Amino acid side chain-like surface modification on magnetic nanoparticles for highly efficient separation of mixed proteins

Fe3O4@ZnS@Glycine nanoparticle as a novel microwave stimulus controlled drug release system

“…Glycine is an organic molecule containing carboxyl and amino, was modified on the surface of Fe 3 O 4 @ZnS nanoparticles and has good biocompatibility. This can also be verified from some research reports [21,22]. Compared with unmodified Fe 3 O 4 @ZnS nanoparticles, the introduction of glycine made the nanoparticles more biocompatible, which is more advantageous to the interaction between the Fe 3 O 4 @ZnS nanoparticles and organic drug molecules containing hydroxyl, amino and carboxyl.…”

“…3a) shows a strong peak at 580 cm -1 , which corresponds to the vibration of Fe-O [21]. In the 3435 cm -1 frequency region, the increased broad peak associates with the stretching vibration bands of -OH groups [18].…”

“…Glycine is the structure simplest organic small molecule in amino acid series. Glycine was widely used in modification of inorganic nanoparticles because its functional groups (-COOH and -NH 2 ) in the molecules can form complexes with different types of organic or inorganic molecules for a variety of drug load, low cytotoxicity and biocompatibility [21,22]. Therefore, the core-shell structured nanoparticles have glycine-modified layer as supporters to load the anticancer drug, and a further combination of Fe 3 O 4 and ZnS nanoparticles in a single nanoparticle endows these kinds of materials with drug target delivery and microwave-controlled release.…”

Fabrication and BSA Adsorption/Desorption Properties of Titania/Silica Composite Films Modified with Silane Coupling Agents

“…The abovementioned results indicated that the present composite films can change the BSA adsorption/desorption behavior under light irradiation. Furthermore, surface modification with silane coupling agents having various terminal functional groups has been used for the separation of amino acids 5,6 . The present methodology is expected to lead to novel separation materials with the promise to enable the separation of amino acids through photoinduced superhydrophilicity and through interactions between the amino acids and terminal functional groups.…”

Fabrication and Functionalization of Inorganic Materials Using Amphiphilic Molecules

“…Photoinduced superhydrophilicity resulted in the desorption of BSA from the composite film. Surface modification with silane coupling agents having various terminal functional groups has been used for the separation of amino acids 71,72 . This methodology can aid the preparation of novel separation materials for biomolecules using photoinduced superhydrophilicity and the interactions between the biomolecules and terminal functional groups of the silane coupling agents.…”