An implantable ZigBee ready telemetric platform for in vivo monitoring of physiological parameters

Valdastri, Pietro; Rossi, Stefano Marco Maria De; Menciassi, Arianna; Lionetti, Vincenzo; Bernini, Fabio; Recchia, Fabio A.; Dario, P.

doi:10.1016/j.sna.2007.04.035

Cited by 48 publications

(15 citation statements)

References 18 publications

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“…But the quality of those frequency bands have been improving rapidly and their sensitivity levels have come into the target range for realizing communication between intra and extracorporeal transmitters and receivers. Valdastri [24] and Iris De Falco [8] indicated the possibility of 0.9 GHz communication in vivo. Our previous study provided the direct evidence that the 2.4 GHz frequency band could be used in vivo.…”

Section: Discussionmentioning

confidence: 99%

Innovations Leading Capsule Endoscopy into the New Frontier: Screening and Therapy at Home

Ohta

2015

IEICE Trans. Commun.

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SUMMARYThis paper proposed patient friendly capsule endoscopy (CE) for not only screening but also treatment. Two different types of CEs with an Internet utility were investigated. The first type used magnetic navigation in the stomach and colon for screening. Magnetic navigation enabled the capsule to explore the whole of the gastrointestinal tract with less risk of missing lesions and complete the screening within the battery life. The system's design was patiently friendly as it allowed the subjects to leave the hospital after the capsule had been navigated in the stomach. The second investigated two different therapeutic robotic endoscopes. Both prototypes were driven by DC motors and controlled remotely via the internet. In addition, they were equipped with therapeutic tools and each prototype's ability with the tools was assessed. The investigation showed it was possible to remotely control both prototypes and operate therapeutic tools via the Internet. The investigation identified areas for improvement, such as size, connection speed, security of data, and the holding the capsule's position during treatment, In conclusion, both methods have the potential to make capsule endoscopy a very patient friendly procedure that can be carried out anywhere.

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Section: Discussionmentioning

confidence: 99%

Innovations Leading Capsule Endoscopy into the New Frontier: Screening and Therapy at Home

Ohta

2015

IEICE Trans. Commun.

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“…Despite tissue absorption at 2.4 GHz, previous work [25], [26] has demonstrated that this can still be a viable solution for implantable devices. A full ZigBee stack [27] can be implemented, when required, without any further hardware modification.…”

Section: Hardware Descriptionmentioning

confidence: 99%

Wireless Implantable Electronic Platform for Chronic Fluorescent-Based Biosensors

Valdastri

Susilo

Forster

et al. 2011

IEEE Trans. Biomed. Eng.

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Abstract-The development of a long-term wireless implantable biosensor based on fluorescence intensity measurement poses a number of technical challenges, ranging from biocompatibility to sensor stability over time. One of these challenges is the design of a power efficient and miniaturized electronics, enabling the biosensor to move from bench testing to long term validation, up to its final application in human beings. In this spirit, we present a wireless programmable electronic platform for implantable chronic monitoring of fluorescent-based autonomous biosensors. This system is able to achieve extremely low power operation with bidirectional telemetry, based on the IEEE802.15.4-2003 protocol, thus enabling over three-year battery lifetime and wireless networking of multiple sensors. During the performance of single fluorescent-based sensor measurements, the circuit drives a laser diode, for sensor excitation, and acquires the amplified signals from four different photodetectors. In vitro functionality was preliminarily tested for both glucose and calcium monitoring, simply by changing the analyte-binding protein of the biosensor. Electronics performance was assessed in terms of timing, power consumption, tissue exposure to electromagnetic fields, and in vivo wireless connectivity. The final goal of the presented platform is to be integrated in a complete system for blood glucose level monitoring that may be implanted for at least one year under the skin of diabetic patients. Results reported in this paper may be applied to a wide variety of biosensors based on fluorescence intensity measurement.Index Terms-Biotelemetry, calcium sensing, chronic implants, fluorescence-based biosensor, fluorescence resonant energy transfer (FRET), glucose monitoring, implantable devices.

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“…Diagnosis of constipation and its subtypes is based on symptoms and various physiologic tests including ano-rectal manometry, defecography, rectal barostat test, measures of colonic transit, and colonic manometry [4][5][6][7][8][9][10][11][12]. Ano-rectal and colonic manometry can cause skin irritation or infections, thus contributing to deteriorating health conditions [13]. Defecography has drawbacks of radiation exposure, embarrassment, interobserver bias, and inconsistent methodology [14].…”

Section: Introductionmentioning

confidence: 99%

A study of human colonic motility in healthy and constipated subjects using the wireless capsule

Lü

Yan

Sun

2015

Computers in Biology and Medicine

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An implantable ZigBee ready telemetric platform for in vivo monitoring of physiological parameters

Cited by 48 publications

References 18 publications

Innovations Leading Capsule Endoscopy into the New Frontier: Screening and Therapy at Home

Innovations Leading Capsule Endoscopy into the New Frontier: Screening and Therapy at Home

Wireless Implantable Electronic Platform for Chronic Fluorescent-Based Biosensors

A study of human colonic motility in healthy and constipated subjects using the wireless capsule

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