Antibacterial and photocatalytic activities of 5-nitroindole capped bimetal nanoparticles against multidrug resistant bacteria

Manoharan, Ranjith Kumar; Muthusubramanian, Shanmugam; Gangadaran, Prakash; Ahn, Young‐Ho

doi:10.1016/j.colsurfb.2020.110825

Cited by 27 publications

(13 citation statements)

References 51 publications

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“…Although there is one report claiming indole increases persistence with E. coli (Vega et al, 2012), consistent and overwhelming evidence has shown indole and substituted indoles reduce persistence in both Bacteria and Archaea (Hu et al, 2015;Kwan et al, 2015;Lee et al, 2016;Megaw and Gilmore, 2017;Li et al, 2019;Song et al, 2019;Manoharan et al, 2020;Masuda et al, 2020;Sun et al, 2020;Yam et al, 2020). For years, this was perplexing but it seems the most-probable reason for this different result lies in the solvent utilized to solubilize indole.…”

Section: Conflicting Persistence Results With Indole Due To Diluentsmentioning

confidence: 99%

“…For example, 5-methylindole (Figure 3) combined with tobramycin kills methicillin-resistant S. aureus and Staphylococcus epidermidis persisters (Sun et al, 2020). In addition, 5-nitroindole (Figure 3) kills E. coli, P. aeruginosa, and Enterobacter tabaci persister cells, and its effectiveness was increased by combining it with copper and zinc nanoparticles (Manoharan et al, 2020).…”

Section: Indole-related Compounds (Indigoids) Kill Persister Cellsmentioning

confidence: 99%

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Combatting Persister Cells With Substituted Indoles

Song

Wood

2020

Front. Microbiol.

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Given that a subpopulation of most bacterial cells becomes dormant due to stress, and that the resting cells of pathogens can revive and reconstitute infections, it is imperative to find methods to treat dormant cells to eradicate infections. The dormant bacteria that are not spores or cysts are known as persister cells. Remarkably, in contrast to the original report that incorrectly indicated indole increases persistence, a large number of indole-related compounds have been found in the last few years that kill persister cells. Hence, in this review, along with a summary of recent results related to persister cell formation and resuscitation, we focus on the ability of indole and substituted indoles to combat the persister cells of both pathogens and non-pathogens.

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Section: Conflicting Persistence Results With Indole Due To Diluentsmentioning

confidence: 99%

Section: Indole-related Compounds (Indigoids) Kill Persister Cellsmentioning

confidence: 99%

Combatting Persister Cells With Substituted Indoles

Song

Wood

2020

Front. Microbiol.

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“…We used XPS to study the structure and surface element composition of different catalysts. The C 1s spectra of CN, pCN-N and pCN-N/ZIS-Z in Figure 5a show three main characteristic peaks at 284.8 eV, 286.2 eV and 288.3 eV, which can be attributed to adventitious carbon species(C-C), sp 3 -bonded carbon C-NH x (x = 1, 2) on the edges of heptazine units and sp 2 -bonded carbon in (N-C=N), respectively [50]. It can be found that pCN-N has a new characteristic peak at 288.7 eV compared to CN, which corresponds to C=O [47], which can be attributed to oxygen-doping.…”

Section: Photocatalyst Characterizationmentioning

confidence: 99%

“…Therefore, exploring low-cost, simple and environmentally friendly methods to produce hydrogen has become an important research topic [1,2]. At the same time, with the progress of human society and the development of the industrial age, the use of antibiotics has increased due to the emergence of a variety of new diseases, and the entry of antibiotics into water will pose risks to human health and ecosystems [3][4][5][6][7]. Among them, metronidazole (MNZ) (Figure S1a) is one of the most widely used antibiotics.…”

Section: Introductionmentioning

confidence: 99%

Flower-Like Dual-Defective Z-Scheme Heterojunction g-C3N4/ZnIn2S4 High-Efficiency Photocatalytic Hydrogen Evolution and Degradation of Mixed Pollutants

Hou

Jin

et al. 2021

Nanomaterials

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Graphitic carbon nitride (g-C3N4) with a porous nano-structure, nitrogen vacancies, and oxygen-doping was prepared by the calcination method. Then, it was combined with ZnIn2S4 nanosheets containing zinc vacancies to construct a three-dimensional (3D) flower-like Z-scheme heterojunction (pCN-N/ZIS-Z), which was used for photocatalytic hydrogen evolution and the degradation of mixed pollutants. The constructed Z-scheme heterojunction improved the efficiency of photogenerated charges separation and migration, and the large surface area and porous characteristics provided more active sites. Doping and defect engineering can change the bandgap structure to improve the utilization of visible light, and can also capture photogenerated electrons to inhibit recombination, so as to promote the use of photogenerated electron-hole pairs in the photocatalytic redox process. Heterojunction and defect engineering synergized to form a continuous and efficient conductive operation framework, which achieves the hydrogen production of pCN-N/ZIS-Z (9189.8 µmol·h−1·g−1) at 58.9 times that of g-C3N4 (155.9 µmol·h−1·g−1), and the degradation rates of methyl orange and metronidazole in the mixed solution were 98.7% and 92.5%, respectively. Our research provides potential ideas for constructing a green and environmentally friendly Z-scheme heterojunction catalyst based on defect engineering to address the energy crisis and environmental restoration.

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“…Metal-based antibacterial materials were among the first investigated and showed high antibacterial properties, often able to kill resistant bacteria [23][24][25][26][27][28][29][30]. However, rising concerns about their cytotoxicity against mammalian cells oriented the research to more biocompatible materials such as carbon-based materials.…”

Section: Introductionmentioning

confidence: 99%

Properties, mechanism and applications of diamond as an antibacterial material

et al. 2021

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antibiotic resistance in bacteria is a current threat causing an increasing number of infections of difficult clinical management. While the overuse and misuse of antibiotics are investigated to reduce them, the need for alternatives to approaches is rising. carbon-based materials shown recent moderate to high antibacterial properties and diamond, thanks to its superior mechanical, tribological, electrical, chemical and biological quality is a choice material to investigate for safe antibacterial films, coatings and particles. here, the antibacterial properties of diamond films, nanodiamonds, Dlc films and a comprehensive list of the composites developed from them are discussed along with a summary of the bacterial strains used and the most efficient composition and/or concentration discovered. in a later stage, the mechanisms of action and the parameters that are believed to influence them are discussed and finally, an overview of the biomedical and food industry applications is given.

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Antibacterial and photocatalytic activities of 5-nitroindole capped bimetal nanoparticles against multidrug resistant bacteria

Cited by 27 publications

References 51 publications

Combatting Persister Cells With Substituted Indoles

Combatting Persister Cells With Substituted Indoles

Flower-Like Dual-Defective Z-Scheme Heterojunction g-C3N4/ZnIn2S4 High-Efficiency Photocatalytic Hydrogen Evolution and Degradation of Mixed Pollutants

Properties, mechanism and applications of diamond as an antibacterial material

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