ANALYSIS OF SECONDARY METABOLITES, ANTIBACTERIAL ACTIVITY AND COMPOUND COMPOSITION IN THE SEA CUCUMBER Bohadschia sp.  EXTRACT

Rasyid, Abdullah

doi:10.29244/jitkt.v8i2.15831

Cited by 3 publications

(1 citation statement)

References 4 publications

(4 reference statements)

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“…Until now, Indonesia has not been able to process sea cucumbers into products that provide more benefits. For example, in medicine, golden sea cucumbers also have high antioxidant activity to ward off free radicals 9 . Support for the trust of local people in the archipelago such as in Malaysia who believe that commercial dry sea cucumbers and smoked sea cucumbers have properties that can cure various diseases such as cancer, asthma, hypertension, rheumatism, skin damage, and degenerative diseases 10 .…”

Section: Introductionmentioning

confidence: 99%

Repairing of Renal Tubules in Diabetic Rats (Rattus norvegicus) Diabetes After Administration of Golden Sea Cucumber (Stichopus hermanii)

Setianingsih¹,

Wisnumarta²,

Tjandra³

2021

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This study aims to analyze the improvement of the histopathological picture of renal tubules in diabetic rats after being given golden sea cucumber extract (Stichopus hermanii). This research uses experimental design laboratories with a post-test only control group design method. The sampling used simple random sampling with 25 white rats divided into five groups, namely groups that were given standard feed without STZ-induced, STZ-induced group, STZ-induced group and given golden sea cucumber extract at a dose of 4.25 mg/kg BW for 21 days, STZinduced group and given golden sea cucumber extract at a dose of 8.5 mg/kg BW for 21 days, and STZ-induced group and given gold sea cucumber extract at a dose of 12.75 mg/kg BW for 21 days. The data on the observation of each group's kidney histopathology was carried out at the end of the session. The results of the analysis using the Kruskal-Wallis Test showed significant results, the Mann-Whitney Test showed significant differences between the STZinduced group and the golden sea cucumber extract (Stichopus hermanii) dose of 12.75 mg/kg BW (x=7.4 mg/dl) decreased significantly (p=0.001) compared to the STZ-only-induced group (x=12.6 mg/dl). Administration of golden sea cucumber extract (Stichopus hermanii) at a dose of 12.75 mg/kg BW of rats for 21 days lowered the degree of tubular damage to the kidney rectus of white rats (Rattus norvegicus) male streptozotocin-induced strains.

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Section: Introductionmentioning

confidence: 99%

Repairing of Renal Tubules in Diabetic Rats (Rattus norvegicus) Diabetes After Administration of Golden Sea Cucumber (Stichopus hermanii)

Setianingsih¹,

Wisnumarta²,

Tjandra³

2021

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Antiviral activity of the sea cucumber tegument extract (Pattalus mollis) on human rotavirus A (RVA)

García-Candela

Pariona-Velarde²,

Mondragón-Martínez

et al. 2019

Natural Product Research

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Isolation of sea cucumbers’s (Holothuria atra) secondary metabolite using column-chromatography technique

Agustina

Bella

Karina

et al. 2021

IOP Conf. Ser.: Earth Environ. Sci.

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Identification of sea cucumbers from Benteng Inong Balee, Aceh Besar and their phytochemistry screening were conducted in December 2020 to January 2021 at Laboratory of Marine Chemistry and Fisheries Biotechnology, Universitas Syiah Kuala. The purpose of this study was to identify the species of sea cucumbers and its secondary metabolite content using phytochemistry screening and column chromatography. The species of sea cucumbers that were identified was Holothuria atra. The extraction method used in sea cucumber extraction was maceration method, while the separation of secondary metabolites used column-chromatography with eluent of n-hexane : ethyl acetate (8:4). The results showed that secondary metabolites obtained from phytochemical tests were flavonoids, saponins and triterpenoids.

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ANALYSIS OF SECONDARY METABOLITES, ANTIBACTERIAL ACTIVITY AND COMPOUND COMPOSITION IN THE SEA CUCUMBER Bohadschia sp. EXTRACT

Cited by 3 publications

References 4 publications

Repairing of Renal Tubules in Diabetic Rats (Rattus norvegicus) Diabetes After Administration of Golden Sea Cucumber (Stichopus hermanii)

Repairing of Renal Tubules in Diabetic Rats (Rattus norvegicus) Diabetes After Administration of Golden Sea Cucumber (Stichopus hermanii)

Antiviral activity of the sea cucumber tegument extract (Pattalus mollis) on human rotavirus A (RVA)

Isolation of sea cucumbers’s (Holothuria atra) secondary metabolite using column-chromatography technique

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