Anti-inflammatory, antioxidant and anti- Mycobacterium tuberculosis activity of viridiflorol: The major constituent of Allophylus edulis (A. St.-Hil., A. Juss. &amp; Cambess.) Radlk.

Trevizan, Lucas Noboru Fatori; Nascimento, Kamilla Felipe do; Santos, Joyce Alencar; Kassuya, Cândida Aparecida Leite; Cardoso, Cláudia Andréa Lima; Vieira, Maria do Carmo; Moreira, Flora Martinez Figueira; Croda, Júlio; Formagio, Anelise Samara Nazari

doi:10.1016/j.jep.2016.08.053

Cited by 75 publications

(39 citation statements)

References 26 publications

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“…The authors found no response regarding fresh mass of leaf and stem and concluded that species native to Cerrado are undemanding for fertilization. The positive response to organic fertilization in this study results from the different conditions of soil, climate, and others, it is, therefore, important to produce more leaf mass and consequently more secondary metabolites (Knapik et al, 2005;Torales et al, 2014;Trevizan et al, 2016).…”

Section: Discussionmentioning

confidence: 87%

“…Vacum oil has viridiflorol (30.88%) as main constituent. It is used against Mycobacterium tuberculosis, and as a natural antiinflammatory, antimycobacterial and antioxidant (Trevizan et al, 2016).…”

Section: Discussionmentioning

confidence: 99%

“…ex Niederl (vacum, Sapindaceae) is native to Brazil, occurring in the Cerrado of Mato Grosso do Sul and Minas Gerais. Its leaves have medicinal properties against throat inflammations (Trevizan et al, 2016), diarrhea (Umeo et al, 2011), and antimicrobial and antioxidant activities due to the presence of phenolic compounds such as alkaloids, flavonoids, and essential oils (steroid and Rev. Ceres, Viçosa, v. 66, n.5, p. 351-362, sep/oct, 2019 triterpenoid) in its chemical composition (Tirloni et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

“…Ceres, Viçosa, v. 66, n.5, p. 351-362, sep/oct, 2019 triterpenoid) in its chemical composition (Tirloni et al, 2015). Economically, it is used as wood in carpentry and afforestation of cities; the ripe fruits are sweet and eaten by birds and other animals (Umeo et al, 2011;Trevizan et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

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Intercropping with Tropaeolum majus and fertilization with chicken manure on yield of Allophylus edulis

et al. 2019

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Section: Discussionmentioning

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Intercropping with Tropaeolum majus and fertilization with chicken manure on yield of Allophylus edulis

et al. 2019

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“…The MIC of its essential oils is 157.5 µg/ml, and varidiflorol's, which is the main component of the plant, is 190.0 µg/ml. This result may indicate synergism between the components of A. edulis' extract, or that another component displays the most antimycobacterial active, and not the varidiflorol [17]. Plumbagin, a substance isolated from the root of Plumbago indica also has promising properties and is active against reference, MDR and XDR M. tuberculosis.…”

Section: Extracts and Natural Substances Isolated From Plantsmentioning

confidence: 99%

Anti-tubercular substances produced by plants

Polak¹,

Kapka‐Skrzypczak²

2017

J Pre Clin Clin Res.

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Tuberculosis is one of the common causes of death worldwide, and according to the World Health Organization, in 2015, about 10.4 mln people globally is suffering from that disease. Despite great development in medicine and discovery of many antimycobacterial drugs, tuberculosis remains an unsolved problem. The populations of countries in Africa, Asia and South America have difficult access to hygiene, medical care and medicines, and they therefore resort to consulting traditional practitioners who mainly use drugs from natural sources which they prepare themselves. Plants are the biggest source of such medicines and are used as extracts, decoctions or powders, often without any evidence of their actual activity. Isolates from plants sometimes contain unknown substances or some second metabolites of microorganisms. In vitro studies have shown that some of these medicines have effective antimycobacterial properties, even against clinical, resistant strains. This is hopeful in the situation where more and more cases of tuberculosis prove to be resistant to standard drugs. Extracts of medicinal plants are often synergistic with synthetic drugs. Substances with insufficient MIC can be a basis for derivatives which have better properties. This thesis summarizes the current international knowledge of the use of plant substances used in the treatment of tuberculosis that could be potential new antituberculous drugs.

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Mineral Content, Antioxidant Activity and Essential Oil of Allophylus edulis (A. St.‐Hil., A. Juss. & Cambess.) Radlk. Leaves: Plant from South American Biodiversity

Piekarski-Barchik

Ávila

Ferreira

et al. 2021

Chemistry & Biodiversity

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Allophylus edulis (A. St.‐Hil., A. Juss. & Cambess.) Radlk. (Sapindaceae) is an edible plant from the South American biodiversity that is a potential source of bioactive compounds. The mineral content and antioxidant activity of Allophylus edulis leaves were investigated, as well as the composition and the antioxidant activity of the essential oil. The mineral content was determined by ICP – OES and the antioxidant assays were assessed by ABTS, DPPH and FRAP. The essential oil was obtained by hydrodistillation and analyzed by GC/MS. Calcium, potassium, phosphorus, sulfur, and magnesium were the main minerals found in A. edulis leaves. Of the toxic metals that were present, a low level of aluminum was detected. The essential oil of A. edulis has (E)‐nerolidol as major compound and both, the leaves, and the essential oil isolated from the leaves have antioxidant potential. These findings could provide a framework for developing new food and non‐food products with A. edulis leaves.

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Anti-inflammatory, antioxidant and anti- Mycobacterium tuberculosis activity of viridiflorol: The major constituent of Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk.

Cited by 75 publications

References 26 publications

Intercropping with Tropaeolum majus and fertilization with chicken manure on yield of Allophylus edulis

Intercropping with Tropaeolum majus and fertilization with chicken manure on yield of Allophylus edulis

Anti-tubercular substances produced by plants

Mineral Content, Antioxidant Activity and Essential Oil of Allophylus edulis (A. St.‐Hil., A. Juss. & Cambess.) Radlk. Leaves: Plant from South American Biodiversity

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