Innovations Leading Capsule Endoscopy into the New Frontier: Screening and Therapy at Home

Ohta, Hidetoshi

doi:10.1587/transcom.e98.b.526

Cited by 5 publications

(2 citation statements)

References 24 publications

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“…53 Other recent developments in WCE technology include tele-operated, global access, and cloud-based architectures for screening and therapeutics. 54,55,56…”

Section: A2 Physiological Sensing and Therapeuticsmentioning

confidence: 99%

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Magnetically guided capsule endoscopy

et al. 2017

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Wireless capsule endoscopy (WCE) is a powerful tool for medical screening and diagnosis, where a small capsule is swallowed and moved by means of natural peristalsis and gravity through the human gastrointestinal (GI) tract. The camera-integrated capsule allows for visualization of the small intestine, a region which was previously inaccessible to classical flexible endoscopy. As a diagnostic tool, it allows to localize the sources of bleedings in the middle part of the gastrointestinal tract and to identify diseases, such as inflammatory bowel disease (Crohn's disease), polyposis syndrome, and tumors. The screening and diagnostic efficacy of the WCE, especially in the stomach region, is hampered by a variety of technical challenges like the lack of active capsular position and orientation control. Therapeutic functionality is absent in most commercial capsules, due to constraints in capsular volume and energy storage. The possibility of using body-exogenous magnetic fields to guide, orient, power, and operate the capsule and its mechanisms has led to increasing research in Magnetically Guided Capsule Endoscopy (MGCE). This work shortly reviews the history and state-of-art in WCE technology. It highlights the magnetic technologies for advancing diagnostic and therapeutic functionalities of WCE. Not restricting itself to the GI tract, the review further investigates the technological developments in magnetically guided microrobots that can navigate through the various air-and fluid-filled lumina and cavities in the body for minimally invasive medicine.

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“…53 Other recent developments in WCE technology include tele-operated, global access, and cloud-based architectures for screening and therapeutics. 54,55,56…”

Section: A2 Physiological Sensing and Therapeuticsmentioning

confidence: 99%

“…The IntelliCap ® capsule developed by Medimetrics B.V. (the Netherlands) allows for custom liquid‐based drug loading and tunable release profile . Other recent developments in WCE technology include tele‐operated, global access, and cloud‐based architectures for screening and therapeutics …”

Section: State Of the Art In Research And Developmentmentioning

confidence: 99%

Magnetically guided capsule endoscopy

et al. 2017

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A more acceptable endoluminal implantation for remotely monitoring ingestible sensors anchored to the stomach wall

Ohta¹,

Izumi

Yoshimoto

2015

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

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Several types of implant devices have been proposed and introduced into healthcare and telemedicine systems for monitoring physiological parameters, sometimes for very long periods of time. To our disappointment, most of the devices are implanted invasively and by surgery. We often have to surgically remove such devices after they have finished their mission or before the battery becomes worn out. Wearable devices have the possibility to become new modalities for monitoring vital parameters less-invasively. However, for round-the-clock monitoring of data from sensors over long periods of time, it would be better to put them inside the body to avoid causing inconvenience to patients in their daily lives. This study tested a less invasive endoluminal approach and innovative tools (developed during our research into therapeutic capsule endoscopy) for remotely anchoring ingestible sensors to the stomach wall. Preliminary investigations are also described about wireless communication (NFC, ZigBee, and Bluetooth) for low power consumption and inductive extracorporeal power feeding wirelessly to the circuits in a phantom lined with swine gastric mucosa. Electrocardiogram and pH were monitored and those parameters were successfully transmitted by wireless communication ICs to the Internet via a portable device.

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Using magnetic resonance wireless power transfer to operate a scalpel on a prototype of a robotic therapeutic endoscope

Ohta

2016

2016 10th International Symposium on Medical Information and Communication Technology (ISMICT)

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Innovations Leading Capsule Endoscopy into the New Frontier: Screening and Therapy at Home

Cited by 5 publications

References 24 publications

Magnetically guided capsule endoscopy

Magnetically guided capsule endoscopy

A more acceptable endoluminal implantation for remotely monitoring ingestible sensors anchored to the stomach wall

Using magnetic resonance wireless power transfer to operate a scalpel on a prototype of a robotic therapeutic endoscope

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