Advancements in Fabrication and Application of Chitosan Composites in Implants and Dentistry: A Review

Sharifianjazi, Fariborz; Khaksar, Samad; Esmaeilkhanian, Amirhossein; Bazli, Leila; Eskandarinezhad, Sara; Salahshour, Peyman; Sadeghi, Farnaz; Rostamnia, Sadegh; Vahdat, Seyed Mohammad

doi:10.3390/biom12020155

Cited by 44 publications

(27 citation statements)

References 133 publications

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“…Several examples of chitosan-based matrices for bone applications have been reported. However, due to its mechanical weakness [ 94 ], there is a need to combine chitosan with other materials in applications for bone tissue engineering [ 95 ]. Nanoparticles formed using chitosan display interesting properties, such as low toxicity; good absorbability, permeability, and moisture retention; and is easily degradable.…”

Section: Biopolymers For Medical Applicationsmentioning

confidence: 99%

Biopolymer: A Sustainable Material for Food and Medical Applications

et al. 2022

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Biopolymers are a leading class of functional material suitable for high-value applications and are of great interest to researchers and professionals across various disciplines. Interdisciplinary research is important to understand the basic and applied aspects of biopolymers to address several complex problems associated with good health and well-being. To reduce the environmental impact and dependence on fossil fuels, a lot of effort has gone into replacing synthetic polymers with biodegradable materials, especially those derived from natural resources. In this regard, many types of natural or biopolymers have been developed to meet the needs of ever-expanding applications. These biopolymers are currently used in food applications and are expanding their use in the pharmaceutical and medical industries due to their unique properties. This review focuses on the various uses of biopolymers in the food and medical industry and provides a future outlook for the biopolymer industry.

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Section: Biopolymers For Medical Applicationsmentioning

confidence: 99%

Biopolymer: A Sustainable Material for Food and Medical Applications

et al. 2022

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“…Freeze-drying is an industrial procedure that is employed to assure the long-term durability and preservation of pharmaceutical and biomedical products [ 41 ]. Freeze-drying works by freezing the material, lowering the surrounding pressure, and applying sufficient heat to enable the substance’s frozen water to sublimate straight from the solid matrix to the gaseous state.…”

Section: Methods Of Fabrication Of Chitosan Productsmentioning

confidence: 99%

Drug-Loaded Chitosan Scaffolds for Periodontal Tissue Regeneration

et al. 2022

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Chitosan is a natural anionic polysaccharide with a changeable architecture and an abundance of functional groups; in addition, it can be converted into various shapes and sizes, making it appropriate for a variety of applications. This article examined and summarized current developments in chitosan-based materials, with a focus on the modification of chitosan, and presented an abundance of information about the fabrication and use of chitosan-derived products in periodontal regeneration. Numerous preparation and modification techniques for enhancing chitosan performance, as well as the uses of chitosan and its metabolites, were reviewed critically and discussed in depth in this study. Chitosan-based products may be formed into different shapes and sizes, considering fibers, nanostructures, gels, membranes, and hydrogels. Various drug-loaded chitosan devices were discussed regarding periodontal regeneration.

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“…In addition, CS itself has the property of accelerating the rate of wound healing and promoting bone formation. CS has been used in wound dressings, implant scaffolds, and dental applications [ 128 ]. Cellulose acetate (CA) nanofiber with CS and propolis promotes burned skin repair [ 129 ].…”

Section: Electrospinning In the Treatment Of Oral Ulcersmentioning

confidence: 99%

Advances in the Application of Electrospun Drug-Loaded Nanofibers in the Treatment of Oral Ulcers

et al. 2022

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Oral ulcers affect oral and systemic health and have high prevalence in the population. There are significant individual differences in the etiology and extent of the disease among patients. In the treatment of oral ulcers, nanofiber films can control the drug-release rate and enable long-term local administration. Compared to other drug-delivery methods, nanofiber films avoid the disadvantages of frequent administration and certain side effects. Electrospinning is a simple and effective method for preparing nanofiber films. Currently, electrospinning technology has made significant breakthroughs in energy-saving and large-scale production. This paper summarizes the polymers that enable oral mucosal adhesion and the active pharmaceutical ingredients used for oral ulcers. Moreover, the therapeutic effects of currently available electrospun nanofiber films on oral ulcers in animal experiments and clinical trials are investigated. In addition, solvent casting and cross-linking methods can be used in conjunction with electrospinning techniques. Based on the literature, more administration systems with different polymers and loading components can be inspired. These administration systems are expected to have synergistic effects and achieve better therapeutic effects. This not only provides new possibilities for drug-loaded nanofibers but also brings new hope for the treatment of oral ulcers.

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Advancements in Fabrication and Application of Chitosan Composites in Implants and Dentistry: A Review

Cited by 44 publications

References 133 publications

Biopolymer: A Sustainable Material for Food and Medical Applications

Biopolymer: A Sustainable Material for Food and Medical Applications

Drug-Loaded Chitosan Scaffolds for Periodontal Tissue Regeneration

Advances in the Application of Electrospun Drug-Loaded Nanofibers in the Treatment of Oral Ulcers

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