AGE-Related Differences of Novel Atherosclerotic Risk Factors and Angiographic Profile Among Gujarati Acute Coronary Syndrome Patients

Abstract

Context: Although numerous risk factors have been established to predict the development of acute coronary syndrome (ACS), the risk factor profile may be different between the younger and older individuals. Aim:To analyse the frequency and pattern of atherogenic risk factors and angiographic profiles in age-stratified Gujarati patients with ACS. Materials and Methods:ACS patients undergoing coronary angiography at U.N.

Demographic and angiographic profile in premature cases of acute coronary syndrome: analysis of 820 young patients from South India

“…If the current trend continues, the burden of CAD in India will surpass other regions of the world by the year 2020 (5). In addition to higher rate, it is also reported that Indian individuals may develop CAD at a very early age (6). According to an estimate, more than half of death related to cardiovascular disease occurs in patients below the age of 50 years and one-fourth of acute myocardial infarction cases are being reported in patients under the age of 40 years (6).…”

“…According to an estimate, more than half of death related to cardiovascular disease occurs in patients below the age of 50 years and one-fourth of acute myocardial infarction cases are being reported in patients under the age of 40 years (6). It has also been noted that the clinical presentation, risk factor profile, and coronary anatomy of young patients who develop CAD differs to those who develops CAD at an older age (1,6,7). Overall, these studies have indicated that patients with early onset of CAD exhibit preponderance of singlevessel disease, and dominance of coronary risk factors such as hypercholesterolemia, family history of CAD, and cigarette smoking as compared to older patients.…”

“…In addition to higher rate, it is also reported that Indian individuals may develop CAD at a very early age (6). According to an estimate, more than half of death related to cardiovascular disease occurs in patients below the age of 50 years and one-fourth of acute myocardial infarction cases are being reported in patients under the age of 40 years (6). It has also been noted that the clinical presentation, risk factor profile, and coronary anatomy of young patients who develop CAD differs to those who develops CAD at an older age (1,6,7).…”

“…Therefore, we aimed to identify the differences between risk factor profile and coronary angiographic characteristics of young adults presenting with ST-elevated myocardial infarction (STEMI), non-ST-elevated myocardial infarction (NSTEMI), or unstable angina (UA). We selected an age cut-off of 40 years to define a premature CAD, based on previous Indian studies (6,8).…”

Coronary Angiography in Patients With Premature Acute Coronary Syndrome and Family Hypercholesterolemia

“…Это согласуется с данными исследований, в которых многососудистое поражение было характерно для больных старших возрастных групп [14]. Также оказалось, что средний уровень ЛПНП в группе 2,3-сосудистого/поражения ствола ЛКА составил 3,5±1,4ммоль/л, а при однососуди-стом/незначимом поражении 2,9±1,0ммоль/л (p<0,001) (табл.…”