Antibacterial activity of East African medicinal plants

Fabry, Werner; Okemo, P. O.; Ansorg, R.

doi:10.1016/s0378-8741(97)00128-1

Cited by 305 publications

(184 citation statements)

References 12 publications

Supporting

Mentioning

152

Contrasting

Unclassified

Order By: Relevance

“…The ethanolic extract from the stem of L. pacari showed MIC values of 625 μg/mL for all strains of S. aureus. These values (Table 2) (Fabry et al, 1998), whilst values ranging 64 -1000 μg/mL against bacteria, and 32 -128 μg/mL against dermatophytes, were reported for Alstonia macrophylla (Chattopadhyay et al, 2001 (Koné et al, 2004), and extracts of Quercus infectoria and Punica granatum were highly effective against Escherichia coli (O157:H7) with MIC values of 90 and 190 μg/mL, respectively (Voravuthikunchai et al, 2004).…”

Section: Resultsmentioning

confidence: 81%

The antibiotic activity of some Brazilian medicinal plants

Lima¹,

Ximenes²,

Luna³

et al. 2006

Rev. bras. farmacogn.

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 81%

The antibiotic activity of some Brazilian medicinal plants

Lima¹,

Ximenes²,

Luna³

et al. 2006

Rev. bras. farmacogn.

View full text Add to dashboard Cite

show abstract

“…However if considered a more flexible stringent criteria indicating that extracts having activities with MIC values below 8 mg/ml [27] are considered to possess some antimicrobial activity and natural products with MIC values below 1 mg/ml are considered noteworthy [28,29], the overall activity recorded therefore with the extracts, compounds 4 , and 5 could be considered as important, highlighting the antimicrobial potency of A. communis . However, the tested samples were less active than chloramphenicol and nystatin used as reference antibiotic on most of the microbial strains.…”

Section: Resultsmentioning

confidence: 99%

Antimicrobial activities of the methanol extract and compounds from Artocarpus communis (Moraceae)

Kuete

Ango

Fotso

et al. 2011

BMC Complement Altern Med

View full text Add to dashboard Cite

BackgroundArtocarpus communis is used traditionally in Cameroon to treat several ailments, including infectious and associated diseases. This work was therefore designed to investigate the antimicrobial activities of the methanol extract (ACB) and compounds isolated from the bark of this plant, namely peruvianursenyl acetate C (1), α-amyrenol or viminalol (2), artonin E (4) and 2-[(3,5-dihydroxy)-(Z)-4-(3-methylbut-1-enyl)phenyl]benzofuran-6-ol (5).MethodsThe liquid microdilution assay was used in the determination of the minimal inhibitory concentration (MIC) and the minimal microbicidal concentration (MMC), against seven bacterial and one fungal species.ResultsThe MIC results indicated that ACB as well as compounds 4 and 5 were able to prevent the growth of all tested microbial species. All other compounds showed selective activities. The lowest MIC value of 64 μg/ml for the crude extract was recorded on Staphylococcus aureus ATCC 25922 and Escherichia coli ATCC 8739. The corresponding value of 32 μg/ml was recorded with compounds 4 and 5 on Pseudomonas aeruginosa PA01 and compound 5 on E. coli ATCC 8739, their inhibition effect on P. aeruginosa PA01 being more than that of chloramphenicol used as reference antibiotic.ConclusionThe overall results of this study provided supportive data for the use of A. communis as well as some of its constituents for the treatment of infections associated with the studied microorganisms.

show abstract

“…Obtidos os valores de CIM e CBM, os extratos vegetais de E. anomala e P. salutare foram avaliados quanto a sua ação antimicrobiana de acordo com os valores de CIM contra os patógenos estudados onde extratos que apresentam CIM<100 µg/mL têm potencial antimicrobiano promissor (bom), CIM entre 100 -500 µg/mL possui atividade inibitória moderada, CIM entre 500 -1.000 µg/mL apresenta atividade inibitória fraca e extratos que apresentaram CIM superior a 1.000 µg/mL são inativos frente aos patógenos (Fabry et al, 1998;Holetz et al, 2002;Dall'Agnol et al, 2003;Tanaka et al, 2005;Chavasco et al, 2014).…”

Section: Atividade Antimicrobianaunclassified

Avaliação da atividade antimicrobiana de extratos de Eugenia anomala e Psidium salutare (Myrtaceae) frente à Escherichia coli e Listeria monocytogenes

Simonetti

Ethur

Castro

et al. 2016

Rev. bras. plantas med.

View full text Add to dashboard Cite

RESUMO:As doenças transmitidas por alimentos ocorrem principalmente devido à ingestão de alimentos contaminados por microrganismos patogênicos, dentre eles a Escherichia coli e Listeria monocytogenes. Uma das alternativas estudadas para minimizar a contaminação de alimentos é o emprego de plantas, ou seus extratos, como agentes antimicrobianos de origem natural em produtos alimentícios. Desta forma o objetivo do presente estudo é fornecer dados científicos a respeito de duas plantas nativas do RS ainda não estudadas, Eugenia anomala e Psidium salutare, visando potencial emprego como agente antimicrobiano natural em alimentos. Para tanto, avaliou-se a atividade antimicrobiana de extratos de E. anomala e P. salutare contra E. coli e L. monocytogenes através da determinação da concentração inibitória mínima (CIM) pelo método de microdiluição em caldo, a capacidade antioxidante dos extratos por meio do método de redução do radical DPPH e a citotoxicidade in vitro empregando células CHO-K1. Os resultados obtidos mostraram que os extratos de acetato de etila e etanólico de ambas as espécies possuem ação antioxidante muito alta, de 94,08% e 93,86%, respectivamente. Apenas o extrato hexânico de P. salutare apresentou ação antimicrobiana moderada (CIM = 312,5 µg/mL). Todos os extratos apresentaram ação citotóxica sendo que os maiores percentuais foram do extrato clorofórmico de E. anomala (77,05%) e hexânico de P. salutare (76,79%), na concentração de 100 µg/mL. Assim, o presente estudo demonstrou que as espécies vegetais estudadas apresentam potencial para emprego como agente antimicrobiano destes microrganismos.Palavras-chave: Concentração Inibitória Mínima, Citotoxicidade in vitro, Atividade Antioxidante.ABSTRACT: Evaluation of the antimicrobial activity of extracts of Eugenia anomala and Psidium salutare (Myrtaceae) against the Escherichia coli and Listeria monocytogenes. The foodborne diseases occur mainly due to the ingestion of food contaminated by pathogenic microorganisms, including Escherichia coli and Listeria monocytogenes. One of the alternatives studied to minimize contamination of food is the use of plants or their extracts as antimicrobial agents naturally occurring in food products. The objective of this study is to provide scientific data on two native plants of RS have not studied Eugenia anomala and Psidium salutare for a potential use as a natural antimicrobial agent in food. To this end, we evaluated the antimicrobial activity of extracts of E. anomala and P. salutare against E. coli and L. monocytogenes by determining the minimum inhibitory concentration (MIC) by the broth microdilution method, the antioxidant capacity of the extract for means DPPH radical reduction method and in vitro cytotoxicity using CHO-K1 cells. The results showed that the ethyl acetate and ethanolic extracts of both species have very high antioxidant activity, of 94.08% and 93.86%, respectively. Only the hexane extract of P. salutare showed a moderate antimicrobial activity (MIC = 312.5 mg/mL). Moreover, all extracts showed ...

show abstract

Antibacterial activity of East African medicinal plants

Cited by 305 publications

References 12 publications

The antibiotic activity of some Brazilian medicinal plants

The antibiotic activity of some Brazilian medicinal plants

Antimicrobial activities of the methanol extract and compounds from Artocarpus communis (Moraceae)

Avaliação da atividade antimicrobiana de extratos de Eugenia anomala e Psidium salutare (Myrtaceae) frente à Escherichia coli e Listeria monocytogenes

Contact Info

Product

Resources

About