Anthocyanins from Ipomoea batatas L. effect on ovarian malondialdehyde and 17β-estradiol in rats exposed cigarette smoke

Aningsih, Baharika Suci Dwi; Sujuti, Hidayat; Mustofa, Edy; Ratnawati, Retty

doi:10.15275/rusomj.2020.0308

Cited by 7 publications

(3 citation statements)

References 24 publications

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“…This study shows that purple sweet potato anthocyanin can be a powerful antioxidant to prevent oxidative stress induced by cigarette smoke. Anthocyanins can act as antioxidants by reducing free radicals and scavenging free radicals by donating electrons to free radicals [9,17,18] Anthocyanin is a type of polyphenol among flavonoids that can directly or indirectly reduce oxidative damage by preventing the increase of free radicals in the body. Anthocyanin is a flavonoid and a polyphenol that acts as an antioxidant.…”

Section: Resultsmentioning

confidence: 99%

Efficacy of Ipomoea batatas L. anthocyanin in reducing mammary Malondialdehyde levels in female rats exposed to tobacco smoke

Rahman¹,

Ningrum²,

Aningsih³

et al. 2023

GSC Biol. Pharm. Sci.

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Objectives: Tobacco smoke is one source of free radicals that can enter the body through the respiratory tract and circulate through the bloodstream to reach all organs in the body. Purple sweet potato (Ipomoea batatas L.) anthocyanin is a potentially powerful antioxidant that reduces free radicals. This study aims to demonstrate that purple sweet potato anthocyanin can reduce mammary gland malondialdehyde concentrations in female white rats (Rattus norvegicus) exposed to tobacco smoke. Methods: This was experimental research with a randomized post-test control group. Thirty female white rats were used in this study. These samples were then divided into two control groups (negative control group - no exposure to tobacco smoke and anthocyanin; positive control group - exposure to tobacco smoke only -) and three exposure groups of exposure to cigarette smoke at a rate of two sticks/day and variety Anthocyanin doses for eight weeks. The malondialdehyde content of the mammary gland was measured spectrophotometrically. Results: The result showed that the higher dose of Ipomoea batatas L anthocyanin administered, the lower the MDA level in the breasts of rats exposed to cigarette smoke (ANOVA test, p-value = 0.002) Conclusions: Ipomoea batatas L. anthocyanin can decrease the concentration of mammary gland malondialdehyde in female rats exposed to tobacco smoke.

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Section: Resultsmentioning

confidence: 99%

Efficacy of Ipomoea batatas L. anthocyanin in reducing mammary Malondialdehyde levels in female rats exposed to tobacco smoke

Rahman¹,

Ningrum²,

Aningsih³

et al. 2023

GSC Biol. Pharm. Sci.

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“…6 Likewise, research conducted by Zhao et al (2013) states that the work of anthocyanins as antioxidants can increase enzymatic antioxidants in the body, such as GSH-PX and SOD. In addition, anthocyanins can reduce MDA levels, which is an indicator of oxidative stress [14,15].…”

Section: Resultsmentioning

confidence: 99%

The effect of anthocyanin of purple sweet potato (Ipomoea Batatas L) on cervical malondialdehyde levels of female rats (Rattus Norvegicus) exposed to cigarette smoke

Purwaningsih¹,

Aningsih²,

Utami³

et al. 2022

GSC Biol. and Pharm. Sci.

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Cigarette smoke contains oxidants that generate the production of free radicals. Free radical is a form of Reactive Oxygen Species (ROS). However, an increase in ROS production will cause an imbalance between ROS and antioxidants, leading to oxidative stress. Oxidative stress will induce lipid peroxidation, measurable by malondialdehyde (MDA) concentration. Anthocyanin is an exogenic antioxidant able to inhibit ROS. This study aimed to prove the effect of anthocyanin obtained from purple sweet potato to decrease MDA concentration in the cervix uterine of female rats (Rattus norvegicus) exposed to cigarette smoke. This study was an experimental study with a Randomized Post Test Only Control Group Design on 30 white female rats weighing 150-200 grams and aged 1.5-2 months, divided into 2 control groups and 3 treatment groups. One group was exposed to cigarette smoke (2 cigarettes/day) for 8 weeks without anthocyanine as the positive control group, and one group was not exposed to either cigarette smoke or anthocyanin as the negative control group. The 3 treatment groups received cigarette smoke exposure (2 cigarettes/day) and were given anthocyanin with a dosage of 20, 40, and 80 mg/kg/day, respectively, for 8 weeks. The concentration of cervical MDA was measured by the spectrophotometric method. The result showed a significant difference in MDA concentration between the positive control and the negative control groups with a P<0.05. There was no significant difference between the 20 and 40 mg/kg treated groups compared to the positive control group. The 80 mg/kg anthocyanin-treated group showed a significant difference in MDA cervix uterine concentration compared to the positive control group with a P<0.05.

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“…Kebutuhan manusia terhadap vitamin dan mineral juga bisa didapatkan dengan mengonsumsi ubi jalar. Ubi jalar merupakan sumber antosianin dan bermanfaat untuk antikarsinogenik, antimutagenik dan antioksidan (Jiao et al, 2012;El Husna et al, 2013;Hambali et al, 2014;Sukardi et al, 2018;Aningsih et al, 2020). Ubi jalar bisa diolah menjadi beberapa bahan makanan salah satunya sebagai tepung (Nindyarani dan Suparmo, 2011;Prasetya, 2011;Dewandari et al, 2014;Monica et al, 2018).…”

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PENGARUH PUPUK KANDANG DAN PUPUK ORGANIK LIMBAH BATANG PISANG TERHADAP PERTUMBUHAN UBI JALAR (Ipomoea batatas L.)

Wati¹,

Shalihy

2022

ZMIP

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Banana stem is still not optimally utilized by the communities that it causes as waste. One alternative solution is to process banana stem to be compost and liquid organic fertilizer, which is environmentally friendly to optimize plant growth and production. In this study, the compost and liquid organic fertilizer of banana stem applied on sweet potatoes. This study examines the compost and organic fertilizer of banana stem response on sweet potato (Ipomoea batatas L.). This research was conducted from October to December 2019 in the greenhouse of the Manokwari Agricultural Development Polytechnic. The research design used a one-factor Completely Randomized Block Design. The variables observed in the study were tendril length, root length, number of shoots, number of leaves, and fresh weight. The research data were analyzed using variance and Duncan's Multiple Distance Test (DMRT) at the 5% significance level. The results showed that the treatment of soil media + manure + liquid organic fertilizer of banana stems (1: 1: 1) gave the best result for the growth of tendril length (126.75 cm), root length (64.25 cm), number of leaves (56 fruits), the number of shoots (11 shoots), while the treatment of soil media + manure + banana stem compost with a ratio (1: 1: 1) impacted positively to wet weight (26.5 gr) of sweet potato.

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Anthocyanins from Ipomoea batatas L. effect on ovarian malondialdehyde and 17β-estradiol in rats exposed cigarette smoke

Cited by 7 publications

References 24 publications

Efficacy of Ipomoea batatas L. anthocyanin in reducing mammary Malondialdehyde levels in female rats exposed to tobacco smoke

Efficacy of Ipomoea batatas L. anthocyanin in reducing mammary Malondialdehyde levels in female rats exposed to tobacco smoke

The effect of anthocyanin of purple sweet potato (Ipomoea Batatas L) on cervical malondialdehyde levels of female rats (Rattus Norvegicus) exposed to cigarette smoke

PENGARUH PUPUK KANDANG DAN PUPUK ORGANIK LIMBAH BATANG PISANG TERHADAP PERTUMBUHAN UBI JALAR (Ipomoea batatas L.)

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