

Luo

et al. 2020

Front. Bioeng. Biotechnol.

128

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At present, there are various wound dressings that can protect the wound from further injury or isolate the external environment in wound treatment. Whereas, infection and slow self-healing still exist in wound healing process. Therefore, it is urgent to develop an ideal wound dressing with good biocompatibility and strong antibacterial activity to promote wound healing. Bacterial cellulose is a kind of promising biopolymer because it can control wound exudate and provide a moist environment for wound healing. However, the lack of antibacterial activity limits its application. In this paper, the advantages of bacterial cellulose as wound dressings were introduced, and the preparation and research progress of bacterial cellulose-based antibacterial composites in recent years were reviewed, including adding antibiotics, combining with inorganic antibacterial agents or organic antibacterial agents. Finally, the existing problems and future development direction of bacterial cellulose-based antibacterial wound dressings were discussed.

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Section: Combination With Inorganic Antimicrobialsmentioning

confidence: 99%

Latest Advances on Bacterial Cellulose-Based Antibacterial Materials as Wound Dressings

Luo

et al. 2020

Front. Bioeng. Biotechnol.

128

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“…Rezistența la preparatele antimicrobiene reprezintă o enormă criză globală în sănătatea publică și una dintre cele mai grave amenințări cu care se confruntă oamenii astăzi. Medicina modernă a determinat evoluția suplimentară a rezistenței antimicrobiene prin consumul excesiv de antibiotice [1][2][3].…”

Section: ключевые слова: противомикробные препараты грамотрицательные бактерии резистентностьunclassified

Antimicrobial resistance. Characteristic of resistance to antimicrobial preparations of Gram-negative bacteria

Bucov¹,

Burduniuc²,

Bălan³

et al. 2021

SPEMM

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The scope is the literature review on the resistance of Gramnegative bacteria to antimicrobial preparations is presented. 131 different materials were analyzed, including WHO documents and scientifi c publications. Bacterial resistance remains a significant threat and a leading cause of death worldwide. Resistant bacteria proliferate by natural selection when drug-sensitive ones are removed by antibiotics. These organisms can be spread to all health care facilities as well in community, which requires increased attention to infection control measures and the administration of β-lactamcontaining medicines in an effort to control the selection of other even more harmful pathogens. Several strategies for combating and controlling Gram-negative resistant bacteria have been reported, such as the development of antimicrobial auxiliaries, structural modifi cation of existing antibiotics, research and study of chemical structures with new mechanisms of action. In addition to new therapy, an effective infection control system, along with the prudent use of antimicrobials, is extremely important.

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“…Antibiotics supplement the body's natural defense mechanism against microbial infections and are having high demand ever since their discovery, which provides ample evidence of their critical role in world economy and public health. In human medicine, antimicrobial agents have played a significant role in the treating common ailments as well as in surgeries, organ transplantation, stem cell therapy, and chemotherapy (Subramaniam & Girish, 2020). The immense use of antibiotics in modern medicine has paved the way for the development of antibiotic resistance in a wide range of Gram‐positive and Gram‐negative bacteria that can be categorized into three categories namely urgent serious and concerning threats (Subramaniam & Girish, 2020).…”

Section: Introductionmentioning

confidence: 99%

“…In human medicine, antimicrobial agents have played a significant role in the treating common ailments as well as in surgeries, organ transplantation, stem cell therapy, and chemotherapy (Subramaniam & Girish, 2020). The immense use of antibiotics in modern medicine has paved the way for the development of antibiotic resistance in a wide range of Gram-positive and Gram-negative bacteria that can be categorized into three categories namely urgent serious and concerning threats (Subramaniam & Girish, 2020). Antimicrobial agents have also been extensively used in agriculture-agrifood industry from where they enter human environments and move about with people and goods, creating effective transborder resistance ( Figure 1) (Likotrafiti et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Cysteine‐rich antimicrobial peptides from plants: The future of antimicrobial therapy

Srivastava

Dashora

Ameta

et al. 2020

Phytotherapy Research

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There has been a spurt in the spread of microbial resistance to antibiotics due to indiscriminate use of antimicrobial agents in human medicine, agriculture, and animal husbandry. It has been realized that conventional antibiotic therapy would be less effective in the coming decades and more emphasis should be given for the development of novel antiinfective therapies. Cysteine rich peptides (CRPs) are broad‐spectrum antimicrobial agents that modulate the innate immune system of different life forms such as bacteria, protozoans, fungi, plants, insects, and animals. These are also expressed in several plant tissues in response to invasion by pathogens, and play a crucial role in the regulation of plant growth and development. The present work explores the importance of CRPs as potent antimicrobial agents, which can supplement and/or replace the conventional antibiotics. Different plant parts of diverse plant species showed the presence of antimicrobial peptides (AMPs), which had significant structural and functional diversity. The plant‐derived AMPs exhibited potent activity toward a range of plant and animal pathogens, protozoans, insects, and even against cancer cells. The cysteine‐rich AMPs have opened new avenues for the use of plants as biofactories for the production of antimicrobials and can be considered as promising antimicrobial drugs in biotherapeutics.

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Antibiotic Resistance — A Cause for Reemergence of Infections

Cited by 61 publications

References 31 publications

Latest Advances on Bacterial Cellulose-Based Antibacterial Materials as Wound Dressings

Latest Advances on Bacterial Cellulose-Based Antibacterial Materials as Wound Dressings

Antimicrobial resistance. Characteristic of resistance to antimicrobial preparations of Gram-negative bacteria

Cysteine‐rich antimicrobial peptides from plants: The future of antimicrobial therapy

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