Aktivitas Antimikroba Ekstrak Rimpang Jeringau (Acorus calamus) Terhadap Pertumbuhan Candida albicans

Susanti, Nurlaili

doi:10.15575/biodjati.v1i1.1037

Cited by 10 publications

(7 citation statements)

References 2 publications

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“…Flavonoids are phenolic compounds that can denature proteins in enzymes thereby disrupting cell metabolic activities. Flavanoids also have the ability to form bonds with cell wall proteins, so that bacteria are unable to attach and invade cells (Susanti, 2016). Flavonoids are also able to release transduction energy in the bacterial cell membrane thereby inhibiting bacterial motility (Manik et al, 2016).…”

Section: Results and Analysismentioning

confidence: 99%

Antibacterial Activity Test Of Kawista Fruit Peel Extract (Limonia Acidissima L.) From Pasinan Village, Pasuruan, Against Salmonella Sp Colonies In Vitro

Prastyaningtias,

Sari Dian

2023

Int J Ecophysiol

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One of the potential agricultural products from Pasinan Village, Lekok sub-district, Pasuruan, East Java Province is Kawista Fruit. Residents of Pasinan used kawista fruit for consumption, both raw and ripe. The large consumption of this kawista fruit leaves an abundance of fruit peels. Based on the results of phytochemical analysis, the extract of kawista fruit peel contains saponins, tannins, alkaloids, flavonoids, and terpenoids. Another income source of Pasinan residents comes from marine resources, that can be served in fresh fish, dried fish and other processed fish is susceptible to contaminated by microorganisms such as Salmonella sp. Salmonella sp. is pathogenic microbe lives on intestines of animals and humans. This study aims to determine the antibacterial activity of kawista rind extract on the growth of Salmonella sp. in-vitro and to determine the concentration of Kawista rind extract which is effective for inhibiting the growth of Salmonella sp using the paper disc diffusion method. The results of this study, the diameter of the inhibitory zone for the growth of Salmonella sp. using variables concentrations of kawista rind extract at 12.5%;25%;50%;75%;100%, with negative control of aquadest and methanol and positive control is tetracycline. At a concentration of 100% Kawista extract, the diameter of the bacterial inhibition test was the largest and significantly different from another treatment group at concentrations of 12.5%;25%;50%;75%. However, the 100% Kawista extract showed a smaller inhibitory zone than the tetracycline treatment group, but not significantly different. In methanol treatment, the inhibition test showed that the diameter of the bacteria was greater than Kawista extract treatment group of 12.5%;25%;50%;75% but not significantly different. Based on the results of the study, it can be concluded that kawista rind extract is effective for inhibiting the growth of Salmonella sp. bacteria, Kawista rind extract at a concentration of 100% is most effective for inhibiting the growth of Salmonella sp bacteria and shows results that are not significantly different from tetracycline

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Section: Results and Analysismentioning

confidence: 99%

Antibacterial Activity Test Of Kawista Fruit Peel Extract (Limonia Acidissima L.) From Pasinan Village, Pasuruan, Against Salmonella Sp Colonies In Vitro

Prastyaningtias,

Sari Dian

2023

Int J Ecophysiol

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“…Zat aktif dari saponin merusak permeabilitas membran pada bakteri (Sudarmi et al, 2017). Senyawa flavonoid memberikan penghambatan pada bakteri dengan membentuk kompleks dengan protein ekstraseluler mikroba, sedangkan senyawa tanin mengkoagulasi protoplasma mikroba dengan cara membentuk ikatan dengan (Susanti et al, 2016). Senyawa triterpenoid sebagai antibakteri, yaitu dengan merusak porin yang terdapat pada membran luar dinding sel bakteri (Rini et al, 2017) KESIMPULAN Ekstrak etanol 96 % buah pare dapat menghambat pertumbuhan bakteri Staphylococcus aureus pada kosentrasi 100 % sebesar 6,32 mm.…”

Section: Hasil Uji Daya Sebarunclassified

Inhibitory Capacity of Clay Mask 96% Ethanol Extract from Bitter Melon (Momordica charantia L.) Against Staphylococcus aureus

2022

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Momordica charantia L. commonly known as bitter melon plant, is widely used as a treatment for various diseases, including skin infections. The purpose of this study was to determine the highest concentration of bitter melon extract and infusion in inhibiting the growth of Staphylococcus aureus bacteria. This research was conducted using the disc diffusion method and evaluation of the quality of the clay mask was carried out on the growth of Staphylococcus aureus bacteria. The results showed that 96 % ethanol extract of bitter melon at a concentration of 100% had an inhibitory effectiveness of 6.32 mm and was higher than that of 4.85 mm of bitter melon infusion. The clay mask formula of 96% ethanol extract of bitter melon with concentrations of 5 % (F1), 7.5 % (F2) and 10 % (F3) gave a fairly good evaluation of physical quality with an inhibition zone of 5.0 mm; 7.06 mm and 7.30 mm, respectively. The clay mask of 96% ethanol extract of bitter melon fruit F1, F2 and F3 belongs to the medium category in inhibiting bacteria.keywords: inhibition; ethanol extract; clay mask; Momordica charantia L.; Staphylococcus aureusABSTRAKDaya Hambat Masker Clay Ekstrak Etanol 96% Buah Pare (Momordica charantia L.) terhadap Bakteri Staphylococcus aureusMomordica charantia L. umumnya dikenal dengan tanaman pare, digunakan sebagai pengobatan terhadap berbagai penyakit, diantaranya infeksi pada kulit. Penelitian ini bertujuan untuk mengetahui konsentrasi tertinggi ekstrak dan infusa buah pare dalam menghambat pertumbuhan bakteri Staphylococcus aureus. Penelitian ini dilakukan menggunakan metode difusi cakram dan evaluasi mutu masker clay dilakukan terhadap pertumbuhan bakteri Staphylococcus aureus. Hasil penelitian menunjukkan bahwa ekstrak etanol 96 % buah pare pada konsentrasi 100 % memiliki efektivitas daya hambat sebesar 6,32 mm dan lebih tinggi dibandingkan dengan infusa buah pare 4,85 mm. Formula masker clay ekstrak etanol 96 % buah pare konsentrasi 5 % (F1) ; 7,5 % ; (F2) dan 10 % (F3) memberikan hasil evaluasi mutu fisik yang cukup baik dengan zona hambat berturut-turut 5,0 mm ; 7,06 mm dan 7,30 mm. Masker clay ekstrak etanol 96% buah pare F1, F2 dan F3 termasuk ke dalam kategori sedang dalam menghambat bakteri.Kata kunci: daya hambat; ekstrak etanol; masker clay; Momordica charantia L.; Staphylococcus aureus

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“…Senyawa fenol seperti flavonoid yang bekerja dengan cara mendenaturasi protein yang dapat menyebabkan aktivitas metabolisme sel dikatalis oleh suatu enzim yang merupakan protein. Karena flavonoid memiliki kemampuan untuk membentuk kompleks dengan protein ekstraseluler terlarut dan dengan dinding sel, sehingga mikroorganisme tidak dapat melekat dan menginvasi sel (Susanti, 2016). Saponin bertindak sebagai penghalang kimia dalam sistem pertahanan tanaman menghadapi patogen.…”

Section: Uji Potensi Antibakteriunclassified

POTENSI EKSTRAK ETANOL KULIT BUAH MATOA (Pometia pinnata J.R Forst & G.Forst) TERHADAP BAKTERI PENYEBAB KARIES GIGI

2021

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One of the infectious diseases that occur in the oral cavity is dental caries (cavities). The bacteria that play a role in the occurrence of infection are Streptococcus mutans bacteria, and the matoa plant is one of the plants that can act as antibacterial (Pometia pinnata J.R Forst) which has high efficacious compounds. This study aimed to determine the activity and potency of the ethanolic extract of matoa fruit peel (Pometia pinnata J.R Forst & G. Forst) against Streptococcus mutans bacteria. This research is a laboratory experimental research. Matoa fruit peel simplicia was extracted by maceration method with 96% ethanol solvent, then tested for phytochemical screening to determine the class of compounds contained in the matoa fruit peel. Furthermore, the activity was tested against Streptococcus mutans bacteria using a positive control of chloramphenicol antibiotics and a negative control of Dimethyl Sulfoxide. After that, the values of the Minimum Inhibitory Level and Minimum Killer were measured. From these results, it was continued to test the antibacterial potential using the Kirby Bauer method. The results showed that the ethanol extract of matoa fruit peel (Pometia pinnata J.R Forst & G. Forst) had activity against Streptococcus mutans bacteria. The potential value of the matoa fruit peel extract against Streptococcus mutans bacteria at concentrations of 25%, 50% and 75%, respectively, was 11.75 mm, 15.82 mm and 18.75 mm which was included in the category of strong inhibition.

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Aktivitas Antimikroba Ekstrak Rimpang Jeringau (Acorus calamus) Terhadap Pertumbuhan Candida albicans

Cited by 10 publications

References 2 publications

Antibacterial Activity Test Of Kawista Fruit Peel Extract (Limonia Acidissima L.) From Pasinan Village, Pasuruan, Against Salmonella Sp Colonies In Vitro

Antibacterial Activity Test Of Kawista Fruit Peel Extract (Limonia Acidissima L.) From Pasinan Village, Pasuruan, Against Salmonella Sp Colonies In Vitro

Inhibitory Capacity of Clay Mask 96% Ethanol Extract from Bitter Melon (Momordica charantia L.) Against Staphylococcus aureus

POTENSI EKSTRAK ETANOL KULIT BUAH MATOA (Pometia pinnata J.R Forst & G.Forst) TERHADAP BAKTERI PENYEBAB KARIES GIGI

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